Abstract: An electroporation therapy apparatus method, and system is provided. The apparatus, system, and method comprise an electroporation generator (26). The electroporation generator (26) is configured to output an asymmetric balanced waveform to a medical device, and the asymmetric balanced waveform comprises a first positive phase and a first negative phase. The first positive phase comprises a first current and a first time and the first negative phase comprises a second current and a second time. The first current is greater than the second current and the second time is greater than the first time. The asymmetric balanced waveform is configured to irreversibly electroporate a target tissue.

Abstract: An electroporation therapy apparatus method, and system is provided. The apparatus, system, and method comprise an electroporation generator (26). The electroporation generator (26) is configured to output an asymmetric balanced waveform to a medical device, and the asymmetric balanced waveform comprises a first positive phase and a first negative phase. The first positive phase comprises a first current and a first time and the first negative phase comprises a second current and a second time. The first current is greater than the second current and the second time is greater than the first time. The asymmetric balanced waveform is configured to irreversibly electroporate a target tissue.

Abstract: Method of operating, catheter and catherization system for measuring electrical impedances in blood vessels, within a annular area around the catheter. The catheter contains excitation electrodes, between which the impedance is measured through a potential difference between measuring electrodes present between those electrodes.Around the catheter a pattern of electrical field lines is created, a so-called counter current field, by varying the amplitude of the currents it being provided that between the measuring electrodes no or hardly any current runs and that at a larger distance of the measuring electrodes the electrical field lines are mainly perpendicular to the longitudinal axis of the catheter. The average impedance of the area to be measured and that of the area outside this will be measured separately.