Abstract: A pacemaker has a housing and a therapy delivery circuit enclosed by the housing for generating pacing pulses for delivery to a patient's heart. An electrically insulative distal member is coupled directly to the housing and at least one non-tissue piercing cathode electrode is coupled directly to the insulative distal member. A tissue piercing electrode extends away from the housing.

Abstract: Casings for retaining adapter connector modules and implantable electrical devices, and adapter assemblies for retaining implantable medical devices, include first and second opposing plates spaced apart by a gap configured to retain the devices such that sides of the devices are in confronting engagement with the first and second plates when placed the device is held in the gap. The first and second plates may be biased towards one another to assist in retaining the device in the gap. The device and adapter connector module may be arranged such that their thicknesses do not overlap. For example, the device and adapter connector module may be arranged such that a bottom perimeter edge of the adapter connector module abuts or is spaced apart from a top perimeter edge of the device.

Abstract: A pacemaker has a housing and a therapy delivery circuit enclosed by the housing for generating pacing pulses for delivery to a patient's heart. An electrically insulative distal member is coupled directly to the housing and at least one non-tissue piercing cathode electrode is coupled directly to the insulative distal member. A tissue piercing electrode extends away from the housing.

Abstract: A pacemaker has a housing and a therapy delivery circuit enclosed by the housing for generating pacing pulses for delivery to a patient's heart. An electrically insulative distal member is coupled directly to the housing and at least one non-tissue piercing cathode electrode is coupled directly to the insulative distal member. A tissue piercing electrode extends away from the housing.

Abstract: A pacemaker has a housing and a therapy delivery circuit enclosed by the housing for generating pacing pulses for delivery to a patient's heart. An electrically insulative distal member is coupled directly to the housing and at least one non-tissue piercing cathode electrode is coupled directly to the insulative distal member. A tissue piercing electrode extends away from the housing.

Abstract: A prosthetic heart valve is disclosed that is deformable between collapsed, radially uncompressed, and target conditions. The prosthetic heart valve includes an inner frame, at least one leaflet, and a braided wire mesh arranged outside and coupled to the inner frame by a coupling portion. The braided wire mesh includes a body portion between the coupling portion and a flared portion. In the radially uncompressed condition, the prosthetic heart valve forms a cavity surrounded by the braided wire mesh and the inner frame. In the target condition, only a part of the length of the body portion is radially compressed along an axis extending from an upstream side to a downstream side. In the collapsed condition, the inner frame and braided wire mesh are radially collapsed over their entire length. In the radially uncompressed condition, the body portion is tubular and the braided wire mesh has a rotationally symmetric circumference.

Abstract: Apparatus and methods for placement of electrodes into selected tissue, such as the septal wall separating the left and right ventricles, with, in some cases, access to the septal wall from the right ventricle. Torque sleeves may be used to provide for rotation as needed.

Abstract: A pacemaker has a housing and a therapy delivery circuit enclosed by the housing for generating pacing pulses for delivery to a patient's heart. An electrically insulative distal member is coupled directly to the housing and at least one non-tissue piercing cathode electrode is coupled directly to the insulative distal member. A tissue piercing electrode extends away from the housing.

Abstract: A pacemaker has a housing and a therapy delivery circuit enclosed by the housing for generating pacing pulses for delivery to a patient's heart. An electrically insulative distal member is coupled directly to the housing and at least one non-tissue piercing cathode electrode is coupled directly to the insulative distal member. A tissue piercing electrode extends away from the housing.

Abstract: Casings for retaining adapter connector modules and implantable electrical devices, and adapter assemblies for retaining implantable medical devices, include first and second opposing plates spaced apart by a gap configured to retain the devices such that sides of the devices are in confronting engagement with the first and second plates when placed the device is held in the gap. The first and second plates may be biased towards one another to assist in retaining the device in the gap. The device and adapter connector module may be arranged such that their thicknesses do not overlap. For example, the device and adapter connector module may be arranged such that a bottom perimeter edge of the adapter connector module abuts or is spaced apart from a top perimeter edge of the device.

Abstract: A dilation catheter having a balloon inflation shaft with an inflation lumen into which a stiffening wire extends and a guidewire shaft having a guide wire lumen adjacent to the balloon. The stiffening wire includes at least two stepped diameter reductions along its length to vary stiffness from a stiff proximal end providing improved pushability to a less stiff distal end providing improved trackability. A manifold at the inflation shaft proximal end includes a handle for adjusting the distance the stiffening wire extends into the inflation lumen to allow stiffness to be optimized. The handle includes a tubular flange frictionally engaging the manifold to prevent inadvertent handle movement. The balloon inflation shaft and guidewire shafts are bonded together in a manner producing an assembly having a circular cross section for improved connection to a circular balloon and improved catheter performance.