Patents by Inventor Mauro P. Avanzi

Mauro P. Avanzi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMPOSITIONS AND METHODS FOR IMMUNOTHERAPY
    Publication number: 20190151363
    Abstract: The present disclosure provides methods and compositions for enhancing the immune response toward cancers and pathogens. It relates to immunoresponsive cells comprising antigen recognizing receptors (e.g., chimeric antigen receptors (CARs) or T cell receptors (TCRs)), and expressing increased level of IL-18. In certain embodiments, the engineered immunoresponsive cells are antigen-directed and resistant to immunosuppression and/or have enhanced immune-activating properties.
    Type: Application
    Filed: February 1, 2019
    Publication date: May 23, 2019
    Applicant: MEMORIAL SLOAN-KETTERING CANCER CENTER
    Inventors: Renier J. Brentjens, Mauro P. Avanzi, Sarah Yoo
  • MEGAKARYOCYTE AND PLATELET PRODUCTION FROM STEM CELLS
    Publication number: 20170121682
    Abstract: Methods for obtaining purified populations of megakaryocytes and platelets by ex vivo culture of stem cells are provided herein.
    Type: Application
    Filed: January 9, 2017
    Publication date: May 4, 2017
    Inventors: W. Beau Mitchell, Mauro P. Avanzi
  • Megakaryocyte and platelet production from stem cells
    Patent number: 9574178
    Abstract: Methods for obtaining purified populations of megakaryocytes and platelets by ex vivo culture of stem cells are provided herein.
    Type: Grant
    Filed: March 16, 2012
    Date of Patent: February 21, 2017
    Assignee: New York Blood Center, Inc.
    Inventors: W. Beau Mitchell, Mauro P. Avanzi
  • Megakaryocyte and Platelet Production from Stem Cells
    Publication number: 20120238020
    Abstract: Methods for obtaining purified populations of megakaryocytes and platelets by ex vivo culture of stem cells are provided herein.
    Type: Application
    Filed: March 16, 2012
    Publication date: September 20, 2012
    Inventors: W. Beau Mitchell, Mauro P. Avanzi