Patents by Inventor Mauro Papagni

Mauro Papagni has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Stabilization of the enzyme urate oxidase in liquid form
    Patent number: 5266472
    Abstract: This invention relates to a process for stabilizing the enzyme urate oxidase (commonly known as uricase) in liquid form, and to the relative compositions which can then be obtained, with particular reference to compositions containing a Trinder reagent. According to the process of the invention, uricase can be stabilized in liquid form by adding to the composition containing the enzyme a substituted or unsubstituted dicarboxylic acid containing from 2 to 5 carbon atoms, and preferably 4 or 5. Aspartic acid has shown to be particularly effective in providing said stabilizing activity in liquid uricase compositions containing a Trinder reagent.
    Type: Grant
    Filed: May 7, 1992
    Date of Patent: November 30, 1993
    Assignee: Instrumentation Laboratory S.R.L.
    Inventors: Maurizio D'Alterio, Dario Frontini, Mauro Papagni