Abstract: A process for the solvent-free and mastication-free production of a self-adhesive composition which is based on SBC and comprises a pharmaceutically active substance, in a continuously operating apparatus which comprises a feeding section and a compounding section. The SBC is added to the feeding section and the pharmaceutically active substance is added to the feed section and/or the compounding section, and the composition is homogenized in the compounding section.

Abstract: An active substance matrix patch for controlled delivery of at least one hyperemic active substance to the skin, comprising a flexible cover layer and a water insoluble, pressure sensitive adhesive active substance matrix, wherein said adhesive matrix is free from mineral oils and tackifier resins and comprising: a) from 25 to 90% by weight of synthetic framework polymers based on polyisobutylene, b) from 5 to 40% by weight of amorphous poly-?-olefin, c) from 10 to 60% by weight of an insoluble hydrophilic filler having an average particle size of less than 100 ?m, and d) from 0.001 to 20% by weight of the hyperemic active substance.

Abstract: An active ingredient containing bandage for the controlled delivery of a pharmaceutically active ingredient to the skin. The bandage comprises a flexible cover layer and a water-insoluble, adhesive styrene block copolymer (SBC)-based matrix that comprises at least 34% by weight of the pharmaceutically active ingredient.

Abstract: A process for the solvent-free and mastication-free production of a self-adhesive composition which is based on SBC and comprises a pharmaceutically active substance, in a continuously operating apparatus which comprises a feeding section and a compounding section. The SBC is added to the feeding section and the pharmaceutically active substance is added to the feed section and/or the compounding section, and the composition is homogenized in the compounding section.

Abstract: An active substance patch comprising a laminate coated on its skin-facing side with an adhesive comprising an active substance. In one embodiment, the laminate has at least two layers. More particularly, in this embodiment, the side of the laminate remote from the skin includes a barrier layer that is impermeable to the active substance, and the skin-facing side of the laminate includes a backing layer. These two layers are preferably configured so that they can be separated from one another by a user.

Abstract: An active substance matrix patch for controlled delivery of at least one hyperemic active substance to the skin, comprising a flexible cover layer and a water insoluble, pressure sensitive adhesive active substance matrix, wherein said adhesive matrix is free from mineral oils and tackifier resins and comprising:

Abstract: A self-adhesive backing assembly for medical use having a backing to which an adhesive coating is applied. In one embodiment of the invention, the backing assembly includes an aluminum layer between the backing and the adhesive coating.

Abstract: Active substance plasters consisting of a backing material and an at least partially applied adhesive composition, characterized in that a component comprising one or more active substances is additionally applied in the form of spun fibres or filaments to the backing material, this component having an at least partly thermoplastic basis.

Abstract: An active substance matrix patch for controlled delivery of nonsteroidal antirheumatics to the skin, comprising a flexible cover layer and a water insoluble, pressure sensitively adhesive active substance matrix, wherein said adhesive matrix is free from mineral oils and tackifier resins and is composed of a) from 25 to 90% by weight of synthetic framework polymers based on polyisobutylene, b) from 5 to 40% by weight of amorphous poly-&agr;-olefin, c) from 10 to 60% by weight of an insoluble hydrophilic filler having an average particle size of less than 100 &mgr;m, and d) from 0.001 to 20% by weight of a drug.

Abstract: A process for the continuous solvent-free and mastication-free production of self-adhesive compositions based on polyisobutylene with at least one active pharmaceutical substance in a continuously operating apparatus having a filling section and a compounding section, comprising the following steps: a) feeding an initial batch comprising granulated polyisobutylene, at least one release auxiliary and at least one active pharmaceutical substance into the filling section of the apparatus;  if desired, feeding low molecular mass polyisobutylene, fillers, plasticizers, tackifiers and/or resins, b) transferring the feed components of the self-adhesive composition from the filling section to the compounding section, c) if desired, adding the components of the self-adhesive composition that have not been introduced in the filling section, such as low molecular mass polyisobutylene, fillers, plasticizers, tackifiers and/or resins, to the compounding section, d) if desired, adding further pharmaceutical subst

Abstract: Use of auxiliaries to improve the release of ibuprofen from hot melt adhesive compositions.

Abstract: Plasters containing active substance, comprising a backing material and, applied thereon, a hot-melt self-adhesive composition, characterized in that the hot-melt self-adhesive composition comprises at least one hyper-aemic active substance.

Abstract: An active substance matrix patch for controlled delivery of nonsteroidal antirheumatics to the skin, comprising a flexible cover layer and a water insoluble, pressure sensitively adhesive active substance matrix, wherein said adhesive matrix is free from mineral oils and tackifier resins and is composed of

Abstract: A process for the continuous solvent-free and mastication-free production of self-adhesive compositions based on polyisobutylene with at least one active pharmaceutical substance in a continuously operating apparatus having a filling section and a compounding section, comprising the following steps:

Abstract: Active substance plasters comprising a backing material and, applied at least partially thereon, an adhesive composition, whereina) the adhesive composition comprises at least on active substance,b) the adhesive composition is a hotmelt adhesive composition, andc) the adhesive composition is foamed.