Patents by Inventor Maurice Agée
Maurice Agée has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20160206972Abstract: A chromatography column design and a packing device, as well as a method for obtaining a column with a very compact and uniform bed are provided. The bed remains compact and uniform during operation of the column and during sanitization, storage and transportation of the column. The amount of hardware, particularly the hardware parts in contact with product, is minimized, especially with the implementation of an internal liner. With this internal liner, the packed bed can be separated from the column in intact form, or even prepared separately from, and outside of, the column.Type: ApplicationFiled: March 11, 2016Publication date: July 21, 2016Applicant: Bio-Rad Laboratories, Inc.Inventors: Sébastien Lefebvre, Lilian Portier, Maurice Agée
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Patent number: 9327213Abstract: A chromatography column design and a packing device, as well as a method for obtaining a column with a very compact and uniform bed are provided. The bed remains compact and uniform during operation of the column and during sanitization, storage and transportation of the column. The amount of hardware, particularly the hardware parts in contact with product, is minimized, especially with the implementation of an internal liner. With this internal liner, the packed bed can be separated from the column in intact form, or even prepared separately from, and outside of, the column.Type: GrantFiled: February 20, 2013Date of Patent: May 3, 2016Assignee: Bio-Rad Laboratories, Inc.Inventors: Sébastien Lefebvre, Lilian Portier, Maurice Agée
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Patent number: 8741135Abstract: A preparative chromatography column is equipped with one or more valves that can each be used to both inject a column packing into the column or withdraw used packing from the column, in addition to cleaning the supply and discharge lines associated with the valve itself, all by moving a movable plug within the valve body and all without protruding into the column interior. Each valve is mounted on the lateral wall of the column just above the filter plate at the column floor, and the plug is movable between a closed position in which the end surface of the plug is flush with the inner wall of the column and an open position in which the plug is recessed within the bore. Each valve has two additional ports in its valve body, positioned such that when the plug is closed, both ports are open to the valve bore, and when the plug is open, at least one of the ports is open to the bore. The position of the plug within the valve bore determines the valve function.Type: GrantFiled: April 6, 2010Date of Patent: June 3, 2014Assignee: Bio-Rad Laboratories, Inc.Inventors: Maurice Agee, Sebastien Lefebvre, Sebastien Magnaud, Philippe Vernot
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Publication number: 20130228501Abstract: A chromatography column design and a packing device, as well as a method for obtaining a column with a very compact and uniform bed are provided. The bed remains compact and uniform during operation of the column and during sanitization, storage and transportation of the column. The amount of hardware, particularly the hardware parts in contact with product, is minimized, especially with the implementation of an internal liner. With this internal liner, the packed bed can be separated from the column in intact form, or even prepared separately from, and outside of, the column.Type: ApplicationFiled: February 20, 2013Publication date: September 5, 2013Applicant: Bio-Rad Laboratories, Inc.Inventors: Sébastien Lefebvre, Lilian Portier, Maurice Agée
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Publication number: 20100193441Abstract: A preparative chromatography column is equipped with one or more valves that can each be used to both inject a column packing into the column or withdraw used packing from the column, in addition to cleaning the supply and discharge lines associated with the valve itself, all by moving a movable plug within the valve body and all without protruding into the column interior. Each valve is mounted on the lateral wall of the column just above the filter plate at the column floor, and the plug is movable between a closed position in which the end surface of the plug is flush with the inner wall of the column and an open position in which the plug is recessed within the bore. Each valve has two additional ports in its valve body, positioned such that when the plug is closed, both ports are open to the valve bore, and when the plug is open, at least one of the ports is open to the bore. The position of the plug within the valve bore determines the valve function.Type: ApplicationFiled: April 6, 2010Publication date: August 5, 2010Applicant: Bio-Rad Laboratories, Inc.Inventors: Maurice Agee, Sebastien Lefebvre, Sebastien Magnaud, Philippe Vernot
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Patent number: 7718058Abstract: A preparative chromatography column is equipped with one or more valves that can each be used to both inject a column packing into the column or withdraw used packing from the column, in addition to cleaning the supply and discharge lines associated with the valve itself, all by moving a movable plug within the valve body and all without protruding into the column interior. Each valve is mounted on the lateral wall of the column just above the filter plate at the column floor, and the plug is movable between a closed position in which the end surface of the plug is flush with the inner wall of the column and an open position in which the plug is recessed within the bore. Each valve has two additional ports in its valve body, positioned such that when the plug is closed, both ports are open to the valve bore, and when the plug is open, at least one of the ports is open to the bore. The position of the plug within the valve bore determines the valve function.Type: GrantFiled: April 23, 2008Date of Patent: May 18, 2010Assignee: Bio-Rad Laboratories, Inc.Inventors: Maurice Agee, Sebastien Lefebvre, Sebastien Magnaud, Philippe Vernot
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Publication number: 20080264837Abstract: A preparative chromatography column is equipped with one or more valves that can each be used to both inject a column packing into the column or withdraw used packing from the column, in addition to cleaning the supply and discharge lines associated with the valve itself, all by moving a movable plug within the valve body and all without protruding into the column interior. Each valve is mounted on the lateral wall of the column just above the filter plate at the column floor, and the plug is movable between a closed position in which the end surface of the plug is flush with the inner wall of the column and an open position in which the plug is recessed within the bore. Each valve has two additional ports in its valve body, positioned such that when the plug is closed, both ports are open to the valve bore, and when the plug is open, at least one of the ports is open to the bore. The position of the plug within the valve bore determines the valve function.Type: ApplicationFiled: April 23, 2008Publication date: October 30, 2008Applicant: Bio-Rad Laboratories, Inc.Inventors: Maurice Agee, Sebastien Lefebvre, Sebastien Magnaud, Philippe Vernot