Patents by Inventor Max B. Kelz

Max B. Kelz has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • In situ cloning from pathological tissue specimens
    Patent number: 8945883
    Abstract: The present invention pertains to methods related to cloning nucleic acids from biological samples, particularly pathological tissue samples. This method includes hybridizing a population of oligonucleotide sequence probes comprising degenerate sequence tags to a fixed tissue, isolating the hybridized oligonucleotide sequence probes and amplifying the sequence tags in the hybridized oligonucleotide sequence probes. This method can be utilized to identify genes associated with disease and to quantitate the expression of disease-related transcripts. The method can also be used to identify truncated mRNAs.
    Type: Grant
    Filed: March 21, 2013
    Date of Patent: February 3, 2015
    Assignee: The Trustees of the University of Pennsylvania
    Inventors: James H. Eberwine, Max B. Kelz
  • In situ cloning from pathological tissue specimens
    Patent number: 8530196
    Abstract: The present invention pertains to methods related to cloning nucleic acids from biological samples, particularly pathological tissue samples. This method includes hybridizing a population of oligonucleotide sequence probes comprising degenerate sequence tags to a fixed tissue, isolating the hybridized oligonucleotide sequence probes and amplifying the sequence tags in the hybridized oligonucleotide sequence probes. This method can be utilized to identify genes associated with disease and to quantitate the expression of disease-related transcripts. The method can also be used to identify truncated mRNAs.
    Type: Grant
    Filed: April 9, 2007
    Date of Patent: September 10, 2013
    Assignee: The Trustees of the Univeristy of Pennsylvania
    Inventors: James H. Eberwine, Max B. Kelz
  • In situ cloning from pathological tissue specimens
    Publication number: 20090023593
    Abstract: The present invention pertains to methods related to cloning nucleic acids from biological samples, particularly pathological tissue samples. This method includes hybridizing a population of oligonucleotide sequence probes comprising degenerate sequence tags to a fixed tissue, isolating the hybridized oligonucleotide sequence probes and amplifying the sequence tags in the hybridized oligonucleotide sequence probes. This method can be utilized to identify genes associated with disease and to quantitate the expression of disease-related transcripts. The method can also be used to identify truncated mRNAs.
    Type: Application
    Filed: April 9, 2007
    Publication date: January 22, 2009
    Applicant: The Trustees of the University of Pennsylvania
    Inventors: James H. Eberwine, Max B. Kelz