Patents by Inventor Matthieu Pierre Guibert

Matthieu Pierre Guibert has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • GENE THERAPY FOR NEURONAL CEROID LIPOFUSCINOSES
    Publication number: 20210393802
    Abstract: Provided herein are methods and compositions for treatment of Batten disease. Such compositions include a recombinant adeno-associated virus (rAAV), said rAAV comprising an AAV capsid, and a vector genome packaged therein, said vector genome comprising (a) an AAV 5? inverted terminal repeat (ITR) sequence; (b) a promoter; (c) a CLN2 coding sequence encoding a human TPP1; (d) an AAV 3? ITR. Also provided herein are methods of treating Batten disease comprising administering to a subject in need thereof the rAAV described herein via more than one route. Also provide herein are pharmaceutical compositions comprising the rAAV described herein and related methods of treating Batten disease.
    Type: Application
    Filed: November 13, 2019
    Publication date: December 23, 2021
    Inventors: Bhargavi Kondragunta, Subha Karumuthil Melethil, Matthieu Pierre Guibert, Andrew Christopher Mercer, Micheal James Carrell, Robert Thomas Stadelman, Franz Michael Gerner, Nicholas Alexander Piers Sascha Buss, Jared Bee, Tristan James Marshall, Roberto DePaz