Patents by Inventor Maureen Joan Young

Maureen Joan Young has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for reducing the 6-keto group of a morphinan alkaloid to the 6-hydroxy group by hydrogenation
    Patent number: 8853402
    Abstract: A process for the reduction of a 6-keto group in a morphinan alkaloid to the corresponding 6-hydroxy group includes hydrogenating the 6-keto group using gaseous hydrogen in the presence of a heterogeneous catalyst and a solvent, to yield the 6-hydroxy morphinan alkaloid, wherein the reduction is carried out at a pH in the range of about 5 to about 7, and the 6-hydroxy morphinan alkaloid has an ?:? ratio of >85:15.
    Type: Grant
    Filed: August 13, 2010
    Date of Patent: October 7, 2014
    Assignee: Johnson Matthey Public Limited Company
    Inventors: George Scott Wilson, Maureen Joan Young
  • Preparation of opiate analgesics by reductive alkylation
    Patent number: 8318937
    Abstract: A process for preparing a compound of formula (A), (B) or (C): wherein P is H, CH3 or a hydroxyl protecting group; X is O, a protected ketone, OH, a protected hydroxyl group or H; Y is OH, a protected hydroxyl group or H; W is C(CH3)2OH, C(CH3)(C(CH3)3)OH or COCH3; Z is C2-C10 alkyl or C2-C10 arylalkyl; and is a single bond or a double bond, is disclosed. The process is a reductive alkylation in the presence of hydrogen and a reductive alkylation catalyst.
    Type: Grant
    Filed: February 18, 2011
    Date of Patent: November 27, 2012
    Assignee: Johnson Matthey Public Limited Company
    Inventors: Melville Mitchell, Neil Kenneth Thomson, George Scott Wilson, Neil John Goodwin, Maureen Joan Young
  • PROCESS FOR REDUCING THE 6-KETO GROUP OF A MORPHINAN ALKALOID TO THE 6-HYDROXY GROUP BY HYDROGENATION
    Publication number: 20120209002
    Abstract: The present invention relates to a process for the reduction of a 6-keto group in a morphinan alkaloid to the corresponding 6-hydroxy group, comprising hydrogenating the 6-keto group using gaseous hydrogen in the presence of a heterogenous catalyst and a solvent, to yield the 6-hydroxy morphinan alkaloid, wherein the reduction is carried out at a pH in the range of about 5 to about 7, and the 6-hydroxy morphinan alkaloid has an ?:? ratio of >85:15.
    Type: Application
    Filed: August 13, 2010
    Publication date: August 16, 2012
    Applicant: JOHNSON MATTHEY PUBLIC LIMITED COMPANY
    Inventors: George Scott Wilson, Maureen Joan Young
  • PREPARATION OF OPIATE ANALGESICS BY REDUCTIVE ALKYLATION
    Publication number: 20120046466
    Abstract: A process for preparing a compound of formula (A), (B) or (C): wherein P is H, CH3 or a hydroxyl protecting group; X is O, a protected ketone, OH, a protected hydroxyl group or H; Y is OH, a protected hydroxyl group or H; W is C(CH3)2OH, C(CH3)(C(CH3)3)OH or COCH3; Z is C2-C10 alkyl or C2-C10 arylalkyl; and is a single bond or a double bond, is disclosed. The process is a reductive alkylation in the presence of hydrogen and a reductive alkylation catalyst.
    Type: Application
    Filed: February 18, 2011
    Publication date: February 23, 2012
    Applicant: JOHNSON MATTHEY PUBLIC LIMITED COMPANY
    Inventors: Melville Mitchell, Neil Kenneth Thomson, George Scott Wilson, Neil John Goodwin, Maureen Joan Young
  • Preparation of opiate analgesics by reductive alkylation
    Patent number: 8119803
    Abstract: A process for preparing a compound of formula (A), (B) or (C): wherein P is H, CH3 or a hydroxyl protecting group; X is O, a protected ketone, OH, a protected hydroxyl group or H; Y is OH, a protected hydroxyl group or H; W is C(CH3)2OH, (CH3)(C(CH3)3)OH or COCH3; Z is C2-C10 alkyl or C2-C10 arylalkyl; and is a single bond or a double bond, is disclosed. The process includes reductive alkylation in the presence of hydrogen and a reductive alkylation catalyst.
    Type: Grant
    Filed: September 14, 2005
    Date of Patent: February 21, 2012
    Assignee: Johnson Matthey Public Limited Company
    Inventors: Melville Mitchell, Neil Kenneth Thomson, George Scott Wilson, Neil John Goodwin, Maureen Joan Young
  • PREPARATION OF OPIATE ANALGESICS BY REDUCTIVE ALKYLATION
    Publication number: 20110144341
    Abstract: A process for preparing a compound of formula (A), (B) or (C): wherein P is H, CH3 or a hydroxyl protecting group; X is O, a protected ketone, OH, a protected hydroxyl group or H; Y is OH, a protected hydroxyl group or H; W is C(CH3)2OH, C(CH3)(C(CH3)3)OH or COCH3; Z is C2-C10 alkyl or C2-C10 arylalkyl; and is a single bond or a double bond, is disclosed. The process is a reductive alkylation in the presence of hydrogen and a reductive alkylation catalyst.
    Type: Application
    Filed: February 18, 2011
    Publication date: June 16, 2011
    Applicant: JOHNSON MATTHEY PUBLIC LIMITED COMPANY
    Inventors: Melville Mitchell, Neil Kenneth Thomson, George Scott Wilson, Neil John Goodwin, Maureen Joan Young