Patents by Inventor Maurice R. C. Needham

Maurice R. C. Needham has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Expression systems
    Patent number: 5538885
    Abstract: Expression systems which comprise a mammalian host, such as erythroid cells, transformed with a vector which comprises a promoter, a DNA sequence which codes for a desired polypeptide and a dominant control region. The vectors and methods for preparing polypeptides using the expression systems are also described. In a preferred embodiment, the vector contains cDNA for the desired polypeptide and a sequence which is capable of stabilising mRNA produced from the cDNA. The expression systems are particularly efficient and are capable of secreting the desired polypeptide.
    Type: Grant
    Filed: January 27, 1994
    Date of Patent: July 23, 1996
    Assignee: Imperial Chemical Industries PLC
    Inventors: Melvyn Hollis, Maurice R. C. Needham, Clare Gooding, Franklin G. Grosveld, Michael Antoniou