Abstract: The invention relates to an electrode arrangement to be coupled to a high voltage source for a dielectric barrier discharge plasma treatment of a to be treated tissue of a patient, which treatment surface is used as a counter electrode, having a plasma generating to be coupled to the high voltage source via a first lead; a dielectric shielding the plasma generating from the surface to be treated; a spacer defining a structured surface on a side of said arrangement facing a surface to be treated, said plasma generating being fitted to the object to be treated and brought in contact with the dielectric, a driver circuit for driving the plasma generating coupled to said high voltage source, wherein the driver circuit drives the plasma generating in a first voltage; said driver arranged to simultaneously drive the plasma generating at a second voltage, wherein first and second voltages combined do not exceed a range of 3-8 k V.