Patents by Inventor Maurice Chassaigne

Maurice Chassaigne has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Apparatus for encapsulating biological active substances into erythrocytes
    Patent number: 4752586
    Abstract: This invention relates to a process for the encapsulation in human or animal erythrocytes of at least one substance having a biological activity, characterized in that the primary compartment of at least one dialysis element is continuously supplied with an aqueous suspension of erythrocytes, the secondary compartment of the dialysis element contains an aqueous solution which is hypotonic with respect to the erythrocyte suspension in order to lyse the erythrocytes, the erythrocyte lysate is in contact with said substance having a biological activity and, in order to reseal the membrane of the erythrocytes, the osmotic and/or oncotic pressure of the erythrocyte lysate is increased after it has been brought into contact with said substance having a biological activity.
    Type: Grant
    Filed: November 20, 1986
    Date of Patent: June 21, 1988
    Assignees: Centre National de la Recherche Scientifique, Centre Hospitalier Regional de Tours, Studiengesellschaft Kohle mbH
    Inventors: Claude Ropars, Yves Nicolau, Maurice Chassaigne
  • Encapsulating biological active substances into erythrocytes
    Patent number: 4652449
    Abstract: This invention relates to a process for the encapsulation in human or animal erythrocytes of at least one substance having a biological activity, characterized in that the primary compartment of at least one dialysis element is continuously supplied with an aqueous suspension of erythrocytes, the secondary compartment of the dialysis element contains an aqueous solution which is hypotonic with respect to the erythrocyte suspension in order to lyse the erythrocytes, the erythrocyte lysate is in contact with said substance having a biological activity and, in order to reseal the membrane of the erythrocytes, the osmotic and/or oncotic pressure of the erythrocyte lysate is increased after it has been brought into contact with said substance having a biological activity.
    Type: Grant
    Filed: October 27, 1983
    Date of Patent: March 24, 1987
    Assignees: Centre National de la Recherche Scientifique (CNRS), Centre Hospitalier Regional de Tours, Studiengesellschaft Kohle MBH
    Inventors: Claude Ropars, Yves C. Nicolau, Maurice Chassaigne