Patents by Inventor Maurizio TADDEI

Maurizio TADDEI has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for Producing Aliskiren
    Publication number: 20130071899
    Abstract: A new route of synthesis of the compound Aliskiren of formula (I), used in the treatment of hypertension, is described.
    Type: Application
    Filed: June 3, 2011
    Publication date: March 21, 2013
    Applicant: Chemo Iberica, S.A.
    Inventors: Maurizio Taddei, Adele Russo, Elena Cini, Renata Riva, Marcello Rasparini, Luca Carcone, Luca Banfi, Romina Vitale, Stephen Roseblade, Antonio Carlo Zanotti-Gerosa
  • Acyl Guanidine Derivatives Modulating The Hedgehog Protein Signaling Pathway
    Publication number: 20120196865
    Abstract: The present invention relates to acyl guanidine derivatives modulating the hedgehog protein signaling pathway to be used as drugs, in particular for treating diseases involving a tissue dysfunction associated with a deregulation of the hedgehog protein signaling pathway, as well as to pharmaceutical compositions containing same. The present invention also relates to novel acyl guanidine derivatives as such.
    Type: Application
    Filed: July 19, 2010
    Publication date: August 2, 2012
    Applicants: UNIVERSITE DE STRASBOURG, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
    Inventors: Martial Ruat, Hélène Faure, Elisabeth Traiffort, Hermine Roudaut, André Mann, Angèle Schoenfelder, Maurizio Taddei, Fabrizio Manetti, Antonio Solinas
  • N-Acylthiourea and N-Acylurea Inhibitors of the Hedgehog Protein Signalling Pathway
    Publication number: 20110275663
    Abstract: The present invention relates to the use of acylthiourea or acylurea derivatives for the treatment of pathologies involving a tissue dysfunction associated with a deregulation of the Hedgehog protein signalling pathway, and also to novel acylthiourea or acylurea derivatives as such, to their use as a medicinal product, and to pharmaceutical compositions containing them.
    Type: Application
    Filed: April 16, 2009
    Publication date: November 10, 2011
    Inventors: Martial Ruat, Hélène Faure, Elisabeth Traiffort, Angèle Schoenfelder, André Mann, Maurizio Taddei, Antonio Solinas, Fabrizio Manetti
  • PROCESS FOR PREPARING STATINS
    Publication number: 20110269962
    Abstract: Process for the preparation of ?-ketoester synthetic intermediates useful in the preparation of statins, in particular Pitavastatin.
    Type: Application
    Filed: April 22, 2011
    Publication date: November 3, 2011
    Applicant: DIPHARMA FRANCIS S.R.L.
    Inventors: Maurizio TADDEI, Evita BALDUCCI, Emanuele ATTOLINO, Simone MANTEGAZZA, Gianmaria DELL'ANNA
  • Process for the Preparation of Bosentan
    Publication number: 20090156811
    Abstract: A process for the preparation of 4-tert-butyl-N-[6-(2-hydroxy-ethoxy)-5-(2-methoxy-phenoxy)-[2,2?]bipyrimidinyl-4-yl]-benzenesulfonamide, bosentan, comprising the reaction of a compound of formula (II) or a salt thereof, wherein Z is an optionally protected hydroxy group, with a compound of formula (III), in the presence of a base; and, if necessary, the removal of the hydroxy-protecting group, and/or, if desired, the conversion of a compound of formula (I) to a salt thereof, or vice versa; and novel intermediates useful for its synthesis.
    Type: Application
    Filed: December 11, 2008
    Publication date: June 18, 2009
    Applicant: Dipharma Francis S.r.l.
    Inventors: Maurizio TADDEI, Diletta Naldini, Pietro Allegrini, Gabriele Razzetti, Simone Mantegazza