Patents by Inventor Matthias Treu

Matthias Treu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 3- (AMINOMETHYLIDEN) 2-INDOLINONE DERIVATES AND THEIR USE AS CELL PROLIFERATION INHIBITORS
    Publication number: 20090105216
    Abstract: The present invention encompasses compounds of general formula (1) wherein R1, R2, R3 and X are defined as in claim 1, which are suitable for the treatment of diseases characterised by excessive or abnormal cell proliferation, and the use thereof for preparing a pharmaceutical composition having the above-mentioned properties.
    Type: Application
    Filed: April 23, 2007
    Publication date: April 23, 2009
    Inventors: Matthias Treu, Andreas Mantoulidis, Ulrike Tontsch-Grunt
  • 2,4-diamino-pyrimidines as aurora inhibitors
    Publication number: 20070032514
    Abstract: The present invention encompasses compounds of general formula (1) wherein R1 to R3 are defined as in claim 1, which are suitable for the treatment of diseases characterised by excessive or abnormal cell proliferation, and the use thereof for preparing a pharmaceutical composition having the above-mentioned properties.
    Type: Application
    Filed: June 27, 2006
    Publication date: February 8, 2007
    Inventors: Stephan Zahn, Guido Boehmelt, Andreas Mantoulidis, Ulrich Reiser, Matthias Treu, Ulrich Guertler, Andreas Schoop, Flavio Solca, Ulrike Tontsch-Grunt, Ralph Brueckner, Charlotte Reither, Lars Herfurth, Oliver Kraemer, Heinz Stadtmueller, Harald Engelhardt
  • Derivatives and analogs of galanthamine
    Publication number: 20070027138
    Abstract: New compounds of general formula I
    Type: Application
    Filed: June 28, 2006
    Publication date: February 1, 2007
    Inventors: Ulrich Jordis, Johannes Frohlich, Matthias Treu, Manfred Hirnschall, Laszlo Czollner, Beate Kalz, Stefan Welzig
  • Derivatives and analogs of galanthamine
    Patent number: 7166588
    Abstract: New compounds of general formula I
    Type: Grant
    Filed: May 22, 2001
    Date of Patent: January 23, 2007
    Assignee: Sanochemia Pharmazeutika Aktiengesellschaft
    Inventors: Ulrich Jordis, Johannes Frohlich, Matthias Treu, Manfred Hirnschall, Laszlo Czollner, Beate Kälz, Stefan Welzig
  • Alpha-Carbolines as CDK-1 inhibitors
    Publication number: 20070004684
    Abstract: The present invention encompasses compounds of general formula (1) wherein R2 to R5 and X are defined as in claim 1, which are suitable for the treatment of diseases characterised by excessive or abnormal cell proliferation, and the use thereof for preparing a pharmaceutical composition having the above-mentioned properties.
    Type: Application
    Filed: June 8, 2006
    Publication date: January 4, 2007
    Applicant: Boehringer Ingelheim International GmbH
    Inventors: Peter Sennhenn, Andreas Mantoulidis, Matthias Treu, Ulrike Tontsch-Grunt, Walter Spevak, Darryl McConnell, Andreas Schoop, Ralph Brueckner, Albrecht Jacobi, Ulrich Guertler, Gisela Schnapp, Christian Klein, Frank Himmelsbach, Alexander Pautsch, Bodo Betzmeier, Lars Herfurth, Juergen Mack, Dieter Wiedenmayer, Gerd Bader, Ulrich Reiser
  • Methods for producing norgalanthamine, as well as isomers, salts and hydrates thereof
    Publication number: 20060069251
    Abstract: The invention relates to processes, which can be performed on an industrial scale, for the production of norgalanthamine, norgalanthamine derivatives and isomers thereof of general formula (A) as well as salts or hydrates thereof with general formula (B). As processes for the production of compounds with general formula (A) or (B), an oxidative demethylation and a catalytic demethylation of the corresponding galanthamine compounds are indicated.
    Type: Application
    Filed: January 9, 2003
    Publication date: March 30, 2006
    Inventors: Ulrich Jordis, Matthias Treu, Manfred Hirnschall, Johannes Frohlich, Laszlo Crollner, Beate Kalz, Thomas Kalz, Peter Kuhnhackl
  • Pyrrolobenzimidazolones and their use as anti-proliferative agents
    Publication number: 20050261350
    Abstract: The invention relates to pyrrolobenzimidazolone compounds of formula (I), wherein A, T and R1 to R3 are defined as in claim 1, which are suitable for the treatment of diseases characterized by excessive or abnormal cell proliferation and the use thereof for preparing a pharmaceutical composition.
    Type: Application
    Filed: May 17, 2005
    Publication date: November 24, 2005
    Applicant: Boehringer Ingelheim International GmbH
    Inventors: Darryl McConnel, Steffen Steurer, Bernd Krist, Ulrike Weyer-Czernilofsky, Maria Impagnatiello, Matthias Treu, Iris Kauffmann-Hefner, Pilar Garin-Chesa, Andreas Schnapp
  • Novel derivatives and analogues of galanthamin
    Publication number: 20030199493
    Abstract: New compounds of general formula I 1
    Type: Application
    Filed: March 18, 2002
    Publication date: October 23, 2003
    Inventors: Ulrich Jordis, Johannes Frohlich, Matthias Treu, Manfred Hirnschall, Laszlo Czollner, Beate Kalz, Stefan Welzig