Patents by Inventor Max CIARLET

Max CIARLET has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20250161436
    Abstract: Provided are compositions pharmaceutical compositions, comprising two or more virus-like particles (VLPs), wherein a first virus-like particle (VLP) comprises a first component comprising a respiratory syntactical virus (RSV) F protein ectodomain or antigenic variant thereof; and a second virus-like particle (VLP) comprises a first component comprising a comprises a human metapneumovirus (hMPV) F protein ectodomain or antigenic variant thereof. Further provided are methods of using said compositions for vaccination.
    Type: Application
    Filed: November 7, 2024
    Publication date: May 22, 2025
    Inventors: ANDREW L. FELDHAUS, DOUGLAS A. HOLTZMAN, MAX CIARLET, NIRANJAN KANESA-THASAN
  • Publication number: 20220168413
    Abstract: The present disclosure relates to vaccine compositions comprising a) antigens from at least three different strains of influenza vims, preferably at least four different strains of influenza vims, and b) an oil-in-water emulsion adjuvant, wherein the amount of the oil-in-water emulsion adjuvant is greater than an amount of an oil-in-water emulsion adjuvant in a standard-dose adjuvanted multivalent influenza vaccine. Additionally, the total amount of the antigens in the vaccine compositions may be greater than a total amount of antigens in a standard-dose adjuvanted multivalent influenza vaccine. In preferred aspects, the present disclosure further describes uses of these vaccine compositions for safe and effective induction of immune responses in adults at least 65 years of age.
    Type: Application
    Filed: February 24, 2020
    Publication date: June 2, 2022
    Inventors: Max CIARLET, Christian MANDL, Andrea FELLER, Brett LEAV, Gillis OTTEN