Patents by Inventor Matthias Stuber

Matthias Stuber has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20210041519
    Abstract: A method and a system automatically perform an image reconstruction of a biological object. The method includes acquiring at different time points t_i signal data for imaging the biological object and clustering a set of data in connection with the acquired signal data. The clustering includes constructing a matrix C, wherein an element Ci,j of the matrix C is the value n_j of one of the data of the dataset acquired at the time point t_i, and then performing a similarity clustering based on the matrix C. At least one of the clusters is selected and determining for each of the time points t_i that are part of the cluster all acquired signal data that have been acquired within a predefined temporal threshold with respect to the considered time point t_i. The image reconstruction of the biological object is performed with the previously determined acquired signal data.
    Type: Application
    Filed: August 10, 2020
    Publication date: February 11, 2021
    Inventors: DAVIDE PICCINI, JOHN HEERFORDT, CHRISTOPHER ROY, MATTHIAS STUBER
  • Publication number: 20180289262
    Abstract: The disclosure relates to a method for the interactive acquisition of data from an object under investigation by a magnetic resonance system. The data is acquired from the object under investigation with the magnetic resonance system and images are automatically reconstructed and displayed in real time based on the data. A time interval is determined during which a predetermined condition is met in the images. Quality images are automatically reconstructed based on the data acquired within the time interval. The temporal resolution during reconstruction of the quality images is higher than the temporal resolution during reconstruction of the images.
    Type: Application
    Filed: April 3, 2018
    Publication date: October 11, 2018
    Inventors: Jérôme Chaptinel, Tobias Kober, Davide Piccini, Peter Speier, Matthias Stuber, Jérôme Yerly
  • Patent number: 9007061
    Abstract: Featured are methods for magnetic resonance imaging of a volume, such a volume having susceptibility-generating objects or interfaces having susceptibility mismatches therein. Such a method includes selectively visualizing one of susceptibility-generating objects or interfaces having susceptibility mismatches as hyperintense signals, where such visualizing includes controlling variable imaging parameters so as to control a geometric extent of a signal enhancing effect, m more particular aspects of the present invention, such selectively visualizing includes attenuating or essentially suppressing signals from fat and/or water, namely on-resonant water protons, so as to thereby enhance a signal(s) associated with magnetic susceptibility gradient(s). Also featured are MRI systems, apparatuses and/or applications programs for execution on a computer system controlling the MRI data acquisition process embodying such methods.
    Type: Grant
    Filed: October 24, 2011
    Date of Patent: April 14, 2015
    Assignee: The Johns Hopkins University
    Inventors: Matthias Stuber, Wesley D. Gilson, Dara L. Kraitchman
  • Publication number: 20120062227
    Abstract: Featured are methods for magnetic resonance imaging of a volume, such a volume having susceptibility-generating objects or interfaces having susceptibility mismatches therein. Such a method includes selectively visualizing one of susceptibility-generating objects or interfaces having susceptibility mismatches as hyperintense signals, where such visualizing includes controlling variable imaging parameters so as to control a geometric extent of a signal enhancing effect, m more particular aspects of the present invention, such selectively visualizing includes attenuating or essentially suppressing signals from fat and/or water, namely on-resonant water protons, so as to thereby enhance a signal(s) associated with magnetic susceptibility gradient(s). Also featured are MRI systems, apparatuses and/or applications programs for execution on a computer system controlling the MRI data acquisition process embodying such methods.
    Type: Application
    Filed: October 24, 2011
    Publication date: March 15, 2012
    Applicant: The Johns Hopkins University
    Inventors: Matthias Stuber, Wesley D. Gilson, Dara L. Kraitchman
  • Patent number: 8054075
    Abstract: Featured are methods for magnetic resonance imaging of a volume, such a volume having susceptibility-generating objects or interfaces having susceptibility mismatches therein. Such a method includes selectively visualizing one of susceptibility-generating objects or interfaces having susceptibility mismatches as hyperintense signals, where such visualizing includes controlling variable imaging parameters so as to control a geometric extent of a signal enhancing effect, m more particular aspects of the present invention, such selectively visualizing includes attenuating or essentially suppressing signals from fat and/or water, namely on-resonant water protons, so as to thereby enhance a signal(s) associated with magnetic susceptibility gradient(s). Also featured are MRI systems, apparatuses and/or applications programs for execution on a computer system controlling the MRI data acquisition process embodying such methods.
    Type: Grant
    Filed: February 3, 2006
    Date of Patent: November 8, 2011
    Assignee: The Johns Hopkins University
    Inventors: Matthias Stuber, Wesley D. Gilson, Dara L. Kraitchman
  • Patent number: 7800366
    Abstract: Three-dimensional MR motion estimation on a single image plane based on tagged MRI and HARP processing. Tagged magnetic resonance imaging technique encodes and automatically tracks displacement of spatially modulated object in three dimensions, encoding both in plane and through-plane motion in a single image plane without affecting acquisition speed. Post-processing unravels encoding in order to directly track 3-D displacement of points within the image plane throughout image sequence. The invention is particularly suited to use on a heart for tracking and determining myocardial displacement. In one embodiment, an MR pulse sequence extends a slice following complementary spatial modulation of magnetization (CSPAMM) pulse sequence with two small z-encoding gradients immediately before the readouts in successive CSPAMM acquisitions, thereby adding a through-plane encoding from which through-plane motion can be computed from acquired images.
    Type: Grant
    Filed: January 13, 2009
    Date of Patent: September 21, 2010
    Assignee: Johns Hopkins University
    Inventors: Jerry L. Prince, Matthias Stuber, Nael Fakhry Osman, Khaled Zakarya Abd-Elmoniem
  • Patent number: 7787930
    Abstract: Adiabatic pulses that define an amplitude modulation and a frequency modulation are applied in a sequence of pulses to obtain a T2 weighted magnetic resonance image. Such an adiabatic T2 prep sequence typically includes a first 90° pulse, an even number of adiabatic pulses, and a second 90° pulse. Adiabatic pulses can be selected based on function pairs, or can be defined numerically. A magnetic resonance imaging (MRI) system includes a library of adiabatic pulse waveforms, and is configured to select a waveform and apply an RF magnetic field based on the selected pulse waveform.
    Type: Grant
    Filed: June 6, 2005
    Date of Patent: August 31, 2010
    Assignees: The United States of America as represented by the Department of Health and Human Services, The Johns Hopkins University
    Inventors: Reza Nezafat, Ronald Ouwerkerk, Matthias Stuber
  • Patent number: 7495438
    Abstract: Three-dimensional MR motion estimation on a single image plane based on tagged MRI and HARP processing. Tagged magnetic resonance imaging technique encodes and automatically tracks displacement of spatially modulated object in three dimensions, encoding both in plane and through-plane motion in a single image plane without affecting acquisition speed. Post-processing unravels encoding in order to directly track 3-D displacement of points within the image plane throughout image sequence. The invention is particularly suited to use on a heart for tracking and determining myocardial displacement. In one embodiment, an MR pulse sequence extends a slice following complementary spatial modulation of magnetization (CSPAMM) pulse sequence with two small z-encoding gradients immediately before the readouts in successive CSPAMM acquisitions, thereby adding a through-plane encoding from which through-plane motion can be computed from acquired images.
    Type: Grant
    Filed: May 4, 2006
    Date of Patent: February 24, 2009
    Assignee: John Hopkins University
    Inventors: Jerry L. Prince, Matthias Stuber, Nael Fakhry Osman, Khaled Zakarya Abd-Elmoniem
  • Publication number: 20090027051
    Abstract: Featured are methods for magnetic resonance imaging of a volume, such a volume having susceptibility-generating objects or interfaces having susceptibility mismatches therein. Such a method includes selectively visualizing one of susceptibility-generating objects or interfaces having susceptibility mismatches as hyperintense signals, where such visualizing includes controlling variable imaging parameters so as to control a geometric extent of a signal enhancing effect, m more particular aspects of the present invention, such selectively visualizing includes attenuating or essentially suppressing signals from fat and/or water, namely on-resonant water protons, so as to thereby enhance a signal(s) associated with magnetic susceptibility gradient(s). Also featured are MRI systems, apparatuses and/or applications programs for execution on a computer system controlling the MRI data acquisition process embodying such methods.
    Type: Application
    Filed: February 3, 2006
    Publication date: January 29, 2009
    Applicant: The Johns Hopkins University
    Inventors: Matthias Stuber, Wesley D. Gilson, Dara L. Kraitchman
  • Patent number: 7375520
    Abstract: A T2 preparation sequence uses a segmented BIR-4 adiabatic pulse with two substantially equal delays and is insensitive to B1 field variations and can simultaneously suppress fat signals with low specific absorption rate (SAR). An adiabatic reverse half passage pulse is applied followed by a predetermined delay. An adiabatic full passage pulse is applied followed by a substantially equal delay, followed by an adiabatic half passage pulse. Fat signal suppression is achieved by increasing or decreasing either the first delay or the second delay.
    Type: Grant
    Filed: April 20, 2006
    Date of Patent: May 20, 2008
    Assignees: The United States of America as represented by the Department of Health, Johns Hopkins University
    Inventors: Reza Nezafat, J. Andrew Derbyshire, Ronald Ouwerkerk, Matthias Stuber, Elliot R. McVeigh
  • Publication number: 20070016000
    Abstract: Three-dimensional MR motion estimation on a single image plane based on tagged MRI and HARP processing. Tagged magnetic resonance imaging technique encodes and automatically tracks displacement of spatially modulated object in three dimensions, encoding both in plane and through-plane motion in a single image plane without affecting acquisition speed. Post-processing unravels encoding in order to directly track 3-D displacement of points within the image plane throughout image sequence. The invention is particularly suited to use on a heart for tracking and determining myocardial displacement. In one embodiment, an MR pulse sequence extends a slice following complementary spatial modulation of magnetization (CSPAMM) pulse sequence with two small z-encoding gradients immediately before the readouts in successive CSPAMM acquisitions, thereby adding a through-plane encoding from which through-plane motion can be computed from acquired images.
    Type: Application
    Filed: May 4, 2006
    Publication date: January 18, 2007
    Applicant: Johns Hopkins University
    Inventors: Jerry Prince, Matthias Stuber, Nael Osman, Khaled Abd-Elmoniem
  • Publication number: 20060284615
    Abstract: A T2 preparation sequence uses a segmented BIR-4 adiabatic pulse with two substantially equal delays and is insensitive to B1 field variations and can simultaneously suppress fat signals with low specific absorption rate (SAR). An adiabatic reverse half passage pulse is applied followed by a predetermined delay. An adiabatic full passage pulse is applied followed by a substantially equal delay, followed by an adiabatic half passage pulse. Fat signal suppression is achieved by increasing or decreasing either the first delay or the second delay.
    Type: Application
    Filed: April 20, 2006
    Publication date: December 21, 2006
    Inventors: Reza Nazafat, J. Derbyshire, Ronald Ouwerkerk, Matthias Stuber, Elliot McVeigh
  • Publication number: 20060253015
    Abstract: Adiabatic pulses that define an amplitude modulation and a frequency modulation are applied in a sequence of pulses to obtain a T2 weighted magnetic resonance image. Such an adiabatic T2 prep sequence typically includes a first 90° pulse, an even number of adiabatic pulses, and a second 90° pulse. Adiabatic pulses can be selected based on function pairs, or can be defined numerically. A magnetic resonance imaging (MRI) system includes a library of adiabatic pulse waveforms, and is configured to select a waveform and apply an RF magnetic field based on the selected pulse waveform.
    Type: Application
    Filed: June 6, 2005
    Publication date: November 9, 2006
    Inventors: Reza Nezafat, Ronald Ouwerkerk, Matthias Stuber
  • Patent number: 6501979
    Abstract: This invention relates to methods and apparatus for medical imaging of parts of a patient in which imaging data acquisition is gated by a combination of electrocardiogram (ECG) and peripheral pulse (PPU) signals from the patient. The methods of the invention include obtaining ECG signals from a patient in a medical imaging apparatus, obtaining PPU signals from the patient, providing one or more synchronization signals in dependence on both the ECG signals and the PPU signals, wherein the synchronization signals indicate occurrences of pre-determined phases of the cyclic movements of the heart only if the PPU signals also indicate that the determined heart phase is physiologically possible, and controlling the medical imaging apparatus in dependence on the synchronization signals to collect imaging data synchronized with cyclic movements of the heart from the patient in the examination zone and to reconstruct a medical image of a part of the patient from the collected imaging data.
    Type: Grant
    Filed: March 9, 2000
    Date of Patent: December 31, 2002
    Assignee: Koninklijke Philips Electronics N.V.
    Inventors: Warren J. Manning, Rene M. Botnar, Matthias Stuber
  • Patent number: 6285900
    Abstract: The invention relates to a magnetic resonance method for determining a perfusion image of a portion, which method comprises the following steps: generation of a control pulse sequence in a first portion of the body and measurement of a control data set by generation of an MR-image sequence for imaging of an third portion of the body, generation of a labelling pulse sequence in a second portion of the body wherein a fluid flows towards the third portion, and measurement of the labelled data set by generation of the MR-image sequence for imaging the third portion of the body, and reconstruction of the perfusion image of the fluid in a mass of the third portion of the body from a combination of the control data set and the labelled data set.
    Type: Grant
    Filed: December 10, 1998
    Date of Patent: September 4, 2001
    Assignee: U.S. Philips Corporation
    Inventors: Matthias Stuber, Klaas P. Pruessmann, Xavier G. Golay, Markus B. Scheidegger, Peter Boesiger
  • Patent number: 6252399
    Abstract: The invention relates to a method for determining an image of a portion of a body by means of magnetic resonance (MR), which method comprises a step for rotating a magnetization of spins in a selected portion of the body and by generating an RF pulse in a selected slice. The RF pulse comprises a concatenation of a selective first RF pulse and a second selective RF pulse.
    Type: Grant
    Filed: December 10, 1998
    Date of Patent: June 26, 2001
    Assignee: U.S. Philips Corporation
    Inventors: Klaas P. Pruessmann, Matthias Stuber, Xavier G. Golay, Henryk M. Faas, Peter Boesiger
  • Patent number: 6230039
    Abstract: This invention relates to methods and apparatus for magnetic resonance (MR) imaging of moving parts of a patient in which flip angles for the excitation of nuclear magnetization are adaptively selected during image data acquisition in order to minimize artifacts. In particular, the flip angles are selected so that a smooth distribution of signal-strengths in k-space results even though the order of phase-encoding gradients is also adaptively selected in dependence of the measured instantaneous state of motion of the moving part. The invention also includes MR apparatus for practicing the described methods and software for controlling an MR apparatus to practice the methods.
    Type: Grant
    Filed: March 28, 2000
    Date of Patent: May 8, 2001
    Assignee: Philips Electronics North America Corporation
    Inventors: Matthias Stuber, Rene Botnar