Patents by Inventor Matti Vaismaa

Matti Vaismaa has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • CATECHOL O-METHYLTRANSFERASE ACTIVITY INHIBITING COMPOUNDS
    Publication number: 20220047540
    Abstract: Compounds of formula (I), wherein R1 is as defined in the claims, exhibit COMT enzyme inhibiting activity and are thus useful as COMT inhibitors. Methods of treatment and pharmaceutical dosage forms are also disclosed.
    Type: Application
    Filed: September 1, 2021
    Publication date: February 17, 2022
    Inventors: Marko AHLMARK, David DIN BELLE, Mika KAUPPALA, Anne LUIRO, Taina PAJUNEN, Jarmo PYSTYNEN, Eija TIAINEN, Matti VAISMAA, Josef MESSINGER
  • PYRAN DERVATIVES AS CYP11A1 (CYTOCHROME P450 MONOOXYGENASE 11A1) INHIBITORS
    Publication number: 20210347765
    Abstract: Compounds of formula (I) wherein R1, R2, R3, R4, R5, R23, R24, L, A and B are as defined in claim 1, or pharmaceutically acceptable salts thereof are disclosed. The compounds of formula (I) possess utility as cytochrome P450 monooxygenase 11A1 (CYP11A1) inhibitors. The compounds are useful as medicaments in the treatment of steroid receptor, particularly androgen receptor, dependent diseases and conditions, such as prostate cancer.
    Type: Application
    Filed: July 6, 2021
    Publication date: November 11, 2021
    Inventors: David DIN BELLE, Mikko Mäkelä, Mikko Passiniemi, Pekka Pietikäinen, Petteri Rummakko, Eija Tiainen, Matti Vaismaa, Gerd Wohlfahrt
  • Pyran dervatives as CYP11A1 (cytochrome P450 monooxygenase 11A1) inhibitors
    Patent number: 11098032
    Abstract: Compounds of formula (I) wherein R1, R2, R3, R4, R5, R23, R24, L, A and B are as defined in claim 1, or pharmaceutically acceptable salts thereof are disclosed. The compounds of formula (I) possess utility as cytochrome P450 monooxygenase 11A1 (CYP11A1) inhibitors. The compounds are useful as medicaments in the treatment of steroid receptor, particularly androgen receptor, dependent diseases and conditions, such as prostate cancer.
    Type: Grant
    Filed: June 8, 2020
    Date of Patent: August 24, 2021
    Assignee: ORION CORPORATION
    Inventors: David Din Belle, Mikko Mäkelä, Mikko Passiniemi, Pekka Pietikäinen, Petteri Rummakko, Eija Tiainen, Matti Vaismaa, Gerd Wohlfahrt
  • CATECHOL O-METHYLTRANSFERASE ACTIVITY INHIBITING COMPOUNDS
    Publication number: 20200352898
    Abstract: Compounds of formula (I), wherein R1 is as defined in the claims, exhibit COMT enzyme inhibiting activity and are thus useful as COMT inhibitors. Methods of treatment and pharmaceutical dosage forms are also disclosed.
    Type: Application
    Filed: June 5, 2020
    Publication date: November 12, 2020
    Inventors: Marko AHLMARK, David DIN BELLE, Mika KAUPPALA, Anne LUIRO, Taina PAJUNEN, Jarmo PYSTYNEN, Eija TIAINEN, Matti VAISMAA, Josef MESSINGER
  • PYRAN DERVATIVES AS CYP11A1 (CYTOCHROME P450 MONOOXYGENASE 11A1) INHIBITORS
    Publication number: 20200299280
    Abstract: Compounds of formula (I) wherein R1, R2, R3, R4, R5, R23, R24, L, A and B are as defined in claim 1, or pharmaceutically acceptable salts thereof are disclosed. The compounds of formula (I) possess utility as cytochrome P450 monooxygenase 11A1 (CYP11A1) inhibitors. The compounds are useful as medicaments in the treatment of steroid receptor, particularly androgen receptor, dependent diseases and conditions, such as prostate cancer.
    Type: Application
    Filed: June 8, 2020
    Publication date: September 24, 2020
    Inventors: David DIN BELLE, Mikko MÄKELÄ, Mikko PASSINIEMI, Pekka PIETIKÄINEN, Petteri RUMMAKKO, Eija TIAINEN, Matti VAISMAA, Gerd WOHLFAHRT
  • Pyran dervatives as CYP11A1 (cytochrome P450 monooxygenase 11A1) inhibitors
    Patent number: 10717726
    Abstract: Compounds of formula (I) wherein R1, R2, R3, R4, R5, R23, R24, L, A and B are as defined in claim 1, or pharmaceutically acceptable salts thereof are disclosed. The compounds of formula (I) possess utility as cytochrome P450 monooxygenase 11A1 (CYP11A1) inhibitors. The compounds are useful as medicaments in the treatment of steroid receptor, particularly androgen receptor, dependent diseases and conditions, such as prostate cancer.
    Type: Grant
    Filed: December 21, 2017
    Date of Patent: July 21, 2020
    Assignee: ORION CORPORATION
    Inventors: David Din Belle, Mikko Mäkelä, Mikko Passiniemi, Pekka Pietikäinen, Petteri Rummakko, Eija Tiainen, Matti Vaismaa, Gerd Wohlfahrt
  • CATECHOL O-METHYLTRANSFERASE ACTIVITY INHIBITING COMPOUNDS
    Publication number: 20200009103
    Abstract: Compounds of formula (I), wherein R1 is as defined in the claims, exhibit COMT enzyme inhibiting activity and are thus useful as COMT inhibitors. Methods of treatment and pharmaceutical dosage forms are also disclosed.
    Type: Application
    Filed: May 17, 2019
    Publication date: January 9, 2020
    Inventors: Marko AHLMARK, David DIN BELLE, Mika KAUPPALA, Anne LUIRO, Taina PAJUNEN, Jamo PYSTYNEN, Eija TIAINEN, Matti VAISMAA, Josef MESSINGER
  • PYRAN DERVATIVES AS CYP11A1 (CYTOCHROME P450 MONOOXYGENASE 11A1) INHIBITORS
    Publication number: 20190359601
    Abstract: Compounds of formula (I) wherein R1, R2, R3, R4, R5, R23, R24, L, A and B are as defined in claim 1, or pharmaceutically acceptable salts thereof are disclosed. The compounds of formula (I) possess utility as cytochrome P450 monooxygenase 11A1 (CYP11A1) inhibitors. The compounds are useful as medicaments in the treatment of steroid receptor, particularly androgen receptor, dependent diseases and conditions, such as prostate cancer.
    Type: Application
    Filed: December 21, 2017
    Publication date: November 28, 2019
    Inventors: David DIN BELLE, Mikko MÄKELÄ, Mikko PASSINIEMI, Pekka PIETIKÄINEN, Petteri RUMMAKKO, Eija TIAINEN, Matti VAISMAA, Gerd WOHLFAHRT
  • CATECHOL O-METHYLTRANSFERASE ACTIVITY INHIBITING COMPOUNDS
    Publication number: 20190029990
    Abstract: Compounds of formula (I), wherein R1 is as defined in the claims, exhibit COMT enzyme inhibiting activity and are thus useful as COMT inhibitors. Methods of treatment and pharmaceutical dosage forms are also disclosed.
    Type: Application
    Filed: July 30, 2018
    Publication date: January 31, 2019
    Inventors: Marko Ahlmark, David Din Belle, Mika Kauppala, Anne Luiro, Taina Pajunen, Jarmo Pystynen, Eija Tiainen, Matti Vaismaa, Josef Messinger
  • CATECHOL O-METHYLTRANSFERASE ACTIVITY INHIBITING COMPOUNDS
    Publication number: 20170165219
    Abstract: Compounds of formula (I), wherein R1 is as defined in the claims, exhibit COMT enzyme inhibiting activity and are thus useful as COMT inhibitors. Methods of treatment and pharmaceutical dosage forms are also disclosed.
    Type: Application
    Filed: August 2, 2016
    Publication date: June 15, 2017
    Inventors: Marko AHLMARK, David DIN BELLE, Mika KAUPPALA, Anne LUIRO, Taina PAJUNEN, Jarmo PYSTYNEN, Eija TIAINEN, Matti VAISMAA, Josef MESSINGER
  • Catechol O-methyltransferase activity inhibiting compounds
    Patent number: 9458128
    Abstract: Compounds of formula (I), wherein R1 is as defined in the claims, exhibit COMT enzyme inhibiting activity and are thus useful as COMT inhibitors. Methods of treatment and pharmaceutical dosage forms are also disclosed.
    Type: Grant
    Filed: May 23, 2013
    Date of Patent: October 4, 2016
    Assignee: ORION CORPORATION
    Inventors: Marko Ahlmark, David Din Belle, Mika Kauppala, Anne Luiro, Taina Pajunen, Jarmo Pystynen, Eija Tiainen, Matti Vaismaa, Josef Messinger
  • CATECHOL O-METHYLTRANSFERASE ACTIVITY INHIBITING COMPOUNDS
    Publication number: 20150218124
    Abstract: Compounds of formula (I), wherein R1 is as defined in the claims, exhibit COMT enzyme inhibiting activity and are thus useful as COMT inhibitors. Methods of treatment and pharmaceutical dosage forms are also disclosed.
    Type: Application
    Filed: May 23, 2013
    Publication date: August 6, 2015
    Inventors: Marko Ahlmark, David Din Belle, Mika Kauppala, Anne Luiro, Taina Pajunen, Jarmo Pystynen, Eija Tianen, Matti Vaismaa, Josef Messinger