Patents by Inventor MAUREEN NEWMAN

MAUREEN NEWMAN has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compositions and methods for controlled localized delivery of bone forming therapeutic agents
    Patent number: 10195284
    Abstract: The present invention provides compositions and methods for providing controllable local delivery of a therapeutic agent to promote bone formation. In certain embodiments, the invention is used as a treatment for a subject with osteoporosis, bone cancer or bone fracture. The invention provides a therapeutic agent that is tethered to a polymer to form a therapeutic-tethered macromer, where the therapeutic agent is controllably released from the conjugate by degradation of the tether. In certain embodiments, the therapeutic agent is an inhibitor of GSK3?. In certain embodiments, the composition of the invention is specifically targeted to a site in need of bone formation or treatment.
    Type: Grant
    Filed: September 26, 2016
    Date of Patent: February 5, 2019
    Assignee: UNIVERSITY OF ROCHESTER
    Inventors: Danielle Benoit, J. Edward Puzas, Maureen Newman, Tzong-Jen Sheu, Benjamin Frisch
  • Compositions and methods for controlled localized delivery of bone forming therapeutic agents
    Patent number: 9949950
    Abstract: The present invention provides compositions and methods for providing controllable local delivery of a therapeutic agent to promote bone formation. In certain embodiments, the invention is used as a treatment for a subject with osteoporosis, bone cancer or bone fracture. The invention provides a therapeutic agent that is tethered to a polymer to form a therapeutic-tethered macromer, where the therapeutic agent is controllably released from the conjugate by degradation of the tether. In certain embodiments, the therapeutic agent is an inhibitor of GSK3?. In certain embodiments, the composition of the invention is specifically targeted to a site in need of bone formation.
    Type: Grant
    Filed: September 14, 2015
    Date of Patent: April 24, 2018
    Assignee: UNIVERSITY OF ROCHESTER
    Inventors: Danielle Benoit, J. Edward Puzas, Maureen Newman, Tzong-Jen Sheu
  • Compositions and Methods for Controlled Localized Delivery of Bone Forming Therapeutic Agents
    Publication number: 20170072062
    Abstract: The present invention provides compositions and methods for providing controllable local delivery of a therapeutic agent to promote bone formation. In certain embodiments, the invention is used as a treatment for a subject with osteoporosis, bone cancer or bone fracture. The invention provides a therapeutic agent that is tethered to a polymer to form a therapeutic-tethered macromer, where the therapeutic agent is controllably released from the conjugate by degradation of the tether. In certain embodiments, the therapeutic agent is an inhibitor of GSK3?. In certain embodiments, the composition of the invention is specifically targeted to a site in need of bone formation or treatment.
    Type: Application
    Filed: September 26, 2016
    Publication date: March 16, 2017
    Inventors: Danielle Benoit, J. Edward Puzas, Maureen Newman, Tzong-Jen Sheu
  • Compositions and Methods for Controlled Localized Delivery of Bone Forming Therapeutic Agents
    Publication number: 20150374663
    Abstract: The present invention provides compositions and methods for providing controllable local delivery of a therapeutic agent to promote bone formation. In certain embodiments, the invention is used as a treatment for a subject with osteoporosis, bone cancer or bone fracture. The invention provides a therapeutic agent that is tethered to a polymer to form a therapeutic-tethered macromer, where the therapeutic agent is controllably released from the conjugate by degradation of the tether. In certain embodiments, the therapeutic agent is an inhibitor of GSK3?. In certain embodiments, the composition of the invention is specifically targeted to a site in need of bone formation.
    Type: Application
    Filed: September 14, 2015
    Publication date: December 31, 2015
    Applicant: UNIVERSITY OF ROCHESTER
    Inventors: DANIELLE BENOIT, EDWARD J. PUZAS, MAUREEN NEWMAN, TZONG-JEN SHEU