Patents by Inventor Matthias Willmann

Matthias Willmann has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11612659
    Abstract: Anti-CD40 antibodies are formulated as lyophilisate or liquid formulation. The lyophilisates can be reconstituted to give a solution with a high concentration of the antibody active ingredient for delivery to a patient without high levels of antibody aggregation. The lyophilisate can be reconstituted with an aqueous reconstituent to provide an aqueous composition in which the antibody has a concentration of at least 50 mg/ml. The lyophilisate or aqueous pharmaceutical composition may include one or more of a sugar, a buffering agent, a surfactant, and/or a free amino acid.
    Type: Grant
    Filed: January 30, 2020
    Date of Patent: March 28, 2023
    Inventors: Claudia Mueller, Matthias Willmann
  • Publication number: 20220120749
    Abstract: A pharmaceutical composition is for prophylaxis and/or treatment of an infection of the cervix with human papillomavirus (HPV). A method carried out ex vivo is for predicting the probability of cure of HPV infection of the cervix. A biomarker is for predicting the emergence and/or development of cervical in-traepithelial neoplasia and/or cervical carcinoma and the likelihood of cure of cervical infection with HPV. Another method is for prophylaxis and/or treatment of cervical infection with HPV.
    Type: Application
    Filed: December 29, 2021
    Publication date: April 21, 2022
    Inventors: Matthias WILLMANN, Thomas Iftner
  • Publication number: 20200397903
    Abstract: Anti-CD40 antibodies are formulated as lyophilisate or liquid formulation. The lyophilisates can be reconstituted to give a solution with a high concentration of the antibody active ingredient for delivery to a patient without high levels of antibody aggregation. The lyophilisate can be reconstituted with an aqueous reconstituent to provide an aqueous composition in which the antibody has a concentration of at least 50 mg/ml. The lyophilisate or aqueous pharmaceutical composition may include one or more of a sugar, a buffering agent, a surfactant, and/or a free amino acid.
    Type: Application
    Filed: January 30, 2020
    Publication date: December 24, 2020
    Applicant: Novartis AG
    Inventors: Claudia MUELLER, Matthias WILLMANN
  • Patent number: 10588976
    Abstract: Anti-CD40 antibodies are formulated as lyophilisate or liquid formulation. The lyophilisates can be reconstituted to give a solution with a high concentration of the antibody active ingredient for delivery to a patient without high levels of antibody aggregation. The lyophilisate can be reconstituted with an aqueous reconstituent to provide an aqueous composition in which the antibody has a concentration of at least 50 mg/ml. The lyophilisate or aqueous pharmaceutical composition may include one or more of a sugar, a buffering agent, a surfactant, and/or a free amino acid.
    Type: Grant
    Filed: September 26, 2018
    Date of Patent: March 17, 2020
    Assignee: Novartis AG
    Inventors: Claudia Mueller, Matthias Willmann
  • Publication number: 20190151450
    Abstract: Anti-CD40 antibodies are formulated as lyophilisate or liquid formulation. The lyophilisates can be reconstituted to give a solution with a high concentration of the antibody active ingredient for delivery to a patient without high levels of antibody aggregation. The lyophilisate can be reconstituted with an aqueous reconstituent to provide an aqueous composition in which the antibody has a concentration of at least 50 mg/ml. The lyophilisate or aqueous pharmaceutical composition may include one or more of a sugar, a buffering agent, a surfactant, and/or a free amino acid.
    Type: Application
    Filed: September 26, 2018
    Publication date: May 23, 2019
    Applicant: Novartis AG
    Inventors: Claudia MUELLER, Matthias WILLMANN
  • Patent number: 10254085
    Abstract: A device for arranging an accessory on a firearm, in particular a handgun, is provided, wherein the device has a housing for receiving the accessory in the housing, wherein the housing can be fastened to the firearm, wherein the housing has a first portion with a front end wall and with a rear end wall at a distance from the front end wall, the housing has a second portion, which protrudes axially at the rear end wall of the first portion, the second portion has a fastening device for fastening the housing to the firearm, and the housing has a substantially L-shaped basic form. A firearm with a device for arranging an accessory on a firearm that is arranged on it or can be arranged on it is also provided.
    Type: Grant
    Filed: August 18, 2017
    Date of Patent: April 9, 2019
    Inventor: Matthias Willmann
  • Patent number: 10111958
    Abstract: Anti-CD40 antibodies are formulated as lyophilizate or liquid formulation. The lyophilizates can be reconstituted to give a solution with a high concentration of the antibody active ingredient for delivery to a patient without high levels of antibody aggregation. The lyophilizate can be reconstituted with an aqueous reconstituent to provide an aqueous composition in which the antibody has a concentration of at least 50 mg/ml. The lyophilizate or aqueous pharmaceutical composition may include one or more of a sugar, a buffering agent, a surfactant, and/or a free amino acid.
    Type: Grant
    Filed: January 26, 2018
    Date of Patent: October 30, 2018
    Assignee: Novartis AG
    Inventors: Claudia Mueller, Matthias Willmann
  • Publication number: 20180169246
    Abstract: Anti-CD40 antibodies are formulated as lyophilisate or liquid formulation. The lyophilisates can be reconstituted to give a solution with a high concentration of the antibody active ingredient for delivery to a patient without high levels of antibody aggregation. The lyophilisate can be reconstituted with an aqueous reconstituent to provide an aqueous composition in which the antibody has a concentration of at least 50 mg/ml. The lyophilisate or aqueous pharmaceutical composition may include one or more of a sugar, a buffering agent, a surfactant, and/or a free amino acid.
    Type: Application
    Filed: January 26, 2018
    Publication date: June 21, 2018
    Applicant: Novartis AG
    Inventors: Claudia MUELLER, Matthias WILLMANN
  • Publication number: 20170370679
    Abstract: A device for arranging an accessory on a firearm, in particular a handgun, is provided, wherein the device has a housing for receiving the accessory in the housing, wherein the housing can be fastened to the firearm, wherein the housing has a first portion with a front end wall and with a rear end wall at a distance from the front end wall, the housing has a second portion, which protrudes axially at the rear end wall of the first portion, the second portion has a fastening device for fastening the housing to the firearm, and the housing has a substantially L-shaped basic form. A firearm with a device for arranging an accessory on a firearm that is arranged on it or can be arranged on it is also provided.
    Type: Application
    Filed: August 18, 2017
    Publication date: December 28, 2017
    Inventor: Matthias Willmann
  • Publication number: 20150086559
    Abstract: Anti-CD40 antibodies are formulated as lyophilisate or liquid formulation. The lyophilisates can be reconstituted to give a solution with a high concentration of the antibody active ingredient for delivery to a patient without high levels of antibody aggregation. The lyophilisate can be reconstituted with an aqueous reconstituent to provide an aqueous composition in which the antibody has a concentration of at least 50 mg/ml. The lyophilisate or aqueous pharmaceutical composition may include one or more of a sugar, a buffering agent, a surfactant, and/or a free amino acid.
    Type: Application
    Filed: May 2, 2013
    Publication date: March 26, 2015
    Applicant: NOVARTIS AG
    Inventors: Claudia Mueller, Matthias Willmann
  • Publication number: 20140004131
    Abstract: Anti-CD40 antibodies are formulated as lyophilisate or liquid formulation. The lyophilisates can be reconstituted to give a solution with a high concentration of the antibody active ingredient for delivery to a patient without high levels of antibody aggregation. The lyophilisate can be reconstituted with an aqueous reconstituent to provide an aqueous composition in which the antibody has a concentration of at least 50 mg/ml. The lyophilisate or aqueous pharmaceutical composition may include one or more of a sugar, a buffering agent, a surfactant, and/or a free amino acid.
    Type: Application
    Filed: April 30, 2013
    Publication date: January 2, 2014
    Applicant: NOVARTIS AG
    Inventors: Claudia Mueller, Matthias Willmann
  • Patent number: 8618172
    Abstract: The present invention relates to a solid oral dosage form comprising a therapeutically effective amount of aliskiren or a pharmaceutically acceptable salt thereof, a therapeutically effective amount of HCTZ and a hydrophilic filler selected from the group a carbohydrate or combinations thereof, e.g. sugars, sugar alcohols and starches or combinations of these.
    Type: Grant
    Filed: June 21, 2007
    Date of Patent: December 31, 2013
    Assignee: Novartis AG
    Inventor: Matthias Willmann
  • Publication number: 20090203679
    Abstract: The present invention relates to a solid oral dosage form comprising a therapeutically effective amount of aliskiren or a pharmaceutically acceptable salt thereof, a therapeutically effective amount of HCTZ and a hydrophilic filler selected from the group a carbohydrate or combinations thereof, e.g. sugars, sugar alcohols and starches or combinations of these.
    Type: Application
    Filed: June 21, 2007
    Publication date: August 13, 2009
    Inventor: Matthias Willmann