Patents by Inventor Maurice Moloney

Maurice Moloney has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20230020704
    Abstract: A method for an aerosol delivery device, may include storing, during use of the aerosol delivery device and in a memory of the aerosol delivery device, information recording usage characteristics of the aerosol delivery device. The method may further comprise creating, using a wireless communication interface of the aerosol delivery device, a connectionless-state advertising packet that includes information relating to an identity and advertising state of the aerosol delivery device and a first set of information recording usage characteristics of the aerosol delivery device from the memory; and transmitting the advertising packet via the wireless communication interface.
    Type: Application
    Filed: September 26, 2022
    Publication date: January 19, 2023
    Inventors: Robert KERSEY, Darryl BAKER, Patrick MOLONEY, Maurice EZEOKE
  • Patent number: 11510040
    Abstract: A method for an aerosol delivery device may include storing, during use of the aerosol delivery device and in a memory of the aerosol delivery device, information recording usage characteristics of the aerosol delivery device. The method may further include creating, using a wireless communication interface of the aerosol delivery device, a connectionless-state advertising packet that includes information relating to an identity and advertising state of the aerosol delivery device and a first set of information recording usage characteristics of the aerosol delivery device from the memory; and transmitting the advertising packet via the wireless communication interface.
    Type: Grant
    Filed: May 1, 2018
    Date of Patent: November 22, 2022
    Assignee: Nicoventures Trading Limited
    Inventors: Robert Kersey, Darryl Baker, Patrick Moloney, Maurice Ezeoke
  • Publication number: 20220240070
    Abstract: A method for an aerosol delivery device may include storing, during use of the aerosol delivery device, information recording usage characteristics of the aerosol delivery device. The method may further comprise creating, using a wireless communication interface of the aerosol delivery device, a connectionless-state advertising packet that includes information relating to an identity and advertising state of the aerosol delivery device and a first set of information recording usage characteristics of the aerosol delivery device from the memory; and transmitting the advertising packet via the wireless communication interface.
    Type: Application
    Filed: April 15, 2022
    Publication date: July 28, 2022
    Inventors: Robert KERSEY, Darryl BAKER, Patrick MOLONEY, Maurice EZEOKE
  • Publication number: 20090197337
    Abstract: Improved methods for the production of multimeric-protein-complexes, such as redox proteins and immunoglobins, in association with oil bodies are described. The redox protein is enzymatically active when prepared in association with the oil bodies. Also provided are related nucleic acids, proteins, cells, plants, and compositions.
    Type: Application
    Filed: December 19, 2001
    Publication date: August 6, 2009
    Inventors: Gijs Van Rooijen, Harm Deckers, Steven Briggs, Bipin Kumar Dalmia, Greg Del Val, Steve Zaplachinski, Maurice Moloney, Peter Bernard Heifetz
  • Patent number: 7501265
    Abstract: An improved method for recovering recombinantly produced polypeptides is described. The method involves expressing the recombinant polypeptide as a fusion protein with a pro-peptide. The pro-peptide-polypeptide fusion protein can be cleaved and the recombinant polypeptide released under the appropriate conditions.
    Type: Grant
    Filed: April 23, 1998
    Date of Patent: March 10, 2009
    Assignee: SemBioSys Genetics Inc.
    Inventors: Maurice Moloney, Joenel Alcantara, Gijs Van Rooijen
  • Patent number: 7332587
    Abstract: A method for the separation of a target molecule from a mixture is described. The method employs oil bodies and their associated proteins as affinity matrices for the selective, non-covalent binding of desired target molecules. The oil body proteins may be genetically fused to a ligand having specificity for the desired target molecule. Native oil body proteins can also be used in conjunction with an oil body protein specific ligand such as an antibody or an oil body binding protein. The method allows the separation and recovery of the desired target molecules due to the difference in densities between oil bodies and aqueous solutions.
    Type: Grant
    Filed: October 1, 2002
    Date of Patent: February 19, 2008
    Assignee: SemBioSys Genetics Inc.
    Inventors: Maurice Moloney, Joseph Boothe, Gijs Van Rooijen
  • Publication number: 20070245431
    Abstract: Disclosed are novel acyl-CoA synthetases and novel acyltransferases, nucleic acid molecules encoding the same, recombinant nucleic acid molecules and recombinant host cells comprising such nucleic acid molecules, genetically modified organisms (microorganisms and plants) comprising the same, and methods of making and using the same. Also disclosed are genetically modified organisms (e.g., plants, microorganisms) that have been genetically modified to express a PKS-like system for the production of PUFAs (a PUFA PKS system or PUFA synthase), wherein the organisms have been modified to express an acyl-CoA synthetase, to express an acyl transferase, to delete or inactivate a fatty acid synthase (FAS) expressed by the organism, to reduce competition for malonyl CoA with the PUFA synthase or to increase the level of malonyl CoA in the plant or plant cell, and in one aspect, to inhibit KASII or KASIII.
    Type: Application
    Filed: March 15, 2007
    Publication date: October 18, 2007
    Applicants: MARTEK BIOSCIENCES CORPORATION, SEMBIOSYS GENETICS INC.
    Inventors: James Metz, Jerry Kuner, James Lippmeier, Maurice Moloney, Cory Nykiforuk
  • Publication number: 20070006343
    Abstract: The present invention describes novel polypeptide structures based on oleosin molecules which are capable of being targeted to oil bodies in plants. The modified oleosin polypeptides are obtained by performing modifications in the hydrophobic domain encoding sequence of an oleosin cDNA. The present invention describes methods to obtain such polypeptides in vivo. The novel oleosins may be used to deliver a recombinant (non-oleosin) protein to oil bodies.
    Type: Application
    Filed: June 18, 2004
    Publication date: January 4, 2007
    Applicant: SEMBIOSYS GENETICS INC
    Inventors: Maurice Moloney, Rodrigo Siloto
  • Publication number: 20060233816
    Abstract: The present invention relates to the use of oil bodies as a vaccine adjuvant and delivery system for administration of vaccines by parenteral, mucosal (oral, nasal, pulmonary) and transdermal routes. In addition, the present invention relates to methods of eliciting an immune response in an animal by administering oil body-antigen complexes to said mammal. Finally, the present invention relates to methods of preparing oil body-antigen complexes.
    Type: Application
    Filed: May 22, 2006
    Publication date: October 19, 2006
    Inventors: Anthony Schryvers, Wendy Hutchins, Maurice Moloney, Joenel Alcantara
  • Patent number: 7098383
    Abstract: Improved methods for the production of multimeric-protein-complexes, such as redox proteins and immunoglobulins, in association with oil bodies are described. The redox protein is enzymatically active when prepared in association with the oil bodies. Also provided are related nucleic acids, proteins, cells, plants, and compositions.
    Type: Grant
    Filed: June 21, 2002
    Date of Patent: August 29, 2006
    Assignee: SemBioSys Genetics Inc.
    Inventors: Steven Szarka, Gijs Van Rooijen, Maurice Moloney
  • Publication number: 20050172359
    Abstract: Methods for the production of an apolipoprotein in plants are described. In one embodiment, the present invention provides a method for the expression of apolipoprotein in plants comprising: (a) providing a chimeric nucleic acid construct comprising in the 5? to 3? direction of transcription as operably linked components: (i) a nucleic acid sequence capable of controlling expression in plant cells; and (ii) a nucleic acid sequence encoding an apolipoprotein polypeptide; (b) introducing the chimeric nucleic acid construct into a plant cell; and growing the plant cell into a mature plant capable of setting seed wherein the seed expresses apolipoprotein.
    Type: Application
    Filed: November 15, 2004
    Publication date: August 4, 2005
    Inventors: Maurice Moloney, Alexandra Reid
  • Patent number: 6924363
    Abstract: A method for the separation of a target molecule from a mixture is described. The method employs oil bodies and their associated proteins as affinity matrices for the selective, non-covalent binding of desired target molecules. The oil body proteins may be genetically fused to a ligand having specificity for the desired target molecule. Native oil body proteins can also be used in conjunction with an oil body protein specific ligand such as an antibody or an oil body binding protein. The method allows the separation and recovery of the desired target molecules due to the difference in densities between oil bodies and aqueous solutions.
    Type: Grant
    Filed: November 7, 2000
    Date of Patent: August 2, 2005
    Assignee: SemBioSys Genetics Inc.
    Inventors: Maurice Moloney, Joseph Boothe, Gijs van Rooijen
  • Publication number: 20050106157
    Abstract: The present invention provides novel adjuvants which comprise oil bodies. The invention also provides vaccine or immunogenic formulations comprising oil bodies and an antigen and methods for preparing the vaccine or immunogenic formulations and the use of the vaccine or immunogenic formulations to elicit an immune response.
    Type: Application
    Filed: January 15, 2004
    Publication date: May 19, 2005
    Inventors: Harm Deckers, Gijs Rooijen, Joseph Boothe, Janis Goll, Maurice Moloney, Anthony Schryvers, Joenel Alcantara, Wendy Hutchins
  • Publication number: 20050039235
    Abstract: Methods for the production of insulin in plants are described. In one embodiment, the present invention provides a method for the expression of insulin in plants comprising: (a) providing a chimeric nucleic acid construct comprising in the 5? to 3? direction of transcription as operably linked components: (i) a nucleic acid sequence capable of controlling expression in plant seed cells; and (ii) a nucleic acid sequence encoding an insulin polypeptide; (b) introducing the chimeric nucleic acid construct into a plant cell; and (c) growing the plant cell into a mature plant capable of setting seed wherein the seed expresses insulin.
    Type: Application
    Filed: June 17, 2004
    Publication date: February 17, 2005
    Inventors: Maurice Moloney, Joseph Boothe, Richard Keon, Cory Nykiforuk, Gijs Van Rooijen
  • Publication number: 20030233677
    Abstract: Methods and systems to modify fatty acid biosynthesis and oxidation in plants to make new polymers are provided. Two enzymes are essential: a hydratase such as D-specific enoyl-CoA hydratase, for example, the hydratase obtained from Aeromonas caviae, and a &bgr;-oxidation enzyme system. Some plants have a &bgr;-oxidation enzyme system which is sufficient to modify polymer synthesis when the plants are engineered to express the hydratase. Examples demonstrate production of polymer by expression of these enzymes in transgenic plants. Examples also demonstrate that modifications in fatty acid biosynthesis can be used to alter plant phenotypes, decreasing or eliminating seed production and increasing green plant biomass, as well as producing polyhydroxyalkanoates.
    Type: Application
    Filed: May 28, 2003
    Publication date: December 18, 2003
    Applicant: Metabolix, Inc.
    Inventors: Oliver P. Peoples, Maurice Moloney, Nii Patterson, Kristi D. Snell
  • Patent number: 6586658
    Abstract: Methods and systems to modify fatty acid biosynthesis and oxidation in plants to make new polymers are provided. Two enzymes are essential: a hydratase such as D-specific enoyl-CoA hydratase, for example, the hydratase obtained from Aeromonas caviae, and a &bgr;-oxidation enzyme system. Some plants have a &bgr;-oxidation enzyme system which is sufficient to modify polymer synthesis when the plants are engineered to express the hydratase. Examples demonstrate production of polymer by expression of these enzymes in transgenic plants. Examples also demonstrate that modifications in fatty acid biosynthesis can be used to alter plant phenotypes, decreasing or eliminating seed production and increasing green plant biomass, as well as producing polyhydroxyalkanoates.
    Type: Grant
    Filed: September 3, 1999
    Date of Patent: July 1, 2003
    Assignee: Metabolix, Inc.
    Inventors: Oliver P. Peoples, Maurice Moloney, Nii Patterson, Kristi D. Snell
  • Publication number: 20030096320
    Abstract: A method for the separation of a target molecule from a mixture is described. The method employs oil bodies and their associated proteins as affinity matrices for the selective, non-covalent binding of desired target molecules. The oil body proteins may be genetically fused to a ligand having specificity for the desired target molecule. Native oil body proteins can also be used in conjunction with an oil body protein specific ligand such as an antibody or an oil body binding protein. The method allows the separation and recovery of the desired target molecules due to the difference in densities between oil bodies and aqueous solutions.
    Type: Application
    Filed: October 1, 2002
    Publication date: May 22, 2003
    Applicant: SemBioSys Genetics Inc.
    Inventors: Maurice Moloney, Joseph Boothe, Gijs Van Rooijen
  • Publication number: 20030093832
    Abstract: Improved methods for the production of multimeric-protein-complexes, such as redox proteins and immunoglobulins, in association with oil bodies are described. The redox protein is enzymatically active when prepared in association with the oil bodies. Also provided are related nucleic acids, proteins, cells, plants, and compositions.
    Type: Application
    Filed: June 21, 2002
    Publication date: May 15, 2003
    Inventors: Steven Szarka, Gijs Van Rooijen, Maurice Moloney
  • Publication number: 20030059910
    Abstract: A method for the separation of a target molecule from a mixture is described. The method employs oil bodies and their associated proteins as affinity matrices for the selective, non-covalent binding of desired target molecules. The oil body proteins may be genetically fused to a ligand having specificity for the desired target molecule. Native oil body proteins can also be used in conjunction with an oil body protein specific ligand such as an antibody or an oil body binding protein. The method allows the separation and recovery of the desired target molecules due to the difference in densities between oil bodies and aqueous solutions.
    Type: Application
    Filed: October 1, 2002
    Publication date: March 27, 2003
    Applicant: SemBioSys Genetics Inc.
    Inventors: Maurice Moloney, Joseph Boothe, Gijs Van Rooijen
  • Patent number: 6509453
    Abstract: A method for the separation of a target molecule from a mixture is described. The method employs oil bodies and their associated proteins as affinity matrices for the selective, non-covalent binding of desired target molecules. The oil body proteins may be genetically fused to a ligand having specificity for the desired target molecule. Native oil body proteins can also be used in conjunction with an oil body protein specific ligand such as an antibody or an oil body binding protein.
    Type: Grant
    Filed: August 27, 1999
    Date of Patent: January 21, 2003
    Assignee: SemBioSys Genetics Inc.
    Inventors: Maurice Moloney, Joseph Boothe, Gijs Van Rooijen