Patents by Inventor Mauro Ajani

Mauro Ajani has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20140154306
    Abstract: 17?,21-Dihydroxypregna-4,9-diene-3,20-dione and 17?,21-dihydroxypregna-4-ene-3,20-dione 17 and/or 21 esters of having remarkable antiandrogenic activity, and the processes for the preparation thereof.
    Type: Application
    Filed: December 11, 2013
    Publication date: June 5, 2014
    Applicant: COSMO S.P.A.
    Inventors: Mauro AJANI, Luigi MORO
  • Patent number: 8741948
    Abstract: The present invention relates to oral pharmaceutical compositions with controlled and/or programmed release containing at least one active ingredient having antimicrobial and/or anti-infectious activity for the treatment of infections of the large intestine, in particular the colon.
    Type: Grant
    Filed: August 22, 2012
    Date of Patent: June 3, 2014
    Assignee: Cosmo Technologies Ltd.
    Inventors: Mauro Ajani, Roberta Bozzella, Giuseppe Celasco, Roberto Villa
  • Publication number: 20140127292
    Abstract: Oral pharmaceutical compositions for the controlled release of heparin or derivatives thereof, for example dalteparin, salts and/or derivatives thereof, comprising (a) a matrix consisting of amphiphilic compounds and lipophilic compounds with melting point lower than 90° C. in which the active ingredient is at least partially dispersed; (b) an outer hydrophilic matrix in which the lipophilic/amphiphilic matrix is dispersed; (c) optionally, other excipients suitable for solid pharmaceutical forms. The treatment of inflammatory bowel diseases (IBD) by administering to a patient in need thereof an effective amount of dalteparin, salts and/or derivatives thereof is also disclosed.
    Type: Application
    Filed: December 30, 2013
    Publication date: May 8, 2014
    Applicant: Cosmo Technologies Limited
    Inventors: Mauro Ajani, Luigi Moro, Roberto Villa
  • Patent number: 8642082
    Abstract: Pharmaceutical compositions suitable for the oral administration of heparin or derivatives thereof, particularly controlled-release oral pharmaceutical compositions containing heparin with different molecular weight, for the treatment of inflammatory bowel diseases and related conditions, are disclosed.
    Type: Grant
    Filed: December 3, 2002
    Date of Patent: February 4, 2014
    Assignee: Cosmo Technologies Limited
    Inventors: Mauro Ajani, Luigi Moro, Roberto Villa
  • Patent number: 8529945
    Abstract: The present invention relates to oral pharmaceutical compositions with controlled and/or programmed release containing at least one active ingredient having antimicrobial and/or anti-infectious activity for the treatment of infections of the large intestine, in particular the colon.
    Type: Grant
    Filed: September 14, 2012
    Date of Patent: September 10, 2013
    Assignee: Cosmo Technologies Ltd.
    Inventors: Mauro Ajani, Roberta Bozzella, Giuseppe Celasco, Roberto Villa
  • Patent number: 8486446
    Abstract: The present invention relates to oral pharmaceutical compositions with controlled and/or programmed release containing at least one active ingredient having antimicrobial and/or anti-infectious activity for the treatment of infections of the large intestine, in particular the colon.
    Type: Grant
    Filed: May 3, 2005
    Date of Patent: July 16, 2013
    Assignee: Cosmo Technologies Ltd.
    Inventors: Mauro Ajani, Roberta Bozzella, Giuseppe Celasco, Roberto Villa
  • Publication number: 20130022679
    Abstract: Controlled release and taste masking compositions containing one or more active principles inglobated in a three-component matrix structure, i.e. a structure formed by successive amphiphilic, lipophilic or inert matrices and finally inglobated or dispersed in hydrophilic matrices. The use of a plurality of systems for the control of the dissolution of the active ingredient modulates the dissolution rate of the active ingredient in aqueous and/or biological fluids, thereby controlling the release kinetics in the gastrointestinal tract.
    Type: Application
    Filed: September 14, 2012
    Publication date: January 24, 2013
    Applicant: COSMO TECHNOLOGIES LIMITED
    Inventors: Roberto VILLA, Massimo PEDRANI, Mauro AJANI, Lorenzo FOSSATI
  • Publication number: 20130004569
    Abstract: The present invention relates to oral pharmaceutical compositions with controlled and/or programmed release containing at least one active ingredient having antimicrobial and/or anti-infectious activity for the treatment of infections of the large intestine, in particular the colon.
    Type: Application
    Filed: September 14, 2012
    Publication date: January 3, 2013
    Applicant: COSMO TECHNOLOGIES LIMITED
    Inventors: Mauro AJANI, Roberta BOZZELLA, Giuseppe CELASCO, Roberto VILLA
  • Publication number: 20120321710
    Abstract: Controlled release and taste masking compositions containing one or more active principles inglobated in a three-component matrix structure, i.e. a structure formed by successive amphiphilic, lipophilic or inert matrices and finally inglobated or dispersed in hydrophilic matrices. The use of a plurality of systems for the control of the dissolution of the active ingredient modulates the dissolution rate of the active ingredient in aqueous and/or biological fluids, thereby controlling the release kinetics in the gastrointestinal tract.
    Type: Application
    Filed: August 29, 2012
    Publication date: December 20, 2012
    Applicant: COSMO TECHNOLOGIES LIMITED
    Inventors: Roberto VILLA, Massimo PEDRANI, Mauro AJANI, Lorenzo FOSSATI
  • Publication number: 20120316228
    Abstract: The present invention relates to oral pharmaceutical compositions with controlled and/or programmed release containing at least one active ingredient having antimicrobial and/or anti-infectious activity for the treatment of infections of the large intestine, in particular the colon.
    Type: Application
    Filed: August 22, 2012
    Publication date: December 13, 2012
    Applicant: COSMO TECHNOLOGIES LIMITED
    Inventors: Mauro AJANI, Roberta BOZZELLA, Giuseppe CELASCO, Roberto VILLA
  • Publication number: 20120316229
    Abstract: The present invention relates to oral pharmaceutical compositions with controlled and/or programmed release containing at least one active ingredient having antimicrobial and/or anti-infectious activity for the treatment of infections of the large intestine, in particular the colon.
    Type: Application
    Filed: August 22, 2012
    Publication date: December 13, 2012
    Applicant: COSMO TECHNOLOGIES LIMITED
    Inventors: Mauro AJANI, Roberta BOZZELLA, Giuseppe CELASCO, Roberto VILLA
  • Publication number: 20120309959
    Abstract: Controlled release and taste masking compositions containing one or more active principles inglobated in a three-component matrix structure, i.e. a structure formed by successive amphiphilic, lipophilic or inert matrices and finally inglobated or dispersed in hydrophilic matrices. The use of a plurality of systems for the control of the dissolution of the active ingredient modulates the dissolution rate of the active ingredient in aqueous and/or biological fluids, thereby controlling the release kinetics in the gastrointestinal tract.
    Type: Application
    Filed: August 14, 2012
    Publication date: December 6, 2012
    Applicant: COSMO TECHNOLOGIES LIMITED
    Inventors: Roberto VILLA, Massimo PEDRANI, Mauro AJANI, Lorenzo FOSSATI
  • Patent number: 8293273
    Abstract: Controlled release and taste masking compositions containing one or more active principles inglobated in a three-component matrix structure, i.e. a structure formed by successive amphiphilic, lipophilic or inert matrices and finally inglobated or dispersed in hydrophilic matrices. The use of a plurality of systems for the control of the dissolution of the active ingredient modulates the dissolution rate of the active ingredient in aqueous and/or biological fluids, thereby controlling the release kinetics in the gastrointestinal tract.
    Type: Grant
    Filed: May 2, 2012
    Date of Patent: October 23, 2012
    Assignee: Cosmo Technologies Limited
    Inventors: Roberto Villa, Massimo Pedrani, Mauro Ajani, Lorenzo Fossati
  • Patent number: 8263120
    Abstract: The present invention relates to oral pharmaceutical compositions with controlled and/or programmed release containing at least one active ingredient having antimicrobial and/or anti-infectious activity for the treatment of infections of the large intestine, in particular the colon.
    Type: Grant
    Filed: April 19, 2012
    Date of Patent: September 11, 2012
    Assignee: Cosmo Technologies Ltd.
    Inventors: Mauro Ajani, Roberta Bozzella, Giuseppe Celasco, Roberto Villa
  • Publication number: 20120220559
    Abstract: Controlled release and taste masking compositions containing one or more active principles inglobated in a three-component matrix structure, i.e. a structure formed by successive amphiphilic, lipophilic or inert matrices and finally inglobated or dispersed in hydrophilic matrices. The use of a plurality of systems for the control of the dissolution of the active ingredient modulates the dissolution rate of the active ingredient in aqueous and/or biological fluids, thereby controlling the release kinetics in the gastrointestinal tract.
    Type: Application
    Filed: May 2, 2012
    Publication date: August 30, 2012
    Applicant: COSMO TECHNOLOGIES LIMITED
    Inventors: Roberto VILLA, Massimo PEDRANI, Mauro AJANI, Lorenzo FOSSATI
  • Publication number: 20120213850
    Abstract: Controlled release and taste masking compositions containing one or more active principles inglobated in a three-component matrix structure, i.e. a structure formed by successive amphiphilic, lipophilic or inert matrices and finally inglobated or dispersed in hydrophilic matrices. The use of a plurality of systems for the control of the dissolution of the active ingredient modulates the dissolution rate of the active ingredient in aqueous and/or biological fluids, thereby controlling the release kinetics in the gastrointestinal tract.
    Type: Application
    Filed: May 2, 2012
    Publication date: August 23, 2012
    Applicant: COSMO TECHNOLOGIES LIMITED
    Inventors: Roberto VILLA, Massimo PEDRANI, Mauro AJANI, Lorenzo FOSSATI
  • Publication number: 20120207834
    Abstract: The present invention relates to oral pharmaceutical compositions with controlled and/or programmed release containing at least one active ingredient having antimicrobial and/or anti-infectious activity for the treatment of infections of the large intestine, in particular the colon.
    Type: Application
    Filed: April 19, 2012
    Publication date: August 16, 2012
    Applicant: COSMO TECHNOLOGIES LIMITED
    Inventors: Mauro AJANI, Roberta BOZZELLA, Giuseppe CELASCO, Roberto VILLA
  • Publication number: 20120149671
    Abstract: 17?,21-Dihydroxypregna-4,9-diene-3,20-dione and 17?,21-dihydroxypregna-4-ene-3.20-dione 17 and/or 21 esters of having remarkable antiandrogenic activity, and the processes for the preparation thereof.
    Type: Application
    Filed: February 16, 2012
    Publication date: June 14, 2012
    Applicant: COSMO SPA,
    Inventors: Mauro Ajani, Luigi Moro
  • Patent number: 8143240
    Abstract: 17?,21-Dihydroxypregna-4,9-diene-3,20-dione and 17?,21-dihydroxypregna-4-ene-3,20-dione 17 and/or 21 esters of having remarkable antiandrogenic activity, and the processes for the preparation thereof.
    Type: Grant
    Filed: June 24, 2009
    Date of Patent: March 27, 2012
    Assignee: Cosmo S.p.A.
    Inventors: Mauro Ajani, Luigi Moro
  • Patent number: RE43799
    Abstract: Controlled release and taste masking compositions containing one or more active principles inglobated in a three-component matrix structure, i.e. a structure formed by successive amphiphilic, lipophilic or inert matrices and finally inglobated or dispersed in hydrophilic matrices. The use of a plurality of systems for the control of the dissolution of the active ingredient modulates the dissolution rate of the active ingredient in aqueous and/or biological fluids, thereby controlling the release kinetics in the gastrointestinal tract.
    Type: Grant
    Filed: May 22, 2012
    Date of Patent: November 13, 2012
    Assignee: Cosmo Technologies Limited
    Inventors: Roberto Villa, Massimo Pedrani, Mauro Ajani, Lorenzo Fossati