Patents by Inventor Maurice Joullie

Maurice Joullie has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 4252804
    Abstract: Compounds of the formula I ##STR1## wherein m and n are 0, 1 or 2, X represents oxygen, imino, benzylimino, or morpholinoethylimino, Y represents CO, CONH, COO or SO.sub.2, and NR.sub.1 R.sub.2 represents a dimethylamino, diethylamino, dipropylamino, dibutylamino, allylamino, isobutenylamino, cyclopentylamino, cyclohexylamino, cycloheptylamino, cyclooctylamino, N-methyl N-cyclopentylamino, N-methyl N-cyclohexylamino, N-allyl N-cyclohexylamino, adamantylamino, diethoxyethylamino, dimethylaminoethylamino, dimethylaminopropylamino, N-methyl N-dimethylaminopropyl-amino, benzylamino, 3,4,5-trimethoxybenzylamino, phenethylamino, p-chlorophenethylamino, tetrahydrofurfurylamino, tetrahydropyranylmethylamino, pyrrolidino, isoxazolidinyl, piperidino, 4-hydroxypiperidino, 4-m-chlorophenyl-4-hydroxypiperidino, homopiperidino, 1,2,3,6-tetrahydropyridyl, morpholino, 2-methylmorpholino, 2,6-dimethylmorpholino, 2-morpholinoethylamino, thiamorpholino, piperazino, 4-methylpiperazino, 4-(.alpha.
    Type: Grant
    Filed: January 13, 1978
    Date of Patent: February 24, 1981
    Assignee: Metabio-Joullie
    Inventors: Maurice Joullie, Gabriel Maillard, Lucien Lakah, Christian J. M. Warolin
  • Patent number: 4203986
    Abstract: Compounds of the formula I ##STR1## wherein R.sub.1 represents a hydrogen or fluorine atom, and R.sub.2 represents an alkyl group containing 2 to 6 carbon atoms, or a cycloalkyl or cycloalkyl-alkyl group containing 5 to 8 carbon atoms, each of these groups being substituted by one or two hydroxy groups or an oxo group and, if desired, also by a 4-(m-trifluoromethylphenyl)-piperazino or 4-(3-trifluoromethyl-4-fluoro-phenyl)-piperazino group with the proviso that, when R.sub.1 represents a hydrogen atom, R.sub.2 does not represent a monohydroxyalkyl group, and their pharmaceutically acceptable acid addition salts are novel and have therapeutic use, notably in the region of the central nervous system and in the cardiovascular region.
    Type: Grant
    Filed: January 13, 1978
    Date of Patent: May 20, 1980
    Assignee: Metabio-Joullie
    Inventors: Maurice Joullie, Gabriel Maillard, Lucien Lakah, Christian J. M. Warolin, Yves R. A. Pascal
  • Patent number: 4078090
    Abstract: (Carboxymethylthio)acetic acid and its salts provide a mucolytic effect, and the calcium and magnesium salts are of special interest for the field of immune response reactions.
    Type: Grant
    Filed: October 12, 1976
    Date of Patent: March 7, 1978
    Assignee: S.A. Joullie International
    Inventors: Lucien Lakah, Gabriel Maillard, Maurice Joullie, Christian Jean Marie Warolin
  • Patent number: 4078082
    Abstract: (Carboxyalkylthio)acetic acid and their salts provide a mucolytic effect, and the calcium and magnesium salts are of a special interest for the field of immune response reactions.
    Type: Grant
    Filed: October 12, 1976
    Date of Patent: March 7, 1978
    Assignee: S.A. Joullie International
    Inventors: Lucien Lakah, Gabriel Maillard, Maurice Joullie, Christian Jean Marie Warolin
  • Patent number: 4065575
    Abstract: 4-Chromanone derivatives of the formula: ##STR1## wherein R represents alkyl of 1 through 6 carbon atoms or alkoxyalkyl of 2 through 6 carbon atoms, are new compounds possessing pharmacological properties and are useful inter alia as vasodilators.
    Type: Grant
    Filed: February 20, 1976
    Date of Patent: December 27, 1977
    Assignee: Joullie International
    Inventors: Maurice Joullie, Gabriel Maillard, Lucien Lakah, Christian Jean Marie Warolin
  • Patent number: 4054669
    Abstract: 1-Hydroxy-4-(3'-m.menthen-4'-yl)-benzene, 1-hydroxy-3-methyl-4-(3'-m.menthen-4'-yl)-6-isopropyl-benzene and their sulfonates have antiviral activity against influenza virus and antibacterial activity against gram-positive bacteria.
    Type: Grant
    Filed: January 2, 1976
    Date of Patent: October 18, 1977
    Assignees: Les Derives Resiniques et Terpeniques, S.A. Joullie International
    Inventors: Bernard Lahourcade, Christiane Hirigoyen, Maurice Joullie, Gabriel Maillard, Lucien Lakah, Christian Warolin
  • Patent number: 3950387
    Abstract: S-substituted cysteines, alkyl esters of S-substituted cysteines and S-substituted glutathiones in which the substituent on the S atom is allyl, geranyl, cinnamyl, benzylidene-3-butyl, 1-(para-chlorophenyl)ethyl and (pyridyl-3)methyl but excluding S-allyl cysteine bring about a reduction in atheromatic deposits in the aorta of test animals as well as a reduction in hypercholesterolemia and are of low toxicity. They may be used by the conventional routes for the treatment of human atheromatic conditions and disorders of the lipid metabolism.
    Type: Grant
    Filed: June 7, 1973
    Date of Patent: April 13, 1976
    Assignee: Recherches Pharmaceutiques et Scientifiques
    Inventors: Maurice Joullie, Lucien Lakah, Gabriel Maillard, Pierre Muller