Patents by Inventor Matthias W. Rath

Matthias W. Rath has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20140017225
    Abstract: The invention discloses identification and therapeutic use of matrix metalloproteinase oligopeptides, SEQ ID wherein the matrix metalloproteinase oligopeptide is at least one of SEQ ID 7, 11, 12, 18 and 19 and combination thereof. These oligopeptides are bound to antibodies to create an immune response in the subject mammal against the matrix metalloproteinases of various diseases. The instance method is a means of therapeutic intervention against the disease spread created by the matrix metalloproteinases. Further use of these oligopeptide-antibody responses can be extended to any and all diseases that use the matrix metalloproteinases to aid in their pathogenicity.
    Type: Application
    Filed: April 10, 2013
    Publication date: January 16, 2014
    Inventor: MATTHIAS W. RATH
  • Publication number: 20140017267
    Abstract: The invention discloses identification and therapeutic use of matrix metalloproteinase oligopeptides, SEQ ID 5-SEQ ID 21. These oligopeptides are bound to antibodies to create an immune response in the subject mammal against the matrix metalloproteinases of various diseases. This is a means of therapeutic intervention against the disease spread created by the matrix metalloproteinases. Further use of these oligopeptide-antibody responses can be extended to any and all diseases that use the matrix metalloproteinases to aid in their pathogenicity.
    Type: Application
    Filed: January 11, 2013
    Publication date: January 16, 2014
    Inventor: Matthias W Rath
  • Publication number: 20130040273
    Abstract: Several methods, processes and system for modular tool as an integrated multimedia tool system to explore and study the virtual human body is disclosed. Content and context modules allow for scientific gaming using modular multimedia objects, social media and different configurations. The disclosure allows an individual to travel through the virtual human body in a self guided and interactive tour. It specifically enables the user to learn the structure and function of different organs, different types of cells, intercellular space as well as different cellular organelles etc. Further, the system may be used by the local authority as an electronic study tool for seamless integrated mode of delivering the educational tool suited to the local curriculum. This may also serve as a tool for patients, doctors, focus groups and student to explore and learn about the pathological and physiological conditions in a human body.
    Type: Application
    Filed: August 13, 2011
    Publication date: February 14, 2013
    Inventors: Matthias W. Rath, Aleksandra Niedzwiecki
  • Publication number: 20130040274
    Abstract: A novel integrated system and method for visualizing human physiology, disease and treatment options are described in the instant application. The graphical rendering of the human body is in depth and the user can explore the internal workings of the organs and cells by simply performing a pealing like act using a cursor and the layer as a flap opens up to show the details. A user can click on a specific topic and watch a video, narration or text relevant to the topic of choice. The integrated system provides storage of curated data, social media access and interaction, database storage and analytics to calculate user behavior. This technology may used as an application on any mobile and hardware device.
    Type: Application
    Filed: June 18, 2012
    Publication date: February 14, 2013
    Inventors: MATTHIAS W. RATH, Aleksandra Niedzwiecki, Markus Haecki
  • Publication number: 20130011423
    Abstract: The invention discloses identification and therapeutic use of matrix metalloproteinase oligopeptides, SEQID 5-SEQID 21. These oligopeptides are bound to antibodies to create an immune response in the subject mammal against the matrix metalloproteinases of various diseases. This is a means of therapeutic intervention against the disease spread created by the matrix metalloproteinases. Further use of these oligopeptide-antibody responses can be extended to any and all diseases that use the matrix metalloproteinases to aid in their pathogenicity.
    Type: Application
    Filed: July 13, 2012
    Publication date: January 10, 2013
    Inventors: Matthias W. Rath, Aleksandra Niedzwiecki, Waheed M. Roomi
  • Publication number: 20120321656
    Abstract: The invention discloses identification, method of making and therapeutic use of synthetic oligopeptides for the treatment of infectious diseases, in particular tuberculosis. The oligopeptides are designed using virulence mediating protein for Mycobacterium Tuberculosis bacteria. The antibodies may be used for diagnostic and treatment purposes of infectious diseases. In particular, the sequences with SEQ ID 1 to 11 may be used to produce such oligopeptides synthetically. Suppression of activity of mycobacterium tuberculosis may be achieved with oligopeptides analogous to SEQ ID 1 to 11 as a therapeutic drug and/or as a vaccine in a mammal.
    Type: Application
    Filed: June 15, 2012
    Publication date: December 20, 2012
    Inventors: MATTHIAS W. RATH, ALEKSANDRA NIEDZWIECKI
  • Patent number: 8067009
    Abstract: The invention discloses identification and therapeutic use of matrix metalloproteinase oligopeptides and peptidomimetics. The oligopeptides are used for making antibodies. The antibodies are used for diagnostic and treatment purposes of various diseases. In particular, the diseases may involve the mechanism of degradation of extracellular matrix by MMP's during cell proliferation cycle. Suppression of MMP activity seems to arrest tumor growth during cancer progression. MMP oligopeptides were used as vaccines to treat mice having murine melanoma B16FO induced tumor. There was a significant drop in tumor weight and size for the group of mice that were immunized with MMP oligopeptide.
    Type: Grant
    Filed: June 14, 2011
    Date of Patent: November 29, 2011
    Inventors: Matthias W Rath, Aleksandra Niedzwiecki, Waheed M Roomi
  • Patent number: 8003110
    Abstract: The invention discloses identification and therapeutic use of matrix metalloproteinase oligopeptides and peptidomimetics. The oligopeptides are used for making antibodies. The antibodies are used for diagnostic and treatment purposes of various diseases. In particular, the diseases may involve the mechanism of degradation of extracellular matrix by MMP's during cell proliferation cycle. Suppression of MMP activity seems to arrest tumor growth during cancer progression. MMP oligopeptides were used as vaccines to treat mice having murine melanoma B16FO induced tumor. There was a significant drop in tumor weight and size for the group of mice that were immunized with MMP oligopeptide.
    Type: Grant
    Filed: January 24, 2011
    Date of Patent: August 23, 2011
    Inventors: Matthias W Rath, Aleksandra Niedzwiecki, Waheed M Roomi
  • Patent number: 5278189
    Abstract: A method is provided for prevention and treatment of cardiovascular disease, such as atherosclerosis, by administering therapeutically effective dosages of a drug comprised of ascorbate, lipoprotein(a) binding inhibitors, and antioxidants.
    Type: Grant
    Filed: July 24, 1990
    Date of Patent: January 11, 1994
    Inventors: Matthias W. Rath, Linus C. Pauling
  • Patent number: 5230996
    Abstract: A method and pharmaceutical agent are provided for the prevention and treatment of cardiovascular disease, particularly cardiovascular disease in the context of diabetic angiopathy, by-pass surgery, organ transplantation, and hemodialysis, by administering ascorbate and substances that inhibit the binding of lipoprotein (a) to blood vessel walls. The use of ascorbate and lipoprotein (a) binding inhibitors such as tranexamic acid in a temporary storage solution for blood vessels and organs prior to transplantation is also demonstrated.
    Type: Grant
    Filed: July 24, 1990
    Date of Patent: July 27, 1993
    Assignee: Therapy 2000
    Inventors: Matthias W. Rath, Linus C. Pauling