Patents by Inventor Max Espensen

Max Espensen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Substituted Imidazo[4,5-c]pyridine Compounds and Compositions Thereof
    Publication number: 20230110165
    Abstract: Compound of formula (I) or a pharmaceutically acceptable salt, or N-oxide thereof, that are inhibitors of SSAO activity: where V, W, X, Y, Z, R1, and R3 are as defined herein.
    Type: Application
    Filed: October 7, 2022
    Publication date: April 13, 2023
    Inventors: Max Espensen, Lee Patient, David Evans, Edward Savory, Iain Simpson
  • Substituted imidazo[4,5-c]pyridine compounds and compositions thereof
    Patent number: 11512082
    Abstract: Compound of formula (I) or a pharmaceutically acceptable salt, or N-oxide thereof, that are inhibitors of SSAO activity: where V, W, X, Y, Z, R1, and R3 are as defined herein.
    Type: Grant
    Filed: February 7, 2020
    Date of Patent: November 29, 2022
    Assignee: Proximagen, LLC
    Inventors: Max Espensen, Lee Patient, David Evans, Edward Savory, Iain Simpson
  • Imidazo[4,5-c]pyridine and pyrrolo[2,3-c]pyridine derivatives as SSAO inhibitors
    Patent number: 10968223
    Abstract: A process for the preparation of a compound of formula (Ia) or a pharmaceutically acceptable salt, or N-oxide thereof that includes reacting a compound of formula (IIIa) or (Va) with a compound of formula (IX) to form the compound of formula (Ia)
    Type: Grant
    Filed: July 20, 2020
    Date of Patent: April 6, 2021
    Assignee: Proximagen, LLC
    Inventors: Max Espensen, Lee Patient, David Evans, Iain Simpson, Edward Savory
  • IMIDAZO[4,5-C]PYRIDINE AND PYRROLO[2,3-C]PYRIDINE DERIVATIVES AS SSAO INHIBITORS
    Publication number: 20200347059
    Abstract: A process for the preparation of a compound of formula (Ia) or a pharmaceutically acceptable salt, or N-oxide thereof that includes reacting a compound of formula (IIIa) or (Va) with a compound of formula (IX) to form the compound of formula (Ia)
    Type: Application
    Filed: July 20, 2020
    Publication date: November 5, 2020
    Applicant: PROXIMAGEN, LLC
    Inventors: Max ESPENSEN, Lee PATIENT, David EVANS, Iain SIMPSON, Edward SAVORY
  • Imidazo[4,5-c]pyridine and pyrrolo[2,3-c]pyridine derivatives as SSAO inhibitors
    Patent number: 10766897
    Abstract: The compounds of formula (I) are inhibitors of SSAO activity wherein V, W, X, Y, Z, R1 and R2 are as defined in the claims.
    Type: Grant
    Filed: August 16, 2019
    Date of Patent: September 8, 2020
    Assignee: PROXIMAGEN, LLC
    Inventors: Max Espensen, Lee Patient, David Evans, Iain Simpson, Edward Savory
  • COMPOUNDS
    Publication number: 20200262835
    Abstract: Compound of formula (I) or a pharmaceutically acceptable salt, or N-oxide thereof, that are inhibitors of SSAO activity: where V, W, X, Y, Z, R1, and R3 are as defined herein.
    Type: Application
    Filed: February 7, 2020
    Publication date: August 20, 2020
    Applicant: PROXIMAGEN, LLC
    Inventors: Max ESPENSEN, Lee PATIENT, David EVANS, Edward SAVORY, Iain SIMPSON
  • Compounds
    Patent number: 10590125
    Abstract: The present invention relates to compounds which are inhibitors of SSAO activity. The invention also relates to pharmaceutical compositions comprising these compounds and to the use of these compounds in the treatment or prevention of medical conditions wherein inhibition of SSAO activity is beneficial, such as inflammatory diseases, immune disorders and the inhibition of tumor growth.
    Type: Grant
    Filed: July 20, 2016
    Date of Patent: March 17, 2020
    Assignee: PROXIMAGEN, LLC
    Inventors: Max Espensen, Lee Patient, David Evans, Edward Savory, Iain Simpson
  • IMIDAZO[4,5-C]PYRIDINE AND PYRROLO[2,3-C]PYRIDINE DERIVATIVES AS SSAO INHIBITORS
    Publication number: 20200002335
    Abstract: The compounds of formula (I) are inhibitors of SSAO activity wherein V, W, X, Y, Z, R1 and R2 are as defined in the claims.
    Type: Application
    Filed: August 16, 2019
    Publication date: January 2, 2020
    Applicant: PROXIMAGEN, LLC
    Inventors: Max ESPENSEN, Lee PATIENT, David EVANS, Iain SIMPSON, Edward SAVORY
  • Imidazo[4,5-C]pyridine and pyrrolo[2,3-C]pyridine derivatives as SSAO inhibitors
    Patent number: 10428066
    Abstract: The compounds of formula (I) are inhibitors of SSAO activity wherein V, W, X, Y, Z, R1 and R2 are as defined in the claims.
    Type: Grant
    Filed: March 5, 2018
    Date of Patent: October 1, 2019
    Assignee: PROXIMAGEN, LLC
    Inventors: Max Espensen, Lee Patient, David Evans, Iain Simpson, Edward Savory
  • Substituted imidazo[4,5-c]pyridines as SSAO inhibitors
    Patent number: 10065954
    Abstract: Specific compounds of formula (Ia): and pharmaceutically acceptable salts thereof. Pharmaceutical compositions of the specific compounds of formula (Ia) and pharmaceutically acceptable salts thereof. A method for inhibiting tumor growth in a subject that includes administering to the subject an effective amount of a compound selected from the specific compounds of formula (Ia) and pharmaceutically acceptable salts thereof. A method for modulating semicarbazide-sensitive amine oxidase activity in a subject that includes administering to the subject an effective amount of a compound selected from the specific compounds of formula (Ia) and pharmaceutically acceptable salts thereof.
    Type: Grant
    Filed: September 17, 2015
    Date of Patent: September 4, 2018
    Assignee: PROXIMAGEN LIMITED
    Inventors: Max Espensen, Lee Patient, Edward Savory
  • IMIDAZO[4,5-C]PYRIDINE AND PYRROLO[2,3-C]PYRIDINE DERIVATIVES AS SSAO INHIBITORS
    Publication number: 20180194763
    Abstract: The compounds of formula (I) are inhibitors of SSAO activity wherein V, W, X, Y, Z, R1 and R2 are as defined in the claims.
    Type: Application
    Filed: March 5, 2018
    Publication date: July 12, 2018
    Applicant: PROXIMAGEN LIMITED
    Inventors: Max Espensen, Lee Patient, David Evans, Iain Simpson, Edward Savory
  • Imidazo[4,5-C]pyridine and pyrrolo[2,3-C]pyridine derivatives as SSAO inhibitors
    Patent number: 9951068
    Abstract: The compounds of formula (I) are inhibitors of SSAO activity wherein V, W, X, Y, Z, R1 and R2 are as defined in the claims.
    Type: Grant
    Filed: May 11, 2017
    Date of Patent: April 24, 2018
    Assignee: PROXIMAGEN LIMITED
    Inventors: Max Espensen, Lee Patient, David Evans, Iain Simpson, Edward Savory
  • IMIDAZO[4,5-C]PYRIDINE DERIVED SSAO INHIBITORS
    Publication number: 20170362218
    Abstract: A compound as set out in claim 1, and the use of the same in therapy.
    Type: Application
    Filed: September 17, 2015
    Publication date: December 21, 2017
    Inventors: Max Espensen, Lee Patient, Edward Savory
  • IMIDAZO[4,5-C]PYRIDINE AND PYRROLO[2,3-C]PYRIDINE DERIVATIVES AS SSAO INHIBITORS
    Publication number: 20170247378
    Abstract: The compounds of formula (I) are inhibitors of SSAO activity wherein V, W, X, Y, Z, R1 and R2 are as defined in the claims.
    Type: Application
    Filed: May 11, 2017
    Publication date: August 31, 2017
    Inventors: Max Espensen, Lee Patient, David Evans, Iain Simpson, Edward Savory
  • Imidazo[4,5-C]pyridine and pyrrolo[2,3-C]pyridine derivatives as SSAO inhibitors
    Patent number: 9676769
    Abstract: The compounds of formula (I) are inhibitors of semicarbazide-sensitive amine oxidase (SSAO) activity useful in the treatment of inflammation, an inflammatory disease, an immune or an autoimmune disorder, or inhibition of tumor growth.
    Type: Grant
    Filed: March 13, 2014
    Date of Patent: June 13, 2017
    Assignee: Proximagen Limited
    Inventors: Max Espensen, Lee Patient, David Evans, Iain Simpson, Edward Savory
  • NEW COMPOUNDS
    Publication number: 20160326172
    Abstract: The present invention relates to compounds which are inhibitors of SSAO activity. The invention also relates to pharmaceutical compositions comprising these compounds and to the use of these compounds in the treatment or prevention of medical conditions wherein inhibition of SSAO activity is beneficial, such as inflammatory diseases, immune disorders and the inhibition of tumor growth.
    Type: Application
    Filed: July 20, 2016
    Publication date: November 10, 2016
    Inventors: Max Espensen, Lee Patient, David Evans, Edward Savory, Iain Simpson
  • Substituted imidazo[4,5-c]pyridine compounds and compositions thereof
    Patent number: 9428498
    Abstract: The present invention relates to compounds which are inhibitors of SSAO activity. The invention also relates to pharmaceutical compositions comprising these compounds and to the use of these compounds in the treatment or prevention of medical conditions wherein inhibition of SSAO activity is beneficial, such as inflammatory diseases, immune disorders and the inhibition of tumor growth.
    Type: Grant
    Filed: March 13, 2014
    Date of Patent: August 30, 2016
    Assignee: Proximagen Limited
    Inventors: Max Espensen, Lee Patient, David Evans, Edward Savory, Iain Simpson
  • IMIDAZO[4,5-C]PYRIDINE AND PYRROLO[2,3-C]PYRIDINE DERIVATIVES AS SSAO INHIBITORS
    Publication number: 20160046622
    Abstract: The compounds of formula (I) are inhibitors of semicarbazide-sensitive amine oxidase (SSAO) activity useful in the treatment of inflammation, an inflammatory disease, an immune or an autoimmune disorder, or inhibition of tumour growth.
    Type: Application
    Filed: March 13, 2014
    Publication date: February 18, 2016
    Inventors: Max Espensen, Lee Patient, David Evans, Iain Simpson, Edward Savory
  • NEW COMPOUNDS
    Publication number: 20150258101
    Abstract: The present invention provides certain compounds according to formula (I) which are inhibitors of SSAO activity wherein V, W, X, Y, Z, R1 and R2 are as defined in the specification.
    Type: Application
    Filed: March 12, 2015
    Publication date: September 17, 2015
    Inventors: Max Espensen, Edward Savory
  • NEW COMPOUNDS
    Publication number: 20140275040
    Abstract: The present invention relates to compounds which are inhibitors of SSAO activity. The invention also relates to pharmaceutical compositions comprising these compounds and to the use of these compounds in the treatment or prevention of medical conditions wherein inhibition of SSAO activity is beneficial, such as inflammatory diseases, immune disorders and the inhibition of tumor growth.
    Type: Application
    Filed: March 13, 2014
    Publication date: September 18, 2014
    Applicant: Proximagen Limited
    Inventors: Max Espensen, Lee Patient, David Evans, Edward Savory, Iain Simpson