Patents by Inventor Matthias Vennemann

Matthias Vennemann has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 8969401
    Abstract: Compounds of a certain formula (I), in which R1, R2, R3, R4, R5, R6 and R7 have the meanings indicated in the description, are novel effective HDAC inhibitors.
    Type: Grant
    Filed: November 20, 2012
    Date of Patent: March 3, 2015
    Assignee: 4SC AG
    Inventors: Thomas Maier, Thomas Beckers, Thomas Baer, Petra Gimmnich, Frank Dullweber, Matthias Vennemann
  • Patent number: 8957064
    Abstract: Compounds of formula (I) or an N-oxide, a salt, a tautomer or a stereoisomer of said compound, or a salt of said N-oxide, tautomer or stereoisomer, wherein ring B and the pyrimidine to which it is fused, R4, R5, R6, R7, m and n have the meanings as given in the description and the claims, which are effective inhibitors of the Pi3K/Akt pathway, processes for their production and their use as pharmaceuticals.
    Type: Grant
    Filed: February 2, 2010
    Date of Patent: February 17, 2015
    Assignee: Bayer Intellectual Property GmbH
    Inventors: Matthias Vennemann, Thomas Bär, Thomas Maier, Swen Hölder, Gerrit Beneke, Florian Dehmel, Armin Zülch, Andreas Strub, Stuart Ince, Hartmut Rehwinkel, Ningshu Liu, Ulf Bömer, Barbara Beckers
  • Patent number: 8614218
    Abstract: Compounds of formula (I) a tautomer or stereoisomer thereof, or a salt thereof, wherein ring B and the pyrimidine to which it is fused, R4, R5, R6 and R7 have the meanings as given in the description and the claims, are effective inhibitors of the Pi3K/Akt pathway.
    Type: Grant
    Filed: March 25, 2010
    Date of Patent: December 24, 2013
    Assignee: Bayer Intellectual Property GmbH
    Inventors: Swen Hölder, Matthias Vennemann, Gerrit Beneke, Armin Zülch, Volker Gekeler, Thomas Beckers, Astrid Zimmermann, Hemant Joshi
  • Patent number: 8530493
    Abstract: Compounds of a certain formula I, in which R1, R2, R3, R4, R5 and R6 have the meanings indicated in the description, are effective compounds with anti-proliferative and/or apoptosis inducing activity.
    Type: Grant
    Filed: February 21, 2007
    Date of Patent: September 10, 2013
    Assignee: 4SC AG
    Inventors: Matthias Vennemann, Thomas Bãr, Jürgen Braunger, Astrid Zimmermann, Volker Gekeler
  • Patent number: 8440830
    Abstract: The compounds of formula (I), wherein ring D and ring E together form a fused ring system selected from formula (II), (III), (IV), (V), (VI), (VII), and the salts of these compounds are novel, effective inhibitors of histone deacetylases.
    Type: Grant
    Filed: September 19, 2008
    Date of Patent: May 14, 2013
    Assignee: 4SC AG
    Inventors: Thomas Maier, Thomas Beckers, Thomas Baer, Matthias Vennemann, Volker Gekeler, Astrid Zimmermann, Petra Gimmnich, Kamlesh Padiya, Hemant Joshi, Uday Joshi, Mahindra Makhija, Dipak Harel
  • Patent number: 8399505
    Abstract: Compounds of a certain formula (I), in which R1, R2, R3, R4, R5, R6 and R7 have the meanings indicated in the description, are novel effective HDAC inhibitors.
    Type: Grant
    Filed: June 24, 2010
    Date of Patent: March 19, 2013
    Assignee: 4SC AG
    Inventors: Thomas Maier, Thomas Beckers, Thomas Baer, Petra Gimmnich, Frank Dullweber, Matthias Vennemann
  • Patent number: 8067615
    Abstract: Compounds of a certain formula (I), in which R1, R2, R3, R4, R5, R6 and R7 have the meanings indicated in the description, are novel effective HDAC inhibitors.
    Type: Grant
    Filed: June 24, 2010
    Date of Patent: November 29, 2011
    Assignee: 4SC AG
    Inventors: Thomas Maier, Thomas Beckers, Thomas Baer, Petra Gimmnich, Frank Dullweber, Matthias Vennemann
  • Patent number: 8044065
    Abstract: Compounds of a certain formula I, in which R1, R2, R3, R4 and X have the meanings indicated in the description, are novel effective compounds with Eg5 inhibitory, anti-proliferative and/or apoptosis inducing activity.
    Type: Grant
    Filed: March 30, 2010
    Date of Patent: October 25, 2011
    Assignee: Altana Pharma AG
    Inventors: Matthias Vennemann, Thomas Baer, Gudrun Groegor
  • Publication number: 20110166140
    Abstract: Compounds of a certain formula (I), in which R1, R2, R3, R4, R5, R6 and R7 have the meanings indicated in the description, are novel effective HDAC inhibitors.
    Type: Application
    Filed: March 14, 2011
    Publication date: July 7, 2011
    Inventors: Thomas MAIER, Thomas BECKERS, Thomas BAER, Petra GIMMNICH, Frank DULLWEBER, Matthias VENNEMANN
  • Publication number: 20110091889
    Abstract: The present invention provides a centrosome assay for the identification of preferably, Eg5 inhibitors.
    Type: Application
    Filed: March 24, 2009
    Publication date: April 21, 2011
    Applicant: 4SC AG
    Inventors: Claudia Diefenbach, Matthias Vennemann, Astrid Grunwald
  • Publication number: 20110027226
    Abstract: Compounds of a certain formula I, in which R1, R2, R3 and R4 have the meanings indicated in the description, are effective Eg5-inhibiting compounds with anti-proliferative and/or apoptosis inducing activity.
    Type: Application
    Filed: August 22, 2007
    Publication date: February 3, 2011
    Applicant: 4SC AG
    Inventors: Matthias Vennemann, Juergen Braugner, Petra Gimmnich, Thomas Baer
  • Publication number: 20110021494
    Abstract: The compounds of formula (I), wherein ring D and ring E together form a fused ring system selected from formula (II), (III), (IV), (V), (VI), (VII), and the salts of these compounds are novel, effective inhibitors of histone deacetylases.
    Type: Application
    Filed: September 19, 2008
    Publication date: January 27, 2011
    Applicant: 4SC AG
    Inventors: Thomas Maier, Thomas Beckers, Thomas Baer, Matthias Vennemann, Volker Gekeler, Astrid Zimmermann, Petra Gimmnich, Kamlesh Padiya, Hemant Joshi, Uday Joshi, Mahindra Makhija, Dipak Harel
  • Patent number: 7842820
    Abstract: Compounds of the formula I in which the substitutents have the definitions provided in the specification, are novel, effective HDAC inhibitors.
    Type: Grant
    Filed: March 10, 2005
    Date of Patent: November 30, 2010
    Assignee: 4SC AG
    Inventors: Thomas Maier, Thomas Beckers, Thomas Baer, Petra Gimmnich, Frank Dullweber, Matthias Vennemann
  • Publication number: 20100261721
    Abstract: Compounds of a certain formula (I), in which R1, R2, R3, R4, R5, R6 and R7 have the meanings indicated in the description, are novel effective HDAC inhibitors.
    Type: Application
    Filed: June 24, 2010
    Publication date: October 14, 2010
    Inventors: Thomas MAIER, Thomas Beckers, Thomas Baer, Petra Gimmnich, Frank Dullweber, Matthias Vennemann
  • Publication number: 20100261761
    Abstract: Compounds of a certain formula (I), in which R1, R2, R3, R4, R5, R6 and R7 have the meanings indicated in the description, are novel effective HDAC inhibitors.
    Type: Application
    Filed: June 24, 2010
    Publication date: October 14, 2010
    Inventors: Thomas Maier, Thomas Beckers, Thomas Baer, Petra Gimmnich, Frank Dullweber, Matthias Vennemann
  • Patent number: 7776864
    Abstract: Compounds of formula (I) a tautomer or stereoisomer thereof, or a salt thereof, wherein ring B and the pyrimidine to which it is fused, R4, R5, R6 and R7 have the meanings as given in the description and the claims, are effective inhibitors of the Pi3K/Akt pathway.
    Type: Grant
    Filed: August 14, 2008
    Date of Patent: August 17, 2010
    Assignee: Bayer Schering Pharma AG
    Inventors: Swen Hölder, Matthias Vennemann, Gerrit Beneke, Armin Zülch, Volker Gekeler, Thomas Beckers, Astrid Zimmermann, Hemant Joshi
  • Publication number: 20100183550
    Abstract: Compounds of a certain formula I, in which R1, R2, R3, R4 and X have the meanings indicated in the description, are novel effective compounds with Eg5 inhibitory, anti-proliferative and/or apoptosis inducing activity.
    Type: Application
    Filed: March 30, 2010
    Publication date: July 22, 2010
    Inventors: Matthias VENNEMANN, Thomas Baer, Gudrun Groegor
  • Publication number: 20100184782
    Abstract: Compounds of formula (I) a tautomer or stereoisomer thereof, or a salt thereof, wherein ring B and the pyrimidine to which it is fused, R4, R5, R6 and R7 have the meanings as given in the description and the claims, are effective inhibitors of the Pi3K/Akt pathway.
    Type: Application
    Filed: March 25, 2010
    Publication date: July 22, 2010
    Inventors: Swen Hölder, Matthias Vennemann, Gerrit Beneke, Armin Zülch, Volker Gekeler, Thomas Beckers, Astrid Zimmermann, Hemant Joshi
  • Patent number: 7718665
    Abstract: Compounds of the formula (1) in which R1, R2, R3, R4 and X have the meanings indicated in the description, are novel effective compounds with Eg5 inhibitory, anti-proliferative and/or apoptosis inducing activity.
    Type: Grant
    Filed: August 17, 2005
    Date of Patent: May 18, 2010
    Assignee: 4SC AG
    Inventors: Matthias Vennemann, Thomas Baer, Gudrun Groegor, Jürgen Braunger, Petra Gimmnich, Thomas Maier, Heike Rothfels
  • Publication number: 20100104659
    Abstract: Compounds of a certain formula I, in which Ra, Rb and Rc have the meanings indicated in the description, are effective compounds with anti-proliferative and/or apoptosis inducing activity.
    Type: Application
    Filed: July 12, 2007
    Publication date: April 29, 2010
    Inventors: Matthias Vennemann, Thomas Bär, Thomas Maier, Andreas Lindenmaier, Jürgen Braunger, Markus Boehm, Astrid Zimmermann, Volker Gekeler