Patents by Inventor Mauro Sergio Sandrin

Mauro Sergio Sandrin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Nucleic acids encoding a chimeric glycosyltransferase
    Patent number: 7001998
    Abstract: The invention relates to nucleic acids which encode glycosyltransferase and are useful in producing cells and organs from one species which may be used for transplantation into a recipient of another species. It also relates to the production of nucleic acids which, when present in cells of a transplanted organ, result in reduced levels of antibody recognition of the transplanted organ.
    Type: Grant
    Filed: August 1, 1997
    Date of Patent: February 21, 2006
    Assignee: The Austin Research Institute
    Inventors: Ian Farquhar Campbell McKenzie, Mauro Sergio Sandrin
  • Targeting hydrolase enzymes
    Publication number: 20020081654
    Abstract: A nucleic acid construct encoding a peptide with hydrolase activity and a heterologous localization signal which locates the peptide, upon expression of the construct in a cell, to a cellular location proximal to the cellular site of a glycosylated agent or a glycosylating agent. The construct can be used to produce, for example, organs suitable for transplantation which show reduced levels of the epitope Gal&agr;(1,3)Gal.
    Type: Application
    Filed: April 6, 2001
    Publication date: June 27, 2002
    Inventors: Mauro Sergio Sandrin, Ian Farquhar Campbell McKenzie, Narin Osman
  • Nucleic acids for reducing carbohydrate epitopes
    Patent number: 6399758
    Abstract: The invention provides nucleic acids that encode a first glycosyltransferase that competes with a second enzyme for a substrate, thereby reducing the formation of a product of the second enzyme. The nucleic acids are useful in producing cells and organs with reduced antigenicity and which may be used for transplantation.
    Type: Grant
    Filed: June 11, 1999
    Date of Patent: June 4, 2002
    Assignee: The Austin Research Institute
    Inventors: Mauro Sergio Sandrin, Ian Campbell Farquhar McKenzie
  • NUCLEIC ACIDS FOR REDUCING CARBOHYDRATE EPITOPES
    Publication number: 20020031494
    Abstract: The invention relates to nucleic acids which encode a first glycosyltransferase which competes with a second enzyme for a substrate, thereby reducing the formation of a product of the second enzyme. The nucleic acids are useful in producing cells and organs with reduced antigenicity and which may be used for transplantation.
    Type: Application
    Filed: June 11, 1999
    Publication date: March 14, 2002
    Inventors: MAURO SERGIO SANDRIN, IAN CAMPBELL FARQUHAR MCKENZIE
  • Mimicking peptides in cancer therapy
    Patent number: 6344203
    Abstract: Peptide mimicks of MUC1 or other cancer peptides which can be included in cancer vaccines and used in therapeutic methods for the treatment of cancer patients.
    Type: Grant
    Filed: June 23, 1998
    Date of Patent: February 5, 2002
    Assignee: The Austin Research Institute
    Inventors: Mauro Sergio Sandrin, Ian Farquar Campbell McKenzie, Vasso Apostolopoulos
  • IMPROVED NUCLEIC ACIDS ENCODING A CHIMERIC GLYCOSYLTRANSFERASE
    Publication number: 20010055584
    Abstract: The invention relates to nucleic acids which encode glycosyltransferase and are useful in producing cells and organs from one species which may be used for transplantation into a recipient of another species. It also relates to the production of nucleic acids which, when present in cells of a transplanted organ, result in reduced levels of antibody recognition of the transplanted organ.
    Type: Application
    Filed: March 31, 1998
    Publication date: December 27, 2001
    Inventors: IAN FARQUHAR CAMPBELL MCKENZIE, MAURO SERGIO SANDRIN