Patents by Inventor Maureen Ryan

Maureen Ryan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • BCMA ANTIBODIES AND USE OF SAME TO TREAT CANCER AND IMMUNOLOGICAL DISORDERS
    Publication number: 20240109975
    Abstract: The invention provides humanized antibodies that specifically bind to BCMA. The antibodies are useful for treatment and diagnoses of various cancers and immune disorders as well as detecting BCMA.
    Type: Application
    Filed: August 15, 2023
    Publication date: April 4, 2024
    Applicant: SEAGEN INC.
    Inventors: Django Sussman, Maureen Ryan, Lori Westendorf, Michael Feldhaus
  • ANTI-AVB6 ANTIBODIES AND ANTIBODY-DRUG CONJUGATES
    Publication number: 20240076383
    Abstract: Provided are novel anti-av?6 antibodies and antibody-drug conjugates and methods of using such anti-av?6 antibodies and antibody-drug conjugates to treat cancer.
    Type: Application
    Filed: October 18, 2023
    Publication date: March 7, 2024
    Applicant: SEAGEN INC.
    Inventors: Maureen Ryan, Lori Westendorf, Eric Bradley Meyer, Heather Jean Kostner
  • Anti-AVB6 antibodies and antibody-drug conjugates
    Patent number: 11827709
    Abstract: Provided are novel anti-?v?6 antibodies and antibody-drug conjugates and methods of using such anti-?v?6 antibodies and antibody-drug conjugates to treat cancer.
    Type: Grant
    Filed: December 4, 2020
    Date of Patent: November 28, 2023
    Assignee: Seagen Inc.
    Inventors: Maureen Ryan, Lori Westendorf, Eric Bradley Meyer, Heather Jean Kostner
  • BCMA antibodies and use of same to treat cancer and immunological disorders
    Patent number: 11767365
    Abstract: The invention provides humanized antibodies that specifically bind to BCMA. The antibodies are useful for treatment and diagnoses of various cancers and immune disorders as well as detecting BCMA.
    Type: Grant
    Filed: June 25, 2021
    Date of Patent: September 26, 2023
    Assignee: Seagen Inc.
    Inventors: Django Sussman, Maureen Ryan, Lori Westendorf, Michael Feldhaus
  • ANTIBODIES TO INTEGRIN AVB6 AND USE OF SAME TO TREAT CANCER
    Publication number: 20230242648
    Abstract: The invention provides antibodies that specifically bind to integrin ?v?6. The antibodies are useful for treatment and diagnoses of various cancers as well as detecting ?v?6.
    Type: Application
    Filed: February 17, 2023
    Publication date: August 3, 2023
    Applicant: Seagen Inc.
    Inventors: Maureen Ryan, Django Sussman
  • METHODS OF TREATING CANCER USING A COMBINATION OF ANTI-CD30 ANTIBODY-DRUG CONJUGATES
    Publication number: 20230190949
    Abstract: The invention provides a combination of two anti-CD30 antibody-drug conjugates, such as brentuximab vedotin and SGN-CD30C, for the treatment of cancer, such as a hematologic cancer. The invention also provides pharmaceutical compositions and kits comprising a combination of two anti-CD30 antibody-drug conjugates, such as brentuximab vedotin and SGN-CD30C, for use in the treatment of cancer.
    Type: Application
    Filed: May 12, 2021
    Publication date: June 22, 2023
    Applicant: Seagen Inc.
    Inventors: Maureen RYAN, Jessica Kelly SIMMONS
  • CAMPTOTHECIN PEPTIDE CONJUGATES
    Publication number: 20220193069
    Abstract: Provided herein are Camptothecin Conjugates, Camptothecin-Linker Compounds, Camptothecin Compounds, intermediates thereof, and method of preparing the same. Also provided herein are methods of treating cancer and autoimmune diseases with the Conjugates described herein.
    Type: Application
    Filed: October 27, 2021
    Publication date: June 23, 2022
    Inventors: Scott JEFFREY, Ryan Lyski, Maureen Ryan, Julia Cochran
  • BCMA ANTIBODIES AND USE OF SAME TO TREAT CANCER AND IMMUNOLOGICAL DISORDERS
    Publication number: 20220025062
    Abstract: The invention provides humanized antibodies that specifically bind to BCMA. The antibodies are useful for treatment and diagnoses of various cancers and immune disorders as well as detecting BCMA.
    Type: Application
    Filed: June 25, 2021
    Publication date: January 27, 2022
    Applicant: SEAGEN INC.
    Inventors: Django Sussman, Maureen Ryan, Lori Westendorf, Michael Feldhaus
  • ANTIBODIES TO INTEGRIN AVB6 AND USE OF SAME TO TREAT CANCER
    Publication number: 20210340260
    Abstract: The invention provides antibodies that specifically bind to integrin ?v?6. The antibodies are useful for treatment and diagnoses of various cancers as well as detecting ?v?6.
    Type: Application
    Filed: January 8, 2021
    Publication date: November 4, 2021
    Applicant: Seagen Inc.
    Inventors: Maureen Ryan, Django Sussman
  • BCMA antibodies and use of same to treat cancer and immunological disorders
    Patent number: 11078291
    Abstract: The invention provides humanized antibodies that specifically bind to BCMA. The antibodies are useful for treatment and diagnoses of various cancers and immune disorders as well as detecting BCMA.
    Type: Grant
    Filed: May 14, 2019
    Date of Patent: August 3, 2021
    Assignee: Seagen Inc.
    Inventors: Django Sussman, Maureen Ryan, Lori Westendorf, Michael Feldhaus
  • ANTI-AVB6 ANTIBODIES AND ANTIBODY-DRUG CONJUGATES
    Publication number: 20210198367
    Abstract: Provided are novel anti-?v?6 antibodies and antibody-drug conjugates and methods of using such anti-?v?6 antibodies and antibody-drug conjugates to treat cancer.
    Type: Application
    Filed: December 4, 2020
    Publication date: July 1, 2021
    Applicant: SEAGEN INC.
    Inventors: Maureen Ryan, Lori Westendorf, Eric Bradley Meyer, Heather Jean Kostner
  • CD33 ANTIBODIES AND USE OF SAME TO TREAT CANCER
    Publication number: 20210047404
    Abstract: The invention provides murine, chimeric, and humanized antibodies that specifically hind to CD33. The antibodies are useful for treatment and diagnoses of various cancers as well as detecting CD33.
    Type: Application
    Filed: July 29, 2020
    Publication date: February 18, 2021
    Applicant: SEATTLE GENETICS, INC.
    Inventors: May Kung Sutherland, Maureen Ryan, Django Sussman, Patrick Burke, Scott Jeffrey
  • CD33 antibodies and use of same to treat cancer
    Patent number: 10787514
    Abstract: The invention provides murine, chimeric, and humanized antibodies that specifically hind to CD33. The antibodies are useful for treatment and diagnoses of various cancers as well as detecting CD33.
    Type: Grant
    Filed: January 20, 2017
    Date of Patent: September 29, 2020
    Assignee: SEATTLE GENETICS, INC.
    Inventors: May Kung Sutherland, Maureen Ryan, Django Sussman, Patrick Burke, Scott Jeffrey
  • ANTIBODIES TO INTEGRIN AVB6 AND USE OF SAME TO TREAT CANCER
    Publication number: 20200031938
    Abstract: The invention provides antibodies that specifically bind to integrin ?v?6. The antibodies are useful for treatment and diagnoses of various cancers as well as detecting ?v?6.
    Type: Application
    Filed: September 30, 2019
    Publication date: January 30, 2020
    Applicant: SEATTLE GENETICS, INC.
    Inventors: Maureen Ryan, Django Sussman
  • BCMA ANTIBODIES AND USE OF SAME TO TREAT CANCER AND IMMUNOLOGICAL DISORDERS
    Publication number: 20200002431
    Abstract: The invention provides humanized antibodies that specifically bind to BCMA. The antibodies are useful for treatment and diagnoses of various cancers and immune disorders as well as detecting BCMA.
    Type: Application
    Filed: May 14, 2019
    Publication date: January 2, 2020
    Applicant: SEATTLE GENETICS, INC.
    Inventors: Django Sussman, Maureen Ryan, Lori Westendorf, Michael Feldhaus
  • CO-USE OF ANTI-BCMA ANTIBODY AND ANTIBODY-COUPLED T CELL RECEPTOR (ACTR) IN CANCER THERAPY AND B CELL DISORDERS
    Publication number: 20190381171
    Abstract: Disclosed herein are methods of enhancing antibody-dependent cell cytotoxicity (ADCC) in a subject comprising administering to a subject in need thereof a therapeutically effective amount of an anti-BCMA antibody and an effective amount of T lymphocytes and/or NK cells expressing an antibody-coupled T-cell receptor (ACTR) construct, which may comprises an extracellular domain with affinity and specific for the Fc portion of an immunoglobulin molecule (Ig); a transmembrane domain; optionally one or more of co-stimulatory domains, and a cytoplasmic signaling domain comprising an immunoreceptor tyrosine-based activation motif (ITAM).
    Type: Application
    Filed: February 16, 2018
    Publication date: December 19, 2019
    Applicant: UNUM THERAPEUTICS INC.
    Inventors: Heather HUET, Seth ETTENBERG, Django SUSSMAN, Tooba CHEEMA, Taylor HICKMAN, Katie O'CALLAGHAN, Maureen RYAN
  • CAMPTOTHECIN PEPTIDE CONJUGATES
    Publication number: 20190343828
    Abstract: Provided herein are Camptothecin Conjugates, Camptothecin-Linker Compounds, Camptothecin Compounds, intermediates thereof, and method of preparing the same. Also provided herein are methods of treating cancer and autoimmune diseases with the Conjugates described herein.
    Type: Application
    Filed: April 5, 2019
    Publication date: November 14, 2019
    Applicant: SEATTLE GENETICS, INC.
    Inventors: Scott Jeffrey, Ryan Lyski, Maureen Ryan, Julia Cochran
  • BCMA ANTIBODIES AND USE OF SAME TO TREAT CANCER AND IMMUNOLOGICAL DISORDERS
    Publication number: 20190194338
    Abstract: The invention provides humanized antibodies that specifically bind to BCMA. The antibodies are useful for treatment and diagnoses of various cancers and immune disorders as well as detecting BCMA.
    Type: Application
    Filed: February 16, 2017
    Publication date: June 27, 2019
    Applicant: SEATTLE GENETICS, INC.
    Inventors: Django Sussman, Maureen Ryan, Lori Westendorf, Michael Feldhaus
  • BCMA ANTIBODIES AND USE OF SAME TO TREAT CANCER AND IMMUNOLOGICAL DISORDERS
    Publication number: 20190023801
    Abstract: The invention provides humanized antibodies that specifically bind to BCMA. The antibodies are useful for treatment and diagnoses of various cancers and immune disorders as well as detecting BCMA.
    Type: Application
    Filed: October 3, 2018
    Publication date: January 24, 2019
    Applicant: SEATTLE GENETICS, INC.
    Inventors: Django Sussman, Maureen Ryan, Lori Westendorf, Michael Feldhaus
  • METHODS FOR SCREENING ANTIBODIES
    Publication number: 20170298118
    Abstract: The invention provides methods for making antibody conjugates for use in antibody screening assays and antibody conjugates produced by the claimed methods.
    Type: Application
    Filed: June 28, 2017
    Publication date: October 19, 2017
    Applicant: SEATTLE GENETICS, INC.
    Inventors: Robert Lyon, Dennis Benjamin, Maureen Ryan