Patents by Inventor Maurizio Balestrino

Maurizio Balestrino has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Therapeutic application of (Boc)-creatine
    Patent number: 9700539
    Abstract: A creatine derivative, (Boc)2-creatine, is used as a medicament, in particular in a therapeutic antitumor treatment. I (Boc)2-creatine.
    Type: Grant
    Filed: December 23, 2014
    Date of Patent: July 11, 2017
    Assignee: UNIVERSITA' DEGLI STUDI DI GENOVA
    Inventors: Patrizia Garbati, Maurizio Balestrino, Enrico Adriano, Silvia Ravera, Enrico Millo, Gianluca Damonte, Annalisa Salis
  • THERAPEUTIC APPLICATION OF (BOC)2-CREATINE
    Publication number: 20170000757
    Abstract: A creatine derivative, (Boc)2-creatine, is used as a medicament, in particular in a therapeutic antitumor treatment. I (Boc)2-creatine.
    Type: Application
    Filed: December 23, 2014
    Publication date: January 5, 2017
    Inventors: Patrizia GARBATI, Maurizio BALESTRINO, Enrico ADRIANO, Silvia RAVERA, Enrico MILLO, Gianluca DAMONTE, Annalisa SALIS
  • A METHOD OF SYNTHESIZING CREATINE DERIVATIVES
    Publication number: 20150368192
    Abstract: A method of synthesizing (Boc)2-creatine derivatives of formula (III) which comprises a first step in which a sarcosine ester is reacted with a guanylating agent comprising two nitrogen atoms each protected with a t-butoxycarbonyl (t-Boc) group to form a (Boc)2-creatine ester, and a second step in which the (Boc)2-creatine ester is subjected basic hydrolysis to form (Boc)2-creatine of formula (III) is described. The (Boc)2-creatine so obtained can be used in methods of synthesizing creatine and phosphocreatine derivatives in which the free carboxyl group of the creatine is conjugated with a desired molecule.
    Type: Application
    Filed: November 18, 2013
    Publication date: December 24, 2015
    Inventors: Enrico Millo, Maurizio Balestrino, Gianluca Damonte, Patrizia Garbati, Enrico Adriano, Annalisa Salis