Abstract: Systems and methods are provided for computer aided phenotyping of biological samples with fibrillar structures. A digital image indicates presence of proteins or cells that can form fibrillar structures in the biological tissue sample. The image is processed to quantify parameters, each parameter describing a feature of the proteins or cells fibers that is expected to be different for different phenotypes of interest of their structure. At least some features are tissue level features that describe macroscopic characteristics, morphometric level features that describe morphometric characteristics of the fibrillar structures, and texture level features that describe an organization of the fibrillar structures.

Abstract: Systems and methods are provided for computer aided phenotyping of fibrosis-related conditions. A digital image indicates presence of collagens in a biological tissue sample. The image is processed to quantify parameters, each parameter describing a feature of the collagens that is expected to be different for different phenotypes of fibrosis. At least some features are tissue level features that describe macroscopic characteristics of the collagens, morphometric level features that describe morphometric characteristics of the collagens, and texture level features that describe an organization of the collagens. At least some of the plurality of parameters are statistics associated with histograms corresponding to distributions of the associated parameters across at least some of the digital image. At least some of the plurality of parameters are combined to obtain one or more composite scores that quantify a phenotype of fibrosis for the biological tissue sample.

Abstract: Systems and methods are provided for computer aided phenotyping of fibrosis-related conditions. A digital image indicates presence of collagens in a biological tissue sample. The image is processed to quantify parameters, each parameter describing a feature of the collagens that is expected to be different for different phenotypes of fibrosis. At least some features are tissue level features that describe macroscopic characteristics of the collagens, morphometric level features that describe morphometric characteristics of the collagens, and texture level features that describe an organization of the collagens. At least some of the plurality of parameters are statistics associated with histograms corresponding to distributions of the associated parameters across at least some of the digital image. At least some of the plurality of parameters are combined to obtain one or more composite scores that quantify a phenotype of fibrosis for the biological tissue sample.

Abstract: Systems and methods are provided for computer aided phenotyping of fibrosis-related conditions. A digital image indicates presence of collagens in a biological tissue sample. The image is processed to quantify parameters, each parameter describing a feature of the collagens that is expected to be different for different phenotypes of fibrosis. At least some features are tissue level features that describe macroscopic characteristics of the collagens, morphometric level features that describe morphometric characteristics of the collagens, and texture level features that describe an organization of the collagens. At least some of the plurality of parameters are statistics associated with histograms corresponding to distributions of the associated parameters across at least some of the digital image. At least some of the plurality of parameters are combined to obtain one or more composite scores that quantify a phenotype of fibrosis for the biological tissue sample.

Abstract: Systems and methods are provided for computer aided phenotyping of fibrosis-related conditions. A digital image indicates presence of collagens in a biological tissue sample. The image is processed to quantify parameters, each parameter describing a feature of the collagens that is expected to be different for different phenotypes of fibrosis. At least some features are tissue level features that describe macroscopic characteristics of the collagens, morphometric level features that describe morphometric characteristics of the collagens, and texture level features that describe an organization of the collagens. At least some of the plurality of parameters are statistics associated with histograms corresponding to distributions of the associated parameters across at least some of the digital image. At least some of the plurality of parameters are combined to obtain one or more composite scores that quantify a phenotype of fibrosis for the biological tissue sample.

Abstract: The dispenser comprises a reservoir and a pump that is activated by a tappet, comprising a pump body that includes a tubular part with a smaller gauge than that of the reservoir, covering the piston, and an annular spacer by means of which it is tightly mounted against the inner wall of the reservoir such as to define an annular chamber for the product, which communicates with a dosage chamber located in the bottom of the reservoir.

Abstract: The dispenser comprises a reservoir and a pump that is activated by a tappet, comprising a pump body that includes a tubular part with a smaller gauge than that of the reservoir, covering the piston, and an annular spacer by means of which it is tightly mounted against the inner wall of the reservoir such as to define an annular chamber for the product, which communicates with a dosage chamber located in the bottom of the reservoir.

Abstract: The invention provides a dispenser for dispensing liquids from a receptacle, the dispenser having a cylindrical and conical body containing a measuring chamber closed at its bottom end by an admission valve and at its top end by a piston provided with a delivery valve and a delivery tube capped by a pushbutton, the body being the result of assembling together two independent elements: a top element carrying the piston and provided with a cylindrical skirt; and a bottom element provided with a sleeve for co-operating with the skirt by leaktight radial clamping so as to define the wall of the measuring chamber, the bottom element being provided with a bushing extending the sleeve coaxially downwards and engaged with leaktight radial clamping inside the neck of the receptacle.

Abstract: A peelable film comprising: (A) a core layer comprising an olefin polymer; (B) a skin layer on at least one surface of the core layer, the skin layer comprising: (i) a blend of a butylene polymer with another olefin polymer; or (ii) a polymer of butylene and at least one other olefin; and (C) a coating layer on the skin layer.

Abstract: An opaque, biaxially oriented multi-layer polymeric film structure of reduced surface coefficient of friction.

Abstract: An opaque, biaxially oriented polymeric film structure, produced by orienting the film to a degree which provides low light transmission and improved machinability.

Abstract: A multilayer opaque, biaxially oriented polymeric film structure.