Abstract: This disclosure provides dimeric, pentameric, and hexameric Tumor Necrosis Factor (TNF) superfamily receptor protein binding molecules and methods of using such binding molecules to direct apoptosis-mediated killing of TNF receptor-expressing cells.

Abstract: This disclosure provides dimeric, pentameric, and hexameric Tumor Necrosis Factor (TNF) superfamily receptor protein binding molecules and methods of using such binding molecules to direct apoptosis-mediated killing of TNF receptor-expressing cells.

Abstract: Techniques for implementing a system including a pipe segment and a test head. The test head includes a shell that defines an annulus cavity to be used to interface with an annulus of the pipe segment, in which the shell includes a bore insert having a male taper to be inserted into a pipe bore of the pipe segment, a testing port that extends through the shell and fluidly coupled to the annulus cavity, and an internal clamp assembly including clamp segments having a female taper that slidably interface with the male taper of the bore insert, in which an outer surface diameter of the clamp segments is controlled by position of the clamp segments on the bore insert to facilitate selectively securing and sealing an open end of the pipe segment in the test head to enable integrity of the tubing to be tested.

Abstract: Techniques for implementing a system including a pipe segment and a test head. The test head includes a shell that defines an annulus cavity to be used to interface with an annulus of the pipe segment, in which the shell includes a bore insert having a male taper to be inserted into a pipe bore of the pipe segment, a testing port that extends through the shell and fluidly coupled to the annulus cavity, and an internal clamp assembly including clamp segments having a female taper that slidably interface with the male taper of the bore insert, in which an outer surface diameter of the clamp segments is controlled by position of the clamp segments on the bore insert to facilitate selectively securing and sealing an open end of the pipe segment in the test head to enable integrity of the tubing to be tested.

Abstract: A pipe handling device and method for use with a horizontal directional drilling system. The pipe handling device stores sections of drill pipe in individual columns within a magazine. The magazine is constructed so that it can be mounted to a boring machine in a pin-up or pin-down orientation. A plurality of signal elements are attached to the magazine and each extend at least partially within a footprint of each column. The signal elements may move from a first position, indicating the column is full of pipe sections, to a second position, indicating the column is not full of pipe sections. A proximity sensor assembly detects movement of the individual signal elements and signals a processor accordingly. These signals indicate whether or not a given column is full of pipe sections.

Abstract: This disclosure provides dimeric, pentameric, and hexameric Tumor Necrosis Factor (TNF) superfamily receptor protein binding molecules and methods of using such binding molecules to direct apoptosis-mediated killing of TNF receptor-expressing cells.

Abstract: A pipe handling device and method for use with a horizontal directional drilling system. The pipe handling device stores sections of drill pipe in individual columns within a magazine. The magazine is constructed so that it can be mounted to a boring machine in a pin-up or pin-down orientation. A plurality of signal elements are attached to the magazine and each extend at least partially within a footprint of each column. The signal elements may move from a first position, indicating the column is full of pipe sections, to a second position, indicating the column is not full of pipe sections. A proximity sensor assembly detects movement of the individual signal elements and signals a processor accordingly. These signals indicate whether or not a given column is full of pipe sections.

Abstract: A pipe handling device and method for use with a horizontal directional drilling system. The pipe handling device stores sections of drill pipe in individual columns within a magazine. The magazine is constructed so that it can be mounted to a boring machine in a pin-up or pin-down orientation. A plurality of signal elements are attached to the magazine and each extend at least partially within a footprint of each column. The signal elements may move from a first position, indicating the column is full of pipe sections, to a second position, indicating the column is not full of pipe sections. A proximity sensor assembly detects movement of the individual signal elements and signals a processor accordingly. These signals indicate whether or not a given column is full of pipe sections.

Abstract: This disclosure provides dimeric, pentameric, and hexameric Tumor Necrosis Factor (TNF) superfamily receptor protein binding molecules and methods of using such binding molecules to direct apoptosis-mediated killing of TNF receptor-expressing cells.

Abstract: This disclosure provides dimeric, pentameric, and hexameric Tumor Necrosis Factor (TNF) superfamily receptor protein binding molecules and methods of using such binding molecules to direct apoptosis-mediated killing of TNF receptor-expressing cells.

Abstract: A pipe handling device and method for use with a horizontal directional drilling system. The pipe handling device stores sections of drill pipe in individual columns within a magazine. The magazine is constructed so that it can be mounted to a boring machine in a pin-up or pin-down orientation. A plurality of signal elements are attached to the magazine and each extend at least partially within a footprint of each column. The signal elements may move from a first position, indicating the column is full of pipe sections, to a second position, indicating the column is not full of pipe sections. A proximity sensor assembly detects movement of the individual signal elements and signals a processor accordingly. These signals indicate whether or not a given column is full of pipe sections.

Abstract: A spindle assembly for connecting a drill string to a rotational drive for use in a horizontal directional drilling operation. The assembly comprises a saver sub attached to the rotational drive, and a drive chuck for connection to the drill string. The drive chuck and saver sub form a torque-transmitting connection by engaging through a seat in the saver sub and an engagement point on the drive chuck. Dowel pins may be used to rotationally lock and provide the engagement between the saver sub and the drive chuck. A collar may thread to the saver sub and cause an interference fit by engaging the drive chuck at a shoulder.

Abstract: This invention relates to polymerizable ultraviolet light absorbers and yellow colorants and their use in ophthalmic lenses. In particular, this invention relates to polymerizable ultraviolet light absorbing methane compounds and yellow compounds of the methine and anthraquinone classes that block ultraviolet light and/or violet-blue light transmission through ophthalmic lenses.

Abstract: The present invention is directed to a spindle assembly for connecting a drill string to a rotational drive for use in a horizontal directional drilling operation. The assembly comprises a saver sub attached to the rotational drive, and a drive chuck for connection to the drill string. The drive chuck and saver sub form a torque-transmitting connection by engaging through a seat in the saver sub and an engagement point on the drive chuck. Dowel pins may be used to rotationally lock and provide the engagement between the saver sub and the drive chuck. A collar may thread to the saver sub and cause an interference fit by engaging the drive chuck at a shoulder.

Abstract: This invention relates to polymerizable ultraviolet light absorbers and yellow colorants and their use in ophthalmic lenses. In particular, this invention relates to polymerizable ultraviolet light absorbing methane compounds and yellow compounds of the methine and anthraquinone classes that block ultraviolet light and/or violet-blue light transmission through ophthalmic lenses.

Abstract: This invention relates to polymerizable ultraviolet light absorbers and yellow colorants and their use in ophthalmic lenses. In particular, this invention relates to polymerizable ultraviolet light absorbing methane compounds and yellow compounds of the methine and anthraquinone classes that block ultraviolet light and/or violet-blue light transmission through ophthalmic lenses.

Abstract: This invention relates to polymerizable ultraviolet light absorbers and yellow colorants and their use in ophthalmic lenses. In particular, this invention relates to polymerizable ultraviolet light absorbing methine compounds and yellow compounds of the methine and anthraquinone classes that block ultraviolet light and/or violet-blue light transmission through ophthalmic lenses.

Abstract: This invention relates to polymerizable ultraviolet light absorbers and yellow colorants and their use in ophthalmic lenses. In particular, this invention relates to polymerizable ultraviolet light absorbing methane compounds and yellow compounds of the methine and anthraquinone classes that block ultraviolet light and/or violet-blue light transmission through ophthalmic lenses.

Abstract: Polymerizable light absorbing azo dyes are disclosed useful as monomers in the formation of devices such as, but not limited to ocular lenses. Specifically, intraocular lenses (IOL) are disclosed wherein one or more of the light absorbing dye is covalently bonded to other structural polymers though ethylene unsaturated groups. The resulting IOLs possess light absorbing properties without significant amounts of free (un-bound) azo dye molecules present in the final structural polymer matrix.

Abstract: Ophthalmic devices are provided having a violet-light vertical cut-off filter abruptly absorbs light between the wave lengths of between approximately and 400 nm and 450 nm such that a curve when plotted as percent transmission versus wavelength has the shape as depicted in FIG. 2. In one embodiment the ophthalmic devices are made from acrylates and the light absorbing compound is an Eastman Yellow 035 MA dye.