Abstract: The safety device includes a tubular body configured to receive a barrel, a head arrangement configured to abut against the flange and to lock into a flange, at least two actuation arms connecting the tubular body and the head arrangement, said actuation arms having a proximal link connected to the head arrangement by a proximal hinge and a distal link connected to the tubular body by a distal hinge. The proximal link and the distal link are connected by an intermediate hinge. The actuation arm is movable between a collapsed position in which the tubular body is maintained in a position proximally close to the flange uncovering the needle and an extended position in which the tubular body is maintained in a position distally distant from the head arrangement shielding the needle; a locking means for maintaining the actuation arms in a collapsed position and a locking means for maintaining the actuation arms in an extended position.

Abstract: Provided herein is a housing assembly for a drug delivery device, including a first housing part having a first proximal end comprising a first engagement portion and a second engagement portion, a first distal end, and a first sidewall therebetween defining a first longitudinal axis and a first interior, the first sidewall comprising one or more windows therethrough; and a second housing part having a second proximal end, a second distal end comprising a third engagement portion and a fourth engagement portion, and a second sidewall therebetween defining a second longitudinal axis and a second interior.

Abstract: A method for creating a sterile connection with a fluid in a container. The container has a sealing member sealing a first end of the container, and a barrier sealing a chamber in fluid communication with the sealing member. The method includes providing a valve sleeve assembly that includes a flexible sleeve having a barrier portion at an end of the flexible sleeve, a hollow first penetrator disposed within the flexible sleeve, and a hollow second penetrator at least partially disposed within the first penetrator. An interior of the flexible sleeve is sterile. The method also includes piercing the barrier portion and the barrier with the first penetrator, and displacing the second penetrator relative to the first penetrator and the sealing member to pierce the sealing member and establish the sterile connection with an interior of the container.

Abstract: A method for creating a sterile connection with a fluid in a container. The container has a sealing member sealing a first end of the container, and a barrier sealing a chamber in fluid communication with the sealing member. The method includes providing a valve sleeve assembly that includes a flexible sleeve having a barrier portion at an end of the flexible sleeve, a hollow first penetrator disposed within the flexible sleeve, and a hollow second penetrator at least partially disposed within the first penetrator. An interior of the flexible sleeve is sterile. The method also includes piercing the barrier portion and the barrier with the first penetrator, and displacing the second penetrator relative to the first penetrator and the sealing member to pierce the sealing member and establish the sterile connection with an interior of the container.