Patents by Inventor Max Gottesman

Max Gottesman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Purified bacterial protein which stimulates ligation of nucleic acid molecules
    Patent number: 5229273
    Abstract: The subject invention provides a purified protein having a molecular weight of about 22.8 kDa and the amino acid sequence shown in FIG. 2. The invention further provides a method of producing the 22.8 kDa protein which comprises culturing the host cell comprising an expression vector under conditions such that the expression vector contained therein expresses the protein and recovering from the host cell the protein so expressed. Also provided is a method of ligating separate nucleic acid molecules which comprises contacting the molecules with the 22.8 kDa protein under conditions such that the molecules are ligated together.
    Type: Grant
    Filed: May 30, 1990
    Date of Patent: July 20, 1993
    Assignee: The Trustees of Columbia University in the City of New York
    Inventors: Max Gottesman, William Holloman