Patents by Inventor Matthieu Chodorge
Matthieu Chodorge has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20230235062Abstract: Human monoclonal antibodies directed against B7-H1 and uses of these antibodies in diagnostics and for the treatment of diseases associated with the activity and/or expression of B7-H1 are disclosed. Additionally, hybridomas or other cell lines expressing such antibodies are disclosed.Type: ApplicationFiled: November 1, 2022Publication date: July 27, 2023Inventors: CHRISTOPHE QUEVA, MICHELLE MORROW, SCOTT HAMMOND, MARAT ALIMZHANOV, JOHN BABCOOK, IAN FOLTZ, JASPAL SINGH KANG, LAURA SEKIROV, MELANIE BOYLE, MATTHIEU CHODORGE, ROSS A. STEWART, KATHLEEN ANN MULGREW
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Patent number: 11518809Abstract: Human monoclonal antibodies directed against B7-H1 and uses of these antibodies in diagnostics and for the treatment of diseases associated with the activity and/or expression of B7-H1 are disclosed. Additionally, hybridomas or other cell lines expressing such antibodies are disclosed.Type: GrantFiled: July 23, 2019Date of Patent: December 6, 2022Assignee: MEDIMMUNE LIMITEDInventors: Christophe Queva, Michelle Morrow, Scott Hammond, Marat Alimzhanov, John Babcock, Ian Foltz, Jaspal Singh Kang, Laura Sekirov, Melanie Boyle, Matthieu Chodorge, Ross A. Stewart, Kathleen Ann Mulgrew
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Publication number: 20210347900Abstract: This disclosure provides LOX1 (LOX1) binding proteins such as anti-LOX1 antibodies, and compositions and methods for making these binding proteins. In certain aspects the LOX1-binding proteins provided herein, inhibit, or antagonize LOX1 activity. In addition, the disclosure provides compositions and methods for diagnosing and treating conditions associated with atherosclerosis, thrombosis, coronary artery disease (CAD), ischemia (e.g., myocardial ischemia), infarction (e.g., myocardial infarction), acute coronary syndrome (ACS), stroke, reperfusion injury, restenosis, peripheral vascular disease, hypertension, heart failure, inflammation (e.g., chronic inflammation), angiogenesis, preeclampsia, cancer and other LOX1-mediated diseases and conditions.Type: ApplicationFiled: July 16, 2021Publication date: November 11, 2021Inventors: Andrew BUCHANAN, Matthieu CHODORGE, Peter CARIUK, Johanna HUSMARK, Clare BALENDRAN, Deepesh PANDEY, Fumin CHANG, Daniel E. BERKOWITZ, Lewis H. ROMER
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Patent number: 11078284Abstract: This disclosure provides LOX1 (LOX1) binding proteins such as anti-LOX1 antibodies, and compositions and methods for making these binding proteins. In certain aspects the LOX1-binding proteins provided herein, inhibit, or antagonize LOX1 activity. In addition, the disclosure provides compositions and methods for diagnosing and treating conditions associated with atherosclerosis, thrombosis, coronary artery disease (CAD), ischemia (e.g., myocardial ischemia), infarction (e.g., myocardial infarction), acute coronary syndrome (ACS), stroke, reperfusion injury, restenosis, peripheral vascular disease, hypertension, heart failure, inflammation (e.g., chronic inflammation), angiogenesis, preeclampsia, cancer and other LOX1-mediated diseases and conditions.Type: GrantFiled: November 2, 2018Date of Patent: August 3, 2021Assignee: MedImmune LimitedInventors: Andrew Buchanan, Matthieu Chodorge, Peter Cariuk, Johanna Husmark, Clare Balendran, Deepesh Pandey, Fumin Chang, Daniel E. Berkowitz, Lewis H. Romer
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Publication number: 20210017282Abstract: Human monoclonal antibodies directed against B7-H1 and uses of these antibodies in diagnostics and for the treatment of diseases associated with the activity and/or expression of B7-H1 are disclosed. Additionally, hybridomas or other cell lines expressing such antibodies are disclosed.Type: ApplicationFiled: July 23, 2019Publication date: January 21, 2021Inventors: CHRISTOPHE QUEVA, MICHELLE MORROW, SCOTT HAMMOND, MARAT ALIMZHANOV, JOHN BABCOCK, IAN FOLTZ, JASPAL SINGH KANG, LAURA SEKIROV, MELANIE BOYLE, MATTHIEU CHODORGE, ROSS A. STEWART, KATHLEEN ANN MULGREW
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Patent number: 10400039Abstract: Human monoclonal antibodies directed against B7-H1 and uses of these antibodies in diagnostics and for the treatment of diseases associated with the activity and/or expression of B7-H1 are disclosed. Additionally, hybridomas or other cell lines expressing such antibodies are disclosed.Type: GrantFiled: October 25, 2016Date of Patent: September 3, 2019Assignee: MEDIMMUNE LIMITEDInventors: Christophe Queva, Michelle Morrow, Scott Hammond, Marat Alimzhanov, John Babcock, Ian Nevin Foltz, Jaspal Singh Kang, Laura Sekirov, Melanie Boyle, Matthieu Chodorge, Ross A. Stewart, Kathleen Ann Mulgrew
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Publication number: 20190262368Abstract: This disclosure provides LOX1 (LOX1) binding proteins such as anti-LOX1 antibodies, and compositions and methods for making these binding proteins. In certain aspects the LOX1-binding proteins provided herein, inhibit, or antagonize LOX1 activity. In addition, the disclosure provides compositions and methods for diagnosing and treating conditions associated with atherosclerosis, thrombosis, coronary artery disease (CAD), ischemia (e.g., myocardial ischemia), infarction (e.g., myocardial infarction), acute coronary syndrome (ACS), stroke, reperfusion injury, restenosis, peripheral vascular disease, hypertension, heart failure, inflammation (e.g., chronic inflammation), angiogenesis, preeclampsia, cancer and other LOX1-mediated diseases and conditions.Type: ApplicationFiled: November 2, 2018Publication date: August 29, 2019Inventors: Andrew BUCHANAN, Matthieu CHODORGE, Peter CARIUK, Johanna HUSMARK, Clare BALENDRAN, Deepesh PANDEY, Fumin CHANG, Daniel E. BERKOWITZ, Lewis H. ROMER
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Publication number: 20190092877Abstract: This application provides anti-PCSK9˜GLP-1 fusions and methods for use.Type: ApplicationFiled: September 17, 2018Publication date: March 28, 2019Inventors: Anthony CELESTE, Matthieu CHODORGE, Andrew BUCHANAN, Cristina RONDINONE, Joseph GRIMSBY, Peter RAVN, Jonathan SEAMAN, David FAIRMAN
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Patent number: 10117889Abstract: This disclosure provides LOX1 (LOX1) binding proteins such as anti-LOX1 antibodies, and compositions and methods for making these binding proteins. In certain aspects the LOX1-binding proteins provided herein, inhibit, or antagonize LOX1 activity. In addition, the disclosure provides compositions and methods for diagnosing and treating conditions associated with atherosclerosis, thrombosis, coronary artery disease (CAD), ischemia (e.g., myocardial ischemia), infarction (e.g., myocardial infarction), acute coronary syndrome (ACS), stroke, reperfusion injury, restenosis, peripheral vascular disease, hypertension, heart failure, inflammation (e.g., chronic inflammation), angiogenesis, preeclampsia, cancer and other LOX1-mediated diseases and conditions.Type: GrantFiled: September 30, 2015Date of Patent: November 6, 2018Assignee: MedImmune LimitedInventors: Andrew Buchanan, Matthieu Chodorge, Peter Cariuk, Johanna Husmark, Clare Balendran, Deepesh Pandey, Fumin Chang, Daniel E. Berkowitz, Lewis H. Romer
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Patent number: 10077319Abstract: This application provides anti-PCSK9˜GLP-1 fusions and methods for use.Type: GrantFiled: February 20, 2015Date of Patent: September 18, 2018Assignees: MedImmune, LLC, MedImmune LimitedInventors: Anthony Celeste, Matthieu Chodorge, Andrew Buchanan, Cristina Rondinone, Joseph Grimsby, Peter Ravn, Jonathan Seaman, David Fairman
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Publication number: 20170304343Abstract: This disclosure provides LOX1 (LOX1) binding proteins such as anti-LOX1 antibodies, and compositions and methods for making these binding proteins. In certain aspects the LOX1-binding proteins provided herein, inhibit, or antagonize LOX1 activity. In addition, the disclosure provides compositions and methods for diagnosing and treating conditions associated with atherosclerosis, thrombosis, coronary artery disease (CAD), ischemia (e.g., myocardial ischemia), infarction (e.g., myocardial infarction), acute coronary syndrome (ACS), stroke, reperfusion injury, restenosis, peripheral vascular disease, hypertension, heart failure, inflammation (e.g., chronic inflammation), angiogenesis, preeclampsia, cancer and other LOX1-mediated diseases and conditions.Type: ApplicationFiled: September 30, 2015Publication date: October 26, 2017Inventors: Andrew BUCHANAN, Matthieu CHODORGE, Peter CARIUK, Johanna HUSMARK, Clare BALENDRAN, Deepesh PANDEY, Fumin CHANG, Daniel E. BERKOWITZ, Lewis H. ROMER
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Publication number: 20170137522Abstract: Human monoclonal antibodies directed against B7-H1 and uses of these antibodies in diagnostics and for the treatment of diseases associated with the activity and/or expression of B7-H1 are disclosed. Additionally, hybridomas or other cell lines expressing such antibodies are disclosed.Type: ApplicationFiled: October 25, 2016Publication date: May 18, 2017Applicant: MEDIMMUNE LIMITEDInventors: CHRISTOPHE QUEVA, MICHELLE MORROW, SCOTT HAMMOND, MARAT ALIMZHANOV, JOHN BABCOCK, IAN Nevin FOLTZ, JASPAL SINGH KANG, LAURA SEKIROV, MELANIE BOYLE, MATTHIEU CHODORGE, ROSS A. STEWARD, KATHLEEN ANN MULGREW
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Publication number: 20160369010Abstract: This application provides anti-PCSK9˜GLP-1 fusions and methods for use.Type: ApplicationFiled: February 20, 2015Publication date: December 22, 2016Inventors: Anthony Celeste, Matthieu CHODORGE, Andrew BUCHANAN, Cristina RONDINONE, Joseph GRIMSBY, Peter RAVN, Jonathan SEAMAN, David FAIRMAN
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Patent number: 9493565Abstract: Human monoclonal antibodies directed against B7-H1 and uses of these antibodies in diagnostics and for the treatment of diseases associated with the activity and/or expression of B7-H1 are disclosed. Additionally, hybridomas or other cell lines expressing such antibodies are disclosed.Type: GrantFiled: May 6, 2014Date of Patent: November 15, 2016Assignee: MedImmune LimitedInventors: Christophe Queva, Michelle Morrow, Scott Hammond, Marat Alimzhanov, John Babcock, Ian Nevin Foltz, Jaspal Singh Kang, Laura Sekirov, Melanie Boyle, Matthieu Chodorge, Ross A. Steward, Kathleen Ann Mulgrew
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Publication number: 20140356353Abstract: Human monoclonal antibodies directed against B7-H1 and uses of these antibodies in diagnostics and for the treatment of diseases associated with the activity and/or expression of B7-H1 are disclosed. Additionally, hybridomas or other cell lines expressing such antibodies are disclosed.Type: ApplicationFiled: May 6, 2014Publication date: December 4, 2014Inventors: CHRISTOPHE QUEVA, MICHELLE MORROW, SCOTT HAMMOND, MARAT ALIMZHANOV, JOHN BABCOCK, IAN Nevin FOLTZ, JASPAL SINGH KANG, LAURA SEKIROV, MELANIE BOYLE, MATTHIEU CHODORGE, ROSS A. STEWARD, KATHLEEN ANN MULGREW
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Patent number: 8779108Abstract: Human monoclonal antibodies directed against B7-H1 and uses of these antibodies in diagnostics and for the treatment of diseases associated with the activity and/or expression of B7-H1 are disclosed. Additionally, hybridomas or other cell lines expressing such antibodies are disclosed.Type: GrantFiled: November 24, 2010Date of Patent: July 15, 2014Assignee: MedImmune, LimitedInventors: Christophe Queva, Michelle Morrow, Scott Hammond, Marat Alimzhanov, John Babcook, Ian Nevin Foltz, Jaspal Singh Kang, Laura Sekirov, Melanie Boyle, Matthieu Chodorge, Ross A. Stewart, Kathleen Ann Mulgrew
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Publication number: 20130034559Abstract: Human monoclonal antibodies directed against B7-H1 and uses of these antibodies in diagnostics and for the treatment of diseases associated with the activity and/or expression of B7-H1 are disclosed.Type: ApplicationFiled: November 24, 2010Publication date: February 7, 2013Applicant: Medlmmune LimitedInventors: Christophe Queva, Michelle Morrow, Scott Hammond, Marat Alimzhanov, John Babcook, Ian Nevin Foltz, Jaspal Singh Kang, Laura Sekirov, Melanie Boyle, Matthieu Chodorge, Ross A. Stewart, Kathleen Ann Mulgrew
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Patent number: 7983849Abstract: The invention relates to methods of determining the mutational load of a gene bank obtained by random mutagenesis of a gene of interest by preparing a chart linking the mutational load of a gene bank obtained by random mutagenesis of a model gene with the fraction of mutated model genes observed in the bank; performing, in parallel, random mutagenesis of the model gene used for preparing the chart and the gene of interest to obtain the corresponding mutated gene banks; determining the mutational load of the gene bank obtained using the model gene on the basis of the chart plotted; and applying a correction factor to the mutational load of the mutated model gene bank to determine the mutational load in the gene bank of the mutated genes of interest.Type: GrantFiled: June 7, 2005Date of Patent: July 19, 2011Assignee: Proteus S.A.Inventors: Matthieu Chodorge, Laurent Fourage, Fabrice Lefevre, Jean-Michel Masson
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Publication number: 20080139397Abstract: The present invention relates to a method used to determine the mutational load of a gene bank obtained by means of random mutagenesis of a gene of interest comprising: a) the preparation of a chart linking the mutational load (ML) of gene bank obtained by means of random mutagenesis of a model gene with the fraction of mutated model genes observed in said bank; b) the random mutagenesis of the model gene used for the preparation of the chart for step (a) and the gene of interest to obtain the corresponding mutated gene banks; c) the determination of the mutational load (ML) of the gene bank obtained using the model gene in step (b) on the basis of the chart plotted in step (a); d) the application of a correction factor (CF) to the mutational load (ML) of the mutated model gene bank determined in step (c) to determine the mutational load (ML) of the banks of mutated genes of interest from step (b).Type: ApplicationFiled: June 7, 2005Publication date: June 12, 2008Applicant: Proteus S.A.Inventors: Matthieu Chodorge, Laurent Fourage, Fabrice Lefivre, Jean-Michel Masson