Abstract: A gas sensor assembly includes a housing; an inlet assembly configured to carry a gaseous composition having a volatile organic compound into the housing; and an outlet assembly configured to carry the gaseous composition from the housing. The gas sensor assembly also includes an ultraviolet light source disposed within the housing and a gas sensor disposed within the housing and configured to sense an amount of the volatile organic compound.

Abstract: Disclosed is a downhole tool comprising a fast hybrid telemetry module, and electronics module, and an acoustic flow meter tool module. Suitably, the fast hybrid telemetry module, the electronics module, and the acoustic flow meter tool module are assembled in series. Initially, the acoustic flow meter tool module is preferably provided for regular measurement of fluid temperature, fluid velocity, and fluid density in downhole oilfield production applications. Preferably, the electronics module is provided for data processing and self-compensation of the acoustic flow meter tool module (i.e., automated adjustment of acoustic wave energy and signal conditioning settings to perform flow rate measurements in a wide range of well bore conditions). Finally, the fast hybrid telemetry module is configured for bidirectional data transmission between the downhole tool and a surface data acquisition and monitoring station.

Abstract: A gas sensor assembly includes a housing; an inlet assembly configured to carry a gaseous composition having a volatile organic compound into the housing; and an outlet assembly configured to carry the gaseous composition from the housing. The gas sensor assembly also includes an ultraviolet light source disposed within the housing and a gas sensor disposed within the housing and configured to sense an amount of the volatile organic compound.

Abstract: Disclosed is a downhole tool comprising a fast hybrid telemetry module, and electronics module, and an acoustic flow meter tool module. Suitably, the fast hybrid telemetry module, the electronics module, and the acoustic flow meter tool module are assembled in series. Initially, the acoustic flow meter tool module is preferably provided for regular measurement of fluid temperature, fluid velocity, and fluid density in downhole oilfield production applications. Preferably, the electronics module is provided for data processing and self-compensation of the acoustic flow meter tool module (i.e., automated adjustment of acoustic wave energy and signal conditioning settings to perform flow rate measurements in a wide range of well bore conditions). Finally, the fast hybrid telemetry module is configured for bidirectional data transmission between the downhole tool and a surface data acquisition and monitoring station.

Abstract: User interfaces of a software platform that generates transformed code from source code enable interaction with the codes. In various embodiments, the software platform may store the source code and the transformed code in a data store. The transformed code is a transformation of the source code by at least one business semantic preserving code transform. The at least one business semantic preserving transform causes an execution of the transformed code in a new execution scenario to produce an identical semantic effect as an execution of the source code in an old execution scenario. Subsequently, the software platform may cause a display of a user interface of the application on a display device. The user interface may provide one or more user command items for manipulating at least one of the source code or the transformed code stored in the data store.

Abstract: Techniques to perform code separation with semantic guarantees are described. When porting a software application to a different target architecture and potentially to a different set of platforms and programming languages, application functionality will change based at least to accommodate architectural differences. However, business logic should be guaranteed to be semantically preserved, efficiency optimized to the platform benefits and limitations. Code separation identifies candidate components, associates the candidate components with a component classification or type, and automates the determining of which of the candidate components are to be associated with various portions of the target architecture. Automated code separation may include various inference algorithms to determine which components are to be associated with a component type. Also described are various use cases for code separation.

Abstract: Techniques to automatically port applications to a mobile infrastructure using code separation with semantic guarantees are disclosed. Porting enterprise applications from to a target architecture another is effected via separating code into constituent layers of the target architecture. To preserve semantics, code transformations are enforced via an abstract syntax tree structure. The generated code may have various code wrappers and/or infrastructure elements so the ported application will operate in the target architecture. Various techniques are disclosed regarding specific code wrappers and/or infrastructure elements to address operating issues including, but not limited to, architectural issues, network latency, framework changes, regulatory issues.

Abstract: User interfaces of a software platform that generates transformed code from source code enable interaction with the codes. In various embodiments, the software platform may store the source code and the transformed code in a data store. The transformed code is a transformation of the source code by at least one business semantic preserving code transform. The at least one business semantic preserving transform causes an execution of the transformed code in a new execution scenario to produce an identical semantic effect as an execution of the source code in an old execution scenario. Subsequently, the software platform may cause a display of a user interface of the application on a display device. The user interface may provide one or more user command items for manipulating at least one of the source code or the transformed code stored in the data store.

Abstract: Techniques to perform code separation with semantic guarantees are described. When porting a software application to a different target architecture and potentially to a different set of platforms and programming languages, application functionality will change based at least to accommodate architectural differences. However, business logic should be guaranteed to be semantically preserved, efficiency optimized to the platform benefits and limitations. Code separation identifies candidate components, associates the candidate components with a component classification or type, and automates the determining of which of the candidate components are to be associated with various portions of the target architecture. Automated code separation may include various inference algorithms to determine which components are to be associated with a component type. Also described are various use cases for code separation.

Abstract: Techniques to automatically port applications to a mobile infrastructure using code separation with semantic guarantees are disclosed. Porting enterprise applications from to a target architecture another is effected via separating code into constituent layers of the target architecture. To preserve semantics, code transformations are enforced via an abstract syntax tree structure. The generated code may have various code wrappers and/or infrastructure elements so the ported application will operate in the target architecture. Various techniques are disclosed regarding specific code wrappers and/or infrastructure elements to address operating issues including, but not limited to, architectural issues, network latency, framework changes, regulatory issues.

Abstract: An isolated fusion protein. In one embodiment of the present invention, the isolated fusion protein includes a membrane-translocating peptide sequence of about 8 to about 50 residues comprising at least eight consecutive residues of SEQ ID NO: 1 (Ala-Ala-Val-Leu-Leu-Pro-Val-Leu-Leu-Ala-Ala-Pro), and an inhibitory I?B protein. Alternatively, the membrane-translocating sequence can have at least 9, 10, 11 or 12 twelve consecutive residues of SEQ ID NO: 1. The isolated infusion protein can be used to treat or prevent an immune response associated with an immune disorder or a disease or disorder related to apoptosis, such as cancer, in a host.

Abstract: The invention describes a membrane-translocating peptide sequence (MTS) which facilitates entry of polypeptides and proteins into cells. Also described is an isolated nucleotide sequence encoding the membrane-translocating peptide and a method of using this sequence to genetically engineer proteins with cell membrane permeability. The MTS, and the method of genetically engineering proteins with cell membrane permeability, are useful for polypeptide and protein delivery for human and veterinary applications such as vaccine delivery and cancer therapy.

Abstract: The present invention provides a method of treating cystic fibrosis in a human subject diagnosed with cystic fibrosis, comprising administering to the subject, in a pharmaceutically acceptable carrier, an effective amount of a fusion protein, comprising a cystic fibrosis transmembrane conductance regulator (CFTR) and a membrane translocation sequence (MST), whereby the fusion protein can be taken up by affected cells in the subject, thereby treating cystic fibrosis. The present invention also provides a fusion protein comprising a cystic fibrosis transmembrane conductance regulator and a membrane translocation sequence.

Abstract: The invention describes a membrane-translocating peptide sequence (MTS) which facilitates entry of polypeptides and proteins into cells. Also described is an isolated nucleotide sequence encoding the membrane-translocating peptide and a method of using this sequence to genetically engineer proteins with cell membrane permeability. The MTS, and the method of genetically engineering proteins with cell membrane permeability, are useful for polypeptide and protein delivery for human and veterinary applications such as vaccine delivery and cancer therapy.

Abstract: The invention describes a membrane-translocating peptide sequence (MTS) which facilitates entry of polypeptides and proteins into cells. Also described is an isolated nucleotide sequence encoding the membrane-translocating peptide and a method of using this sequence to genetically engineer proteins with cell membrane permeability. The MTS, and the method of genetically engineering proteins with cell membrane permeability, are useful for polypeptide and protein delivery for human and veterinary applications such as vaccine delivery and cancer therapy.

Abstract: The invention describes a membrane-translocating peptide sequence (MTS) which facilitates entry of polypeptides and proteins into cells. Also described is an isolated nucleotide sequence encoding the membrane-translocating peptide and a method of using this sequence to genetically engineer proteins with cell membrane permeability. The MTS, and the method of genetically engineering proteins with cell membrane permeability, are useful for polypeptide and protein delivery for human and veterinary applications such as vaccine delivery and cancer therapy.

Abstract: Withajardins A-D are new class of withanolides isolated from the leaves of Deprea orinocensis and characterized by having a bicyclic C-17.beta. system and hydroxyl group at C-14 and C-17. The bicyclic system consists of a lactone and a homocyclic ring with six carbon atoms unlike the acnistins which have a five-membered homocyclic ring. The two classes of compounds were differentiated and their structures were identified by a series of HMQC, HMBC and finally X-ray diffraction experiments. Withajardins and acnistins would seem to evolve along quite dissimilar biosynthetic pathways although both types of compound show a marked immunosupressive effect on in vitro cultures of human lymphocytes.