Abstract: A peritoneal dialysis system includes a housing; a dialysis fluid pump housed by the housing; a patient line extendable from the housing; and a hose reel located within the housing, the hose reel configured to coil the patient line when disconnected from a patient. The patient line may be a dual lumen patient line, wherein the dual lumen patient line is coiled about the hose reel during a disinfection sequence for disinfecting the dual lumen patient line and the dialysis fluid pump.

Abstract: A peritoneal dialysis (“PD”) system includes a dialysis fluid pump having a reusable pump body that accepts PD fluid for pumping; a dialysis fluid inline heater including a reusable heater body that accepts PD fluid for heating; a patient line connector; a drain line connector; a first reusable PD fluid line including a first connector configured to mate with the patient line connector; a second reusable PD fluid line including a second connector configured to mate with the drain line connector; and a control unit configured to run a heat cleaning (e.g., heat disinfection or heat sterilization) sequence after PD treatment, wherein the first connector of the first reusable PD fluid line is mated with the patient line connector, the second connector of the second reusable PD fluid line is mated with the drain line connector, and the dialysis fluid pump and perhaps the dialysis fluid inline heater are actuated.

Abstract: An optical detection apparatus is arranged to detect particles in a fluid flowing through a tubing portion of transparent or translucent material. The apparatus comprises a holder for the tubing portion; a light emitting device configured to irradiate a target volume inside the tubing portion when arranged in the holder; and at least one light receiving device configured to receive light from the target volume when irradiated by the light emitting device and generate one or more time-dependent output signals indicative of the received light. A computation device is configured to determine a parameter indicative of temporal variability in the one or more time-dependent output signals and estimate the density based on the parameter, which has been found to be robust to structural differences between tubings and allows the apparatus to be deployed without calibration.

Abstract: A blood treatment apparatus is disclosed. The example apparatus includes a blood treatment unit including a fluid inlet and a fluid outlet and a blood line. The apparatus also includes a fluid line including an upstream fluid line configured to receive electrically conductive treatment fluid from a fluid source and pass the electrically conductive treatment fluid to the fluid inlet of the blood treatment unit and a downstream fluid line connected to the fluid outlet of the blood treatment unit for delivering the used electrically conductive treatment fluid to a fluid sink. The apparatus further includes a flow divider arranged in the downstream fluid line and configured to separate the used electrically conductive treatment fluid in the downstream fluid line into to a first fluid section and a second fluid section, thereby electrically isolating the first and second fluid sections.

Abstract: A peritoneal dialysis system includes a control unit configured to (i) store a sleep state pattern for the patient, (ii) begin a patient drain followed by a patient fill when at least one sensor indicates that the patient is in a deep sleep state, (iii) extend a dwell period if the sleep state pattern indicates that the patient will enter a subsequent deep sleep state within a first time duration after a programmed dwell period, and (iv) shorten the dwell period if the sleep state pattern indicates that the patient will leave the deep sleep state within a second time duration after an end of the programmed dwell period. The system alternatively or additionally assesses or records a stress level of and/or a fluid/caloric intake by the patient and takes actions accordingly.

Abstract: A peritoneal dialysis (“PD”) system includes a housing; a dialysis fluid pump housed by the housing; a dual lumen patient line extending from the housing; a filter set including a final stage filter located along a first line, and which includes a second line in parallel with the first line, the first line in fluid communication with a first lumen of the dual lumen patient line, and the second line in fluid communication with a second lumen of the dual lumen patient line; a pressure sensor located within the housing and positioned so as to sense a static or substantially static PD fluid pressure in the second lumen while fresh PD fluid is pumped through the first lumen and the final stage filter; and a control unit configured to use the sensed static or substantially static pressure in a pressure control routine for the dialysis fluid pump.

Abstract: A peritoneal dialysis (“PD”) system includes a housing; a dialysis fluid pump housed by the housing and including a reusable pump body that accepts PD fluid for pumping; a dialysis fluid inline heater housed by the housing and including a reusable heater body that accepts PD fluid for heating; at least one reusable PD fluid line extending from the housing; at least one disinfection connector supported by the housing and configured to accept one of the at least one reusable PD fluid line; and a control unit configured to run a disinfection sequence after a PD treatment, wherein each of the at least one reusable PD fluid line is connected to one of the at least one disinfection connectors, and wherein at least one of the dialysis fluid pump or the dialysis fluid inline heater is actuated by the control unit during the disinfection sequence.

Abstract: A blood treatment apparatus is disclosed. The example apparatus includes a blood treatment unit including a fluid inlet and a fluid outlet and a blood line. The apparatus also includes a fluid line including an upstream fluid line configured to receive electrically conductive treatment fluid from a fluid source and pass the electrically conductive treatment fluid to the fluid inlet of the blood treatment unit and a downstream fluid line connected to the fluid outlet of the blood treatment unit for delivering the used electrically conductive treatment fluid to a fluid sink. The apparatus further includes a flow divider arranged in the downstream fluid line and configured to separate the used electrically conductive treatment fluid in the downstream fluid line into to a first fluid section and a second fluid section, thereby electrically isolating the first and second fluid sections.

Abstract: A blood treatment apparatus is disclosed. In an example, the blood treatment apparatus includes a blood treatment unit; a blood line configured to extract blood from a blood source, pass the blood through the blood treatment unit and deliver treated blood to a target vessel; and a fluid line configured to pass treatment fluid through the blood treatment unit and deliver used treatment fluid to a fluid sink. A flow divider is arranged in the fluid line for separating treatment fluid into to a first fluid section and a second fluid section, thereby electrically isolating the fluid sections such that electrical current flowing in the fluid line between the fluid sections is limited. Related manufacturing and verification methods are also described.

Abstract: A monitoring device operates on a pressure signal from a blood processing apparatus which has an extracorporeal blood circuit for pumping blood through a dialyzer, and a treatment fluid supply system for pumping a treatment fluid through the dialyzer. The monitoring device has a first input block for obtaining a first pressure signal, and a second input block for obtaining a second pressure signal. An emulation block generates, as a function of the second pressure signal, an emulated first pressure signal which emulates a concurrent signal response of the first pressure sensor, and a filtering block generates a filtered signal as a function of the first pressure signal and the emulated first pressure signal, so as to suppress, in the filtered signal compared to the first pressure signal, signal interferences originating from the treatment fluid supply system. A pulse detection block processes the filtered signal for detection of subject pulses.

Abstract: A blood treatment apparatus comprising: a blood treatment unit; a blood line configured to extract blood from a blood source, pass the blood through the blood treatment unit and deliver treated blood to a target vessel; and a fluid line configured pass treatment fluid through the blood treatment unit and deliver used treatment fluid to a fluid sink. A flow divider is arranged in the fluid line separates treatment fluid into to a first fluid section and a second fluid section, thereby electrically isolating the fluid sections such that electrical current flowing in the fluid line between the fluid sections is limited. Related manufacturing and verification methods are also described.

Abstract: A blood treatment apparatus comprising: a blood treatment unit; a blood line configured to extract blood from a blood source, pass the blood through the blood treatment unit and deliver treated blood to a target vessel; and a fluid line configured to pass treatment fluid through the blood treatment unit and deliver used treatment fluid to a fluid sink. A flow divider is arranged in the fluid line that separates treatment fluid into a first fluid section and a second fluid section, thereby electrically isolating the fluid sections such that electrical current flowing in the fluid line between the fluid sections is limited. Related manufacturing and verification methods are also described.

Abstract: A filtering device receives a signal from a pressure sensor in an extracorporeal fluid circuit connected to a subject and processes the signal to separate physiological pulses, e.g. from the subject's heart, from interference pulses, e.g. from a pump in the fluid circuit. The device repeatedly (iteratively) processes a signal segment by alternately subtracting (S3) a template signal from the signal segment, and applying a refinement processing (S6) to the resulting difference signal to generate a new template signal. By proper selection (S2) of the initial template signal, consecutive difference signals will alternately approximate the sequence of interference pulses in the signal segment and the sequence of physiological pulses in the signal segment. The refinement processing (S6) aims at alternately cleaning up unwanted residuals from interference pulses and physiological pulses, respectively, in the respective difference signal, so as to improve the accuracy of the template signal between the subtractions.

Abstract: A monitoring device operates on a pressure signal from a blood processing apparatus which has an extracorporeal blood circuit for pumping blood through a dialyzer, and a treatment fluid supply system for pumping a treatment fluid through the dialyzer. The monitoring device has a first input block for obtaining a first pressure signal, and a second input block for obtaining a second pressure signal. An emulation block generates, as a function of the second pressure signal, an emulated first pressure signal which emulates a concurrent signal response of the first pressure sensor, and a filtering block generates a filtered signal as a function of the first pressure signal and the emulated first pressure signal, so as to suppress, in the filtered signal compared to the first pressure signal, signal interferences originating from the treatment fluid supply system. A pulse detection block processes the filtered signal for detection of subject pulses.

Abstract: A monitoring device (7) operates on a pressure signal from a blood processing apparatus, e.g. a dialysis machine, which has an extracorporeal blood circuit connected to a vascular system of a subject for pumping blood through a dialyzer, and a treatment fluid supply system for pumping a treatment fluid through the dialyzer. The monitoring device (7) has a first input block (50) for obtaining a first pressure signal (y) from a first pressure sensor (6a) in the extracorporeal blood circuit, and a second input block (51) for obtaining a second pressure signal (w) from a second pressure sensor (6b) in the treatment fluid supply system.

Abstract: A blood treatment apparatus adapted to preserve a blood treatment unit between blood treatment sessions. The blood treatment apparatus is configured to i) perform a blood treatment session and thereby use the blood treatment unit, ii) fill the blood treatment unit with a preservation fluid comprising at least one treatment fluid concentrate of a type that is used to prepare the treatment fluid, iii) maintain the preservation fluid in the blood treatment unit until a next blood treatment session is prepared, iv) dispatch the preservation fluid from the blood treatment unit in preparation of a next blood treatment session, and v) perform a next blood treatment session and thereby extend the use of the blood treatment unit. A related method is also described.

Abstract: A device removes first pulses in a pressure signal of a pressure sensor which is arranged in a fluid containing system to detect the first pulses, which originate from a first pulse generator, and second pulses, which originate from a second pulse generator. The first pulse generator operates in a sequence of pulse cycles, each pulse cycle resulting in at least one first pulse. The device repetitively obtains a current data sample, calculates a corresponding reference value and subtracts the reference value from the current data sample. The reference value is calculated as a function of other data sample(s) in the same pressure signal. The fluid containing system may include an extracorporeal blood flow circuit, e.g. as part of a dialysis machine, and a cardiovascular system of a human patient.

Abstract: A disposable for use in blood treatment including a blood treatment unit and two membrane pumps connected in parallel on one side of the blood treatment unit. The disposable is operable in a single-needle mode, in which the pumps generate a pulsatile flow of blood through the blood treatment unit, and in a double-needle mode, in which the pumps generate an essentially continuous flow of blood through the blood treatment unit. The pumps connect to a supply of treatment fluid such that alternating flows of treatment fluid causes the pumps to generate the desired flows of blood in the single-needle and double-needle modes. The treatment fluid may be used as motive fluid for displacing the blood in the membrane pumps and/or as control fluid for controlling opening and/or closing of upstream and downstream commutation valves in the membrane pumps.

Abstract: A washer press apparatus for washing and dewatering a wide range of solids concentrations of pulp in liquid suspensions includes multiple distinct displacement wash zones about a drum with multiple nips.

Abstract: A device monitors a blood path from a blood vessel access of a human subject through an extracorporeal blood processing apparatus and back to the blood vessel access. A pumping device in the blood path is operable to pump blood through the blood path from the blood withdrawal device to the blood return device. The monitoring device obtains pressure data from a pressure sensor arranged upstream of the pumping device in the blood path, and processes the pressure data for detection of a disruption of the blood path downstream of the pumping device, e.g. caused by VND (Venous Needle Dislodgement).