Patents by Inventor Maureen Bourner

Maureen Bourner has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • CELLS HAVING DISRUPTED EXPRESSION OF PROTEINS INVOLVED IN ADME AND TOXICOLOGY PROCESSES
    Publication number: 20160266093
    Abstract: The present invention provides cells comprising disrupted expression of at least one membrane transporter, drug metabolizing enzyme, xenobiotic sensor, or cellular stress response pathway protein. Also provided are methods for assessing the effect of an agent in the cells disclosed herein relative to comparable control cells.
    Type: Application
    Filed: January 15, 2016
    Publication date: September 15, 2016
    Inventors: Maureen Bourner, Timothy Brayman, Gary Davis, Michael D. Mitchell, David C. Thompson, Yongling Xiao
  • CELLS HAVING DISRUPTED EXPRESSION OF PROTEINS INVOLVED IN ADME AND TOXICOLOGY PROCESSES
    Publication number: 20130316391
    Abstract: The present invention provides cells comprising disrupted expression of at least one membrane transporter, drug metabolizing enzyme, xenobiotic sensor, or cellular stress response pathway protein. Also provided are methods for assessing the effect of an agent in the cells disclosed herein relative to comparable control cells.
    Type: Application
    Filed: December 28, 2011
    Publication date: November 28, 2013
    Applicant: Sigmaaldrich Co., LLC
    Inventors: Maureen Bourner, Timothy Brayman, Gary Davis, Michael D. Mitchell, David C. Thompson, Yongling Xiao
  • P-cadherin antibodies
    Publication number: 20060240001
    Abstract: The present invention relates to antibodies including human antibodies and antigen-binding portions thereof that bind to P-cadherin, and that function to inhibit P-cadherin. The invention also relates to heavy and light chain immunoglobulins derived from human P-cadherin antibodies and nucleic acid molecules encoding such immunoglobulins. The present invention also relates to methods of making human P-cadherin antibodies, compositions comprising these antibodies and methods of using the antibodies and compositions. The invention also relates to transgenic animals or plants comprising nucleic acid molecules of the present invention.
    Type: Application
    Filed: April 25, 2006
    Publication date: October 26, 2006
    Inventors: Christopher Bauer, Maureen Bourner, Melanie Boyle, Gerald Casperson, David Griggs, Richard Head, William Joy, Richard Mazzarella, Ralph Minter, Mark Moffat, Barrett Thiele, Todd Vanarsdale
  • Differentially expressed genes involved in cancer, the polypeptides encoded thereby, and methods of using the same
    Publication number: 20050037439
    Abstract: The invention relates nucleic acids and their encoded polypeptides, whose expression is modulated in cancer or tumor cells. The invention further relates to methods useful for treating or modulating cancer or tumors in mammals in need of such biological effect. This includes the diagnosis and treatment of oncological disorders. Additionally, the present invention further relates to the use of antibodies against the polypeptides of the present invention as diagnostic probes or as therapeutic agents as well as the use of polynucleotide sequences encoding the polypeptides of the present invention as diagnostic probes or therapeutic agents for the treatment of a broad range of pathological states.
    Type: Application
    Filed: October 29, 2003
    Publication date: February 17, 2005
    Inventors: Maureen Bourner, Paul Hippenmeyer, Richard Head, Richard Mazzarella, Nicholas Staten, Barbara Klein