Patents by Inventor Maud Urbanski

Maud Urbanski has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • HETEROARYL LINKED QUINOLINYL MODULATORS OF RORgammat
    Publication number: 20150105365
    Abstract: The present invention comprises compounds of Formula I. wherein: R1, R2, R3, R4, R5, R6, R7 R8, and R9 are defined in the specification. The invention also comprises a method of treating or ameliorating a syndrome, disorder or disease, wherein said syndrome, disorder or disease is rheumatoid arthritis or psoriasis. The invention also comprises a method of modulating ROR?t activity in a mammal by administration of a therapeutically effective amount of at least one compound of claim 1.
    Type: Application
    Filed: October 15, 2013
    Publication date: April 16, 2015
    Applicant: Janssen Pharmaceutica NV
    Inventors: Kristi A. Leonard, Kent Barbay, James P. Edwards, Kevin D. Kreutter, David A. Kummer, Umar Maharoof, Rachel Nishimura, Maud Urbanski, Hariharan Venkatesan, Aihua Wang, Ronald L. Wolin, Craig R. Woods, Anne Fourie, Xiaohua Xue, Maxwell D. Cummings
  • PHENYL LINKED QUINOLINYL MODULATORS OF RORyt
    Publication number: 20150105404
    Abstract: The present invention comprises compounds of Formula I. wherein: R1, R2, R3, R4, R5, R6, R7, R8, and R9 are defined in the specification. The invention also comprises a method of treating or ameliorating a syndrome, disorder or disease, wherein said syndrome, disorder or disease is rheumatoid arthritis or psoriasis. The invention also comprises a method of modulating ROR?t activity in a mammal by administration of a therapeutically effective amount of at least one compound of claim 1.
    Type: Application
    Filed: October 15, 2013
    Publication date: April 16, 2015
    Applicant: Janssen Pharmaceutica NV
    Inventors: Kristi A. Leonard, Kent Barbay, James P. Edwards, Kevin D. Kreutter, David A. Kummer, Umar Maharoof, Rachel Nishimura, Maud Urbanski, Hariharan Venkatesan, Aihua Wang, Ronald L. Wolin, Craig R. Woods, Anne Fourie, Xiaohua Xue, Maxwell D. Cummings
  • METHYLENE LINKED QUINOLINYL MODULATORS OF RORyt
    Publication number: 20150105366
    Abstract: The present invention comprises compounds of Formula I. wherein: R1, R2, R3, R4, R5, R6, R7, R8, and R9 are defined in the specification. The invention also comprises a method of treating or ameliorating a syndrome, disorder or disease, wherein said syndrome, disorder or disease is rheumatoid arthritis or psoriasis. The invention also comprises a method of modulating ROR?t activity in a mammal by administration of a therapeutically effective amount of at least one compound of claim 1.
    Type: Application
    Filed: October 15, 2013
    Publication date: April 16, 2015
    Applicant: Janssen Pharmaceutica NV
    Inventors: Kristi A. Leonard, Kent Barbay, James P. Edwards, Kevin D. Kreutter, David A. Kummer, Umar Maharoof, Rachel Nishimura, Maud Urbanski, Hariharan Venkatesan, Aihua Wang, Ronald L. Wolin, Craig R. Woods, Anne Fourie, Xiaohua Xue, Maxwell D. Cummings, William Moore Jones, Steven Goldberg
  • ALKYL LINKED QUINOLINYL MODULATORS OF RORyt
    Publication number: 20150105369
    Abstract: The present invention comprises compounds of Formula I. wherein: R1, R2, R3, R4, R5, R6, R7, R8, and R9 are defined in the specification. The invention also comprises a method of treating or ameliorating a syndrome, disorder or disease, wherein said syndrome, disorder or disease is rheumatoid arthritis or psoriasis. The invention also comprises a method of modulating ROR?t activity in a mammal by administration of a therapeutically effective amount of at least one compound of claim 1.
    Type: Application
    Filed: October 14, 2014
    Publication date: April 16, 2015
    Inventors: KRISTI A. LEONARD, KENT BARBAY, JAMES P. EDWARDS, KEVIN D. KREUTTER, DAVID A. KUMMER, UMAR MAHAROOF, RACHEL NISHIMURA, MAUD URBANSKI, HARIHARAN VENKATESAN, AIHUA WANG, RONALD L. WOLIN, CRAIG R. WOODS, ANNE FOURIE, XIAOHUA XUE, MAXWELL D. CUMMINGS
  • Substituted dihydroisoindolones as allosteric modulators of glucokinase
    Patent number: 8796313
    Abstract: The present invention relates to compounds of Formula (I), methods for preparing these compounds, compositions, intermediates and derivatives thereof and for treating glucokinase mediated disorders. More particularly, the compounds of the present invention are glucokinase modulators useful for treating disorders including, but not limited to, type II diabetes.
    Type: Grant
    Filed: October 30, 2006
    Date of Patent: August 5, 2014
    Assignee: Janssen Pharmaceutica N.V.
    Inventors: Joseph Dudash, Philip Rybczynski, Maud Urbanski, Amy Xiang, Roxanne Zeck, Xiaoyan Zhang, Yongzheng Zhang
  • HETEROARYL LINKED QUINOLINYL MODULATORS OF RORyt
    Publication number: 20140107096
    Abstract: The present invention comprises compounds of Formula I. wherein: R1, R2, R3, R4, R5, R6, R7, R8, and R9 are defined in the specification. The invention also comprises a method of treating or ameliorating a syndrome, disorder or disease, wherein said syndrome, disorder or disease is rheumatoid arthritis or psoriasis. The invention also comprises a method of modulating ROR?t activity in a mammal by administration of a therapeutically effective amount of at least one compound of claim 1.
    Type: Application
    Filed: October 15, 2013
    Publication date: April 17, 2014
    Applicant: JANSSEN PHARMACEUTICA NV
    Inventors: KRISTI A. LEONARD, KENT BARBAY, JAMES P. EDWARDS, KEVIN D. KREUTTER, DAVID A. KUMMER, UMAR MAHAROOF, RACHEL NISHIMURA, MAUD URBANSKI, HARIHARAN VENKATESAN, AIHUA WANG, RONALD L. WOLIN, CRAIG R. WOODS, ANNE FOURIE, XIAOHUA XUE
  • HETEROARYL LINKED QUINOLINYL MODULATORS OF RORyt
    Publication number: 20140107097
    Abstract: The present invention comprises compounds of Formula I. wherein: R1, R2, R3, R4, R5, R6, R7, R8, and R9 are defined in the specification. The invention also comprises a method of treating or ameliorating a syndrome, disorder or disease, wherein said syndrome, disorder or disease is rheumatoid arthritis or psoriasis. The invention also comprises a method of modulating ROR?t activity in a mammal by administration of a therapeutically effective amount of at least one compound of claim 1.
    Type: Application
    Filed: October 15, 2013
    Publication date: April 17, 2014
    Applicant: Janssen Pharmaceutica NV
    Inventors: Kristi A. Leonard, Kent Barbay, James P. Edwards, Kevin D. Kreutter, David A. Kummer, Umar Maharoof, Rachel Nishimura, Maud Urbanski, Hariharan Venkatesan, Aihua Wang, Ronald L. Wolin, Craig R. Woods, Anne Fourie, Xiaohua Xue, Taraneh Mirzadegan, Kelly Ganamet
  • METHYLENE LINKED QUINOLINYL MODULATORS OF RORyt
    Publication number: 20140107094
    Abstract: The present invention comprises compounds of Formula I. wherein: R1, R2, R3, R4, R5, R6, R7, R8, and R9 are defined in the specification. The invention also comprises a method of treating or ameliorating a syndrome, disorder or disease, wherein said syndrome, disorder or disease is rheumatoid arthritis or psoriasis. The invention also comprises a method of modulating ROR?t activity in a mammal by administration of a therapeutically effective amount of at least one compound of claim 1.
    Type: Application
    Filed: October 15, 2013
    Publication date: April 17, 2014
    Applicant: Janssen Pharmaceutica NV
    Inventors: Kristi A. Leonard, Kent Barbay, James P. Edwards, Kevin D. Kreutter, David A. Kummer, Umar Maharoof, Rachel Nishimura, Maud Urbanski, Hariharan Venkatesan, Aihua Wang, Ronald L. Wolin, Craig R. Woods, Joan Pierce, Steven Goldberg, Anne Fourie, Xiaohua Xue
  • Substituted pyrrolones as allosteric modulators of glucokinase
    Patent number: 8680122
    Abstract: The present invention relates to compounds of Formula (I), methods for preparing these compounds, compositions, intermediates and derivatives thereof and for treating glucokinase mediated disorders. More particularly, the compounds of the present invention are glucokinase modulators useful for treating disorders including, but not limited to, type II diabetes.
    Type: Grant
    Filed: October 30, 2006
    Date of Patent: March 25, 2014
    Assignee: Janssen Pharmacetica N.V.
    Inventors: Maud Urbanski, Amy Xiang, Roxanne Zeck
  • Dihydroisoindolones as allosteric modulators of glucokinase
    Patent number: 7928246
    Abstract: The present invention relates to compounds of Formula (I), methods for preparing these compounds, compositions, intermediates and derivatives thereof and for treating glucokinase mediated disorders. More particularly, the compounds of the present invention are glucokinase modulators useful for treating disorders including, but not limited to, type II diabetes.
    Type: Grant
    Filed: April 15, 2009
    Date of Patent: April 19, 2011
    Assignee: Janssen Pharmaceutica NV
    Inventors: Hiayan Bian, Joseph Dudash, Mona Patel, Philip Rybczynski, Yongzheng Zhang, Mary Pat Beavers, Maud Urbanski, Min (Amy) Xiang, Roxanne Zeck
  • Substituted indole-O-glucosides
    Patent number: 7820630
    Abstract: Substituted indole-O-glucosides, compositions containing them, and methods of using them, for example for the treatment of diabetes and Syndrome X are disclosed.
    Type: Grant
    Filed: September 22, 2009
    Date of Patent: October 26, 2010
    Assignee: Janssen Pharmaceutica NV
    Inventors: Mary Pat Beavers, Mona Patel, Philip Rybczynski, Maud Urbanski, Xiaoyan Zhang
  • Substituted fused heterocyclic C-glycosides
    Patent number: 7816328
    Abstract: This invention relates to substituted fused heterocyclic C-glycosides, compositions containing them, and methods of using them, for example, for the treatment or prophylaxis of diabetes and Syndrome X.
    Type: Grant
    Filed: September 11, 2009
    Date of Patent: October 19, 2010
    Assignee: Janssen Pharmaceutica NV
    Inventors: Philip Rybczynski, Maud Urbanski, Xiaoyan Zhang
  • Substituted indazole-O-glucosides
    Patent number: 7816331
    Abstract: Substituted indazole-O-glucosides, compositions containing them, and methods of using them, for example for the treatment of diabetes and Syndrome X are disclosed.
    Type: Grant
    Filed: September 22, 2009
    Date of Patent: October 19, 2010
    Assignee: Janssen Pharmaceutica NV
    Inventors: Mona Patel, Philip J. Rybczynski, Maud Urbanski, Xiaoyan Zhang
  • Substituted benzimidazole-, benztriazole-, and benzimidazolone-O-glucosides
    Patent number: 7816330
    Abstract: This invention relates to substituted benzimidazole-O-glucosides, benztriazole-O-glucosides, and benzimidazolone-O-glucosides, compositions containing them, and methods of using them, for example, for the treatment or prophylaxis of diabetes and Syndrome X.
    Type: Grant
    Filed: September 11, 2009
    Date of Patent: October 19, 2010
    Assignee: Janssen Pharmaceutica NV
    Inventor: Maud Urbanski
  • SUBSTITUTED INDAZOLE-O-GLUCOSIDES
    Publication number: 20100062971
    Abstract: Substituted indazole-O-glucosides, compositions containing them, and methods of using them, for example for the treatment of diabetes and Syndrome X are disclosed.
    Type: Application
    Filed: September 22, 2009
    Publication date: March 11, 2010
    Inventors: Mona Patel, Philip J. Rybczynski, Maud Urbanski, Xiaoyan Zhang
  • SUBSTITUTED INDOLE-O-GLUCOSIDES
    Publication number: 20100009900
    Abstract: Substituted indole-O-glucosides, compositions containing them, and methods of using them, for example for the treatment of diabetes and Syndrome X are disclosed.
    Type: Application
    Filed: September 22, 2009
    Publication date: January 14, 2010
    Inventors: Mary Pat Beavers, Mona Patel, Philip Rybczynski, Maud Urbanski, Xiaoyan Zhang
  • SUBSTITUTED BENZIMIDAZOLE-, BENZTRIAZOLE-, AND BENZIMIDAZOLONE-O-GLUCOSIDES
    Publication number: 20100004188
    Abstract: This invention relates to to substituted benzimidazole-O-glucosides, benztriazole-O-glucosides, and benzimidazolone-O-glucosides, compositions containing them, and methods of using them, for example, for the treatment or prophylaxis of diabetes and Syndrome X.
    Type: Application
    Filed: September 11, 2009
    Publication date: January 7, 2010
    Inventor: Maud Urbanski
  • SUBSTITUTED FUSED HETEROCYCLIC C-GLYCOSIDES
    Publication number: 20100004160
    Abstract: This invention relates to substituted fused heterocyclic C-glycosides, compositions containing them, and methods of using them, for example, for the treatment or prophylaxis of diabetes and Syndrome X.
    Type: Application
    Filed: September 11, 2009
    Publication date: January 7, 2010
    Inventors: Philip Rybczynski, Maud Urbanski, Xiaoyan Zhang
  • DIHYDROISOINDOLONES AS ALLOSTERIC MODULATORS OF GLUCOKINASE
    Publication number: 20090202525
    Abstract: The present invention relates to compounds of Formula (1), methods for preparing these compounds, compositions, intermediates and derivatives thereof and for treating glucokinase mediated disorders. More particularly, the compounds of the present invention are glucokinase modulators useful for treating disorders including, but not limited to, type II diabetes.
    Type: Application
    Filed: April 15, 2009
    Publication date: August 13, 2009
    Inventors: Haiyan Bian, Joseph Dudash, Mona Patel, Philip Rybczynski, Yongzheng Zhang, Mary Pat Beavers, Maud Urbanski, Min (Amy) Xiang, Roxanne Zeck
  • SUBSTITUTED INDOLE-O-GLUCOSIDES
    Publication number: 20090105164
    Abstract: Substituted indole-O-glucosides, compositions containing them, and methods of using them, for example for the treatment of diabetes and Syndrome X are disclosed.
    Type: Application
    Filed: December 18, 2008
    Publication date: April 23, 2009
    Inventors: Mary Pat Beavers, Mona Patel, Philip Rybczynski, Maud Urbanski, Xiaoyan Zhang