Patents by Inventor Max Joseph Lab

Max Joseph Lab has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Scanning ion conductance microscopy for the investigation of living cells
    Patent number: 8006316
    Abstract: A method for interrogating a surface using scanning probe microscopy comprises bringing a scanning probe into proximity with the surface and controlling the position of the probe relative to the surface to maintain a constant distance, characterized in that pressure is applied to the surface by a regulated flow of liquid through the probe, with subsequent monitoring of the position of the probe, wherein movement of the probe indicates a consequent movement of the surface.
    Type: Grant
    Filed: August 1, 2007
    Date of Patent: August 23, 2011
    Assignee: Ionscope Ltd
    Inventors: Yuri Evgenievich Korchev, Max Joseph Lab, Daniel Paulo Sànchez-Herrera
  • SCANNING ION CONDUCTANCE MICROSCOPY FOR THE INVESTIGATION OF LIVING CELLS
    Publication number: 20090260114
    Abstract: A method for interrogating a surface using scanning probe microscopy comprises bringing a scanning probe into proximity with the surface and controlling the position of the probe relative to the surface to maintain a constant distance, characterized in that pressure is applied to the surface by a regulated flow of liquid through the probe, with subsequent monitoring of the position of the probe, wherein movement of the probe indicates a consequent movement of the surface.
    Type: Application
    Filed: August 1, 2007
    Publication date: October 15, 2009
    Applicant: Ionscope Limited
    Inventors: Yuri Evgenievich Korchev, Max Joseph Lab, Daniel Paulo Sanchez-Herrera
  • Patch-clamping and its use in analyzing subcellular features
    Patent number: 7057171
    Abstract: The present invention pertains to a method for investigating a cell, comprising bringing a probe close to the surface of the cell or part thereof, at a controlled distance therefrom; and into contact with the surface, essentially normal to the surface, to achieve patch-clamping.
    Type: Grant
    Filed: March 22, 2002
    Date of Patent: June 6, 2006
    Assignee: Imperial College Innovations Limited
    Inventors: Yuri Evgenievich Korchev, Max Joseph Lab
  • Optical microscopy and its use in the study of cells
    Patent number: 6929934
    Abstract: The present invention pertains to an apparatus for imaging an object, comprising a probe via which an assay component may be delivered; a sensor to detect ion current; and means for controlling the position of the probe relative to the object in response to the ion current. Such apparatus can be used to image live cells, without affecting them, in solution, e.g., using light, wherein the distance between probe and cell is less than the wavelength of light.
    Type: Grant
    Filed: April 17, 2000
    Date of Patent: August 16, 2005
    Assignee: Imperial College Innovations, Ltd.
    Inventors: Yuri Evgenievich Korchev, David Klenerman, Max Joseph Lab
  • Patch-clamping and its use in analysing subcellular features
    Publication number: 20040140427
    Abstract: The present invention pertains to a method for investigating a cell, comprising bringing a probe close to the surface of the cell or part thereof, at a controlled distance therefrom; and into contact with the surface, essentially normal to the surface, to achieve patch-clamping.
    Type: Application
    Filed: March 15, 2004
    Publication date: July 22, 2004
    Inventors: Yuri Evgenievich Korchev, Max Joseph Lab