Patents by Inventor Maurizio Di Grigoli

Maurizio Di Grigoli has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11123287
    Abstract: The present invention concerns an orodispersible self-supporting film free from hydrocolloids comprising: a) a film-forming substance consisting of a maltodextrin in an amount comprised between 40 and 80% by weight; b) a plasticizer in an amount comprised between 15 and 55% by weight; e) a surfactant System in an amount comprised between 0.5 and 6% by weight; d) an active ingredient for food or therapeutic use in an amount between 0.05 and 30% by weight, characterised in that it contains a homopolymer or a copolymer of vinyl acetate in a quantity comprised between 2 and 10% by weight where the percentages are calculated on the total weight of said film.
    Type: Grant
    Filed: September 26, 2013
    Date of Patent: September 21, 2021
    Assignee: PHARMAFILM S.R.L.
    Inventors: Francesco Cilurzo, Maurizio Di Grigoli, Paola Minghetti, Stefania Pagani
  • Publication number: 20210253291
    Abstract: The present invention concerns an orodispersible self-supporting film free from hydrocolloids comprising: a) a film-forming substance consisting of a maltodextrin in an amount comprised between 40 and 80% by weight; b) one or more plasticizer in a total amount comprised between 15 and 55% by weight; c) a surfactant System in an amount comprised between 0.5 and 6% by weight; d) an active ingredient for food or therapeutic use in an amount between 0.05 and 30% by weight, said orodispersible self-supporting film free from hydrocolloids further containing a homopolymer or a copolymer of vinyl acetate in a quantity comprised between 1 and 20% by weight where the percentages are calculated on the total weight of said film.
    Type: Application
    Filed: April 23, 2021
    Publication date: August 19, 2021
    Applicant: Pharmafilm S.r.l.
    Inventors: Francesco Cilurzo, Maurizio Di Grigoli, Paola Minghetti, Stefania Pagani
  • Patent number: 10328034
    Abstract: Polymeric matrices for the controlled release of medicaments for the topical transdermal use comprising copolymers of acrylic and/or methacrylic acid or esters thereof having a Tg lower than 0° C., whose free carboxy groups are salified with compatible organic or inorganic bases. The matrices of the invention allow to prepare therapeutical systems for the controlled-release of active principles through the transdermal route, thus solving stability, solubility and/or bioavailability problems of the active ingredient within the matrix.
    Type: Grant
    Filed: January 25, 2017
    Date of Patent: June 25, 2019
    Assignee: BOUTY S.P.A.
    Inventors: Paola Stefanelli, Alberto Scarsetto, Maurizio Di Grigoli, Pierbruno Romelli
  • Publication number: 20170143623
    Abstract: The present invention concerns an orodispersible self-supporting film free from hydrocolloids comprising: a) a film-forming substance consisting of a maltodextrin in an amount comprised between 40 and 80% by weight; b) one or more plasticizer in a total amount comprised between 15 and 55% by weight; e) a surfactant System in an amount comprised between 0.5 and 6% by weight; d) an active ingredient for food or therapeutic use in an amount between 0.05 and 30% by weight, said orodispersible self-supporting film free from hydrocolloids further containing a homopolymer or a copolymer of vinyl acetate in a quantity comprised between 1 and 20% by weight where the percentages are calculated on the total weight of said film.
    Type: Application
    Filed: February 3, 2017
    Publication date: May 25, 2017
    Inventors: Francesco Cilurzo, Maurizio Di Grigoli, Paola Minghetti, Stefania Pagani
  • Publication number: 20170128383
    Abstract: Polymeric matrices for the controlled release of medicaments for the topical transdermal use comprising copolymers of acrylic and/or methacrylic acid or esters thereof having a Tg lower than 0° C., whose free carboxy groups are salified with compatible organic or inorganic bases. The matrices of the invention allow to prepare therapeutical systems for the controlled-release of active principles through the transdermal route, thus solving stability, solubility and/or bioavailability problems of the active ingredient within the matrix.
    Type: Application
    Filed: January 25, 2017
    Publication date: May 11, 2017
    Applicant: BOUTY S.P.A.
    Inventors: Paola Stefanelli, Alberto Scarsetto, Maurizio Di Grigoli, Pierbruno Romelli
  • Patent number: 9119895
    Abstract: Disclosed is a self-adhesive matrix system comprising a styrene-ethylene/butylene-styrene (SEBS) copolymer in an oil/ethyl acetate mixture, a hydrogenated resin and a pharmaceutical or cosmetic active ingredient.
    Type: Grant
    Filed: December 10, 2009
    Date of Patent: September 1, 2015
    Assignee: BOUTY S.P.A.
    Inventors: Stefania Pagani, Maurizio Di Grigoli, Sergio Comuzio
  • Publication number: 20150231065
    Abstract: The present invention concerns an orodispersible self-supporting film free from hydrocolloids comprising: a) a film-forming substance consisting of a maltodextrin in an amount comprised between 40 and 80% by weight; b) a plasticizer in an amount comprised between 15 and 55% by weight; e) a surfactant System in an amount comprised between 0.5 and 6% by weight; d) an active ingredient for food or therapeutic use in an amount between 0.
    Type: Application
    Filed: September 26, 2013
    Publication date: August 20, 2015
    Inventors: Francesco Cilurzo, Maurizio Di Grigoli, Paola Minghetti, Stefania Pagani
  • Publication number: 20150021222
    Abstract: A multilayer structure for the packaging of biomedical films, in particular oral films, is described, said multilayer structure comprising cold-adhesive laminates and at least partly non-adhesive supporting layers which are organized in a specific stratified structure. The film packaged therein is effectively isolated from the external environment and protected from accidental mechanical stresses; the packaging process is low-cost and particularly attentive to the delicate structural characteristics of biomedical films.
    Type: Application
    Filed: January 10, 2013
    Publication date: January 22, 2015
    Inventors: Maurizio Di Grigoli, Sergio Comuzio
  • Publication number: 20140080911
    Abstract: Polymeric matrices for the controlled release of medicaments for the topical transdermal use comprising copolymers of acrylic and/or methacrylic acid or esters thereof having a Tg lower than 0.degree. C., whose free carboxy groups are salified with compatible organic or inorganic bases. The matrices of the invention allow to prepare therapeutical systems for the controlled-release of active principles through the transdermal route, thus solving stability, solubility and/or bioavailability problems of the active ingredient within the matrix.
    Type: Application
    Filed: November 20, 2013
    Publication date: March 20, 2014
    Inventors: Paola Stefanelli, Alberto Scarsetto, Maurizio Di Grigoli, Pierbruno Romelli
  • Publication number: 20110243985
    Abstract: Disclosed is a self-adhesive matrix system comprising a styrene-ethylene/butylene-styrene (SEBS) copolymer in an oil/ethyl acetate mixture, a hydrogenated resin and a pharmaceutical or cosmetic active ingredient.
    Type: Application
    Filed: December 10, 2009
    Publication date: October 6, 2011
    Inventors: Stefania Pagani, Maurizio Di Grigoli, Sergio Comuzio
  • Publication number: 20080292708
    Abstract: Polymeric matrices for the controlled release of medicaments for the topical transdermal use comprising copolymers of acrylic and/or methacrylic acid or esters thereof having a Tg lower than 0° C., whose free carboxy groups are salified with compatible organic or inorganic bases. The matrices of the invention allow to prepare therapeutical systems for the controlled-release of active principles through the transdermal route, thus solving stability, solubility and/or bioavailability problems of the active ingredient within the matrix.
    Type: Application
    Filed: July 6, 2005
    Publication date: November 27, 2008
    Inventors: Paola Stefanelli, Alberto Scarsetto, Maurizio Di Grigoli, Pierbruno Romelli