Patents by Inventor Matthias Willmann
Matthias Willmann has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11612659Abstract: Anti-CD40 antibodies are formulated as lyophilisate or liquid formulation. The lyophilisates can be reconstituted to give a solution with a high concentration of the antibody active ingredient for delivery to a patient without high levels of antibody aggregation. The lyophilisate can be reconstituted with an aqueous reconstituent to provide an aqueous composition in which the antibody has a concentration of at least 50 mg/ml. The lyophilisate or aqueous pharmaceutical composition may include one or more of a sugar, a buffering agent, a surfactant, and/or a free amino acid.Type: GrantFiled: January 30, 2020Date of Patent: March 28, 2023Inventors: Claudia Mueller, Matthias Willmann
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Publication number: 20220120749Abstract: A pharmaceutical composition is for prophylaxis and/or treatment of an infection of the cervix with human papillomavirus (HPV). A method carried out ex vivo is for predicting the probability of cure of HPV infection of the cervix. A biomarker is for predicting the emergence and/or development of cervical in-traepithelial neoplasia and/or cervical carcinoma and the likelihood of cure of cervical infection with HPV. Another method is for prophylaxis and/or treatment of cervical infection with HPV.Type: ApplicationFiled: December 29, 2021Publication date: April 21, 2022Inventors: Matthias WILLMANN, Thomas Iftner
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Publication number: 20200397903Abstract: Anti-CD40 antibodies are formulated as lyophilisate or liquid formulation. The lyophilisates can be reconstituted to give a solution with a high concentration of the antibody active ingredient for delivery to a patient without high levels of antibody aggregation. The lyophilisate can be reconstituted with an aqueous reconstituent to provide an aqueous composition in which the antibody has a concentration of at least 50 mg/ml. The lyophilisate or aqueous pharmaceutical composition may include one or more of a sugar, a buffering agent, a surfactant, and/or a free amino acid.Type: ApplicationFiled: January 30, 2020Publication date: December 24, 2020Applicant: Novartis AGInventors: Claudia MUELLER, Matthias WILLMANN
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Patent number: 10588976Abstract: Anti-CD40 antibodies are formulated as lyophilisate or liquid formulation. The lyophilisates can be reconstituted to give a solution with a high concentration of the antibody active ingredient for delivery to a patient without high levels of antibody aggregation. The lyophilisate can be reconstituted with an aqueous reconstituent to provide an aqueous composition in which the antibody has a concentration of at least 50 mg/ml. The lyophilisate or aqueous pharmaceutical composition may include one or more of a sugar, a buffering agent, a surfactant, and/or a free amino acid.Type: GrantFiled: September 26, 2018Date of Patent: March 17, 2020Assignee: Novartis AGInventors: Claudia Mueller, Matthias Willmann
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Publication number: 20190151450Abstract: Anti-CD40 antibodies are formulated as lyophilisate or liquid formulation. The lyophilisates can be reconstituted to give a solution with a high concentration of the antibody active ingredient for delivery to a patient without high levels of antibody aggregation. The lyophilisate can be reconstituted with an aqueous reconstituent to provide an aqueous composition in which the antibody has a concentration of at least 50 mg/ml. The lyophilisate or aqueous pharmaceutical composition may include one or more of a sugar, a buffering agent, a surfactant, and/or a free amino acid.Type: ApplicationFiled: September 26, 2018Publication date: May 23, 2019Applicant: Novartis AGInventors: Claudia MUELLER, Matthias WILLMANN
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Patent number: 10254085Abstract: A device for arranging an accessory on a firearm, in particular a handgun, is provided, wherein the device has a housing for receiving the accessory in the housing, wherein the housing can be fastened to the firearm, wherein the housing has a first portion with a front end wall and with a rear end wall at a distance from the front end wall, the housing has a second portion, which protrudes axially at the rear end wall of the first portion, the second portion has a fastening device for fastening the housing to the firearm, and the housing has a substantially L-shaped basic form. A firearm with a device for arranging an accessory on a firearm that is arranged on it or can be arranged on it is also provided.Type: GrantFiled: August 18, 2017Date of Patent: April 9, 2019Inventor: Matthias Willmann
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Patent number: 10111958Abstract: Anti-CD40 antibodies are formulated as lyophilizate or liquid formulation. The lyophilizates can be reconstituted to give a solution with a high concentration of the antibody active ingredient for delivery to a patient without high levels of antibody aggregation. The lyophilizate can be reconstituted with an aqueous reconstituent to provide an aqueous composition in which the antibody has a concentration of at least 50 mg/ml. The lyophilizate or aqueous pharmaceutical composition may include one or more of a sugar, a buffering agent, a surfactant, and/or a free amino acid.Type: GrantFiled: January 26, 2018Date of Patent: October 30, 2018Assignee: Novartis AGInventors: Claudia Mueller, Matthias Willmann
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Publication number: 20180169246Abstract: Anti-CD40 antibodies are formulated as lyophilisate or liquid formulation. The lyophilisates can be reconstituted to give a solution with a high concentration of the antibody active ingredient for delivery to a patient without high levels of antibody aggregation. The lyophilisate can be reconstituted with an aqueous reconstituent to provide an aqueous composition in which the antibody has a concentration of at least 50 mg/ml. The lyophilisate or aqueous pharmaceutical composition may include one or more of a sugar, a buffering agent, a surfactant, and/or a free amino acid.Type: ApplicationFiled: January 26, 2018Publication date: June 21, 2018Applicant: Novartis AGInventors: Claudia MUELLER, Matthias WILLMANN
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Publication number: 20170370679Abstract: A device for arranging an accessory on a firearm, in particular a handgun, is provided, wherein the device has a housing for receiving the accessory in the housing, wherein the housing can be fastened to the firearm, wherein the housing has a first portion with a front end wall and with a rear end wall at a distance from the front end wall, the housing has a second portion, which protrudes axially at the rear end wall of the first portion, the second portion has a fastening device for fastening the housing to the firearm, and the housing has a substantially L-shaped basic form. A firearm with a device for arranging an accessory on a firearm that is arranged on it or can be arranged on it is also provided.Type: ApplicationFiled: August 18, 2017Publication date: December 28, 2017Inventor: Matthias Willmann
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Publication number: 20150086559Abstract: Anti-CD40 antibodies are formulated as lyophilisate or liquid formulation. The lyophilisates can be reconstituted to give a solution with a high concentration of the antibody active ingredient for delivery to a patient without high levels of antibody aggregation. The lyophilisate can be reconstituted with an aqueous reconstituent to provide an aqueous composition in which the antibody has a concentration of at least 50 mg/ml. The lyophilisate or aqueous pharmaceutical composition may include one or more of a sugar, a buffering agent, a surfactant, and/or a free amino acid.Type: ApplicationFiled: May 2, 2013Publication date: March 26, 2015Applicant: NOVARTIS AGInventors: Claudia Mueller, Matthias Willmann
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Publication number: 20140004131Abstract: Anti-CD40 antibodies are formulated as lyophilisate or liquid formulation. The lyophilisates can be reconstituted to give a solution with a high concentration of the antibody active ingredient for delivery to a patient without high levels of antibody aggregation. The lyophilisate can be reconstituted with an aqueous reconstituent to provide an aqueous composition in which the antibody has a concentration of at least 50 mg/ml. The lyophilisate or aqueous pharmaceutical composition may include one or more of a sugar, a buffering agent, a surfactant, and/or a free amino acid.Type: ApplicationFiled: April 30, 2013Publication date: January 2, 2014Applicant: NOVARTIS AGInventors: Claudia Mueller, Matthias Willmann
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Patent number: 8618172Abstract: The present invention relates to a solid oral dosage form comprising a therapeutically effective amount of aliskiren or a pharmaceutically acceptable salt thereof, a therapeutically effective amount of HCTZ and a hydrophilic filler selected from the group a carbohydrate or combinations thereof, e.g. sugars, sugar alcohols and starches or combinations of these.Type: GrantFiled: June 21, 2007Date of Patent: December 31, 2013Assignee: Novartis AGInventor: Matthias Willmann
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Publication number: 20090203679Abstract: The present invention relates to a solid oral dosage form comprising a therapeutically effective amount of aliskiren or a pharmaceutically acceptable salt thereof, a therapeutically effective amount of HCTZ and a hydrophilic filler selected from the group a carbohydrate or combinations thereof, e.g. sugars, sugar alcohols and starches or combinations of these.Type: ApplicationFiled: June 21, 2007Publication date: August 13, 2009Inventor: Matthias Willmann