Patents by Inventor Maurizio Ricotti

Maurizio Ricotti has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10717715
    Abstract: Disclosed are solid forms of ingenol 3-(3,5-diethylisoxazole-4-carboxylate) selected from an amorphous form or a crystalline anhydrous form. Also disclosed are solid solvates of ingenol 3-(3,5-diethylisoxazole-4-carboxylate) selected from an acetone solvate, a dimethylcarbonate solvate, an isopropyl ether solvate, an acetonitrile solvate, a toluene solvate, a mesitylene solvate, a nitromethane solvate, a dichloromethane/heptane solvate and an ethyl acetate solvate, for use as intermediates.
    Type: Grant
    Filed: August 29, 2017
    Date of Patent: July 21, 2020
    Assignee: INDENA S.P.A.
    Inventors: Pietro Allegrini, Federico Peterlongo, Andrea Gambini, Daniele Ciceri, Nicola Sardone, Maurizio Ricotti
  • Publication number: 20190210980
    Abstract: Disclosed are solid forms of ingenol 3-(3,5-diethylisoxazole-4-carboxylate) selected from an amorphous form or a crystalline anhydrous form. Also disclosed are solid solvates of ingenol 3-(3,5-diethylisoxazole-4-carboxylate) selected from an acetone solvate, a dimethylcarbonate solvate, an isopropyl ether solvate, an acetonitrile solvate, a toluene solvate, a mesitylene solvate, a nitromethane solvate, a dichloromethane/heptane solvate and an ethyl acetate solvate, for use as intermediates.
    Type: Application
    Filed: August 29, 2017
    Publication date: July 11, 2019
    Inventors: Pietro ALLEGRINI, Federico PETERLONGO, Andrea GAMBINI, Daniele CICERI, Nicola SARDONE, Maurizio RICOTTI
  • Patent number: 9127018
    Abstract: The present invention relates to solid forms of 13-(N-Boc-?-isobutylserinyl)-14-? hydroxybaccatin III 1, 14-carbonate (Ortataxel). Amorphous Form A, crystalline Form B, mixtures thereof and processes for preparing them are disclosed. Amorphous Form A is prepared by fast precipitation of Ortataxel from a mixture of acetone and water. Form A transforms in Form B when suspended and stirred in a mixture of ethanol and water for 4-8 hours. If the suspension is stirred for less than 4 hours, mixtures of Form B and Form A are obtained. Form B or mixtures of Forms A and B can also be obtained dissolving Ortataxel in a protic organic solvent, followed by addition of water.
    Type: Grant
    Filed: December 10, 2013
    Date of Patent: September 8, 2015
    Assignee: Indena S.p.A.
    Inventors: Daniele Ciceri, Nicola Sardone, Bruno Gabetta, Maurizio Ricotti
  • Patent number: 9062018
    Abstract: A crystalline from of 13-[(N-tert-butoxycarbonyl)-2?-O-hexanoyl-3-phenylisoserinyl]-10-deacetylbaccatin III.
    Type: Grant
    Filed: October 27, 2011
    Date of Patent: June 23, 2015
    Assignee: Indena S.p.A
    Inventors: Daniele Ciceri, Andrea Gambini, Maurizio Ricotti, Nicola Sardone
  • Publication number: 20140303240
    Abstract: A crystalline from of 13[(N-tert-butoxycarbonyl)-2?-O-hexanoyl-3-phenylisoserinyl]-10-deacetylbaccatin III.
    Type: Application
    Filed: October 27, 2011
    Publication date: October 9, 2014
    Applicant: Indena S.p.A.
    Inventors: Daniele Ciceri, Andrea Gambini, Maurizio Ricotti, Nicola Sardone
  • Publication number: 20140128459
    Abstract: The present invention relates to solid forms of 13-(N-Boc-?-isobutylserinyl)-14-?hydroxybaccatin III 1, 14-carbonate (Ortataxel). Amorphous Form A, crystalline Form B, mixtures thereof and processes for preparing them are disclosed. Amorphous Form A is prepared by fast precipitation of Ortataxel from a mixture of acetone and water. Form A transforms in Form B when suspended and stirred in a mixture of ethanol and water for 4-8 hours. If the suspension is stirred for less than 4 hours, mixtures of Form B and Form A are obtained. Form B or mixtures of Forms A and B can also be obtained dissolving Ortataxel in a protic organic solvent, followed by addition of water.
    Type: Application
    Filed: December 10, 2013
    Publication date: May 8, 2014
    Applicant: Indena S.p.A.
    Inventors: Daniele Ciceri, Nicola Sardone, Bruno Gabetta, Maurizio Ricotti
  • Publication number: 20110054015
    Abstract: The present invention relates to solid forms of 13-(N-Boc-?-isobutylserinyl)-14-?-hydroxybaccatin III 1,14-carbonate (Ortataxel). Amorphous Form A, crystalline Form B, mixtures thereof and processes for preparing them are disclosed. Amorphous Form A is prepared by fast precipitation of Ortataxel from a mixture of acetone and water. Form A transforms in Form B when suspended and stirred in a mixture of ethanol and water for 4-8 hours. If the suspension is stirred for less than 4 hours, mixtures of Form B and Form A are obtained. Form B or mixtures of Forms A and B can also be obtained dissolving Ortataxel in a protic organic solvent, followed by addition of water.
    Type: Application
    Filed: January 12, 2009
    Publication date: March 3, 2011
    Applicant: Indena S.p.A.
    Inventors: Daniele Ciceri, Nicola Sardone, Bruno Gabetta, Maurizio Ricotti