Abstract: Device planned to inform, by telephonic vocal messages, the danger of decay of medicines and foodstuffs or, in general, perishable goods preserved in refrigerating units in pharmacies, drug-stores, supermarkets and similar, giving an information about the condition of the refrigerator. Device that includes one or more sensors, even cordless, connected to a circuit that includes a microcontroller with a software application that manages, jointly to the peripherals included into the circuit: the measurement and the control of temperatures; the remote and local signalling of alarm; the warning about the loss or return of energy; the vision, on the display, of the temperatures and working's values; the remote enquiry and programming.

Abstract: The present invention provides a method of screening test compounds and test conditions for the ability to modulate (activate or inhibit, enhance or depress) a GPCR pathway, and provides methods of assessing GPCR pathway function, such as the function of an orphan GPCR, in a cell in general. In another aspect of the present method, lipophilic photosensitizers are attached to the cellular membranes. A candidate ligand or a library of candidate ligands can be attached to a molecular, after which the ligand is allowed to bind to the receptor. After excitation of the photosensitizer with a light source, the cleavable linker is cleaved releasing the molecular tag. The released molecular tag can be detected in the extracellular fluid, as detailed above, which provides information on the structure of the ligand for the GPCR.