Patents by Inventor Max Seibold

Max Seibold has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS AND COMPOSITIONS FOR RISK PREDICTION, DIAGNOSIS, PROGNOSIS, AND TREATMENT OF PULMONARY DISORDERS
    Publication number: 20230313307
    Abstract: The invention provides diagnostic and therapeutic targets for pulmonary disease, in particular, fibrotic lung disease. The inventors have found that a genetic variant MUC5B gene is associated with increased expression of the gene, increased risk of developing a pulmonary disease, and an improved prognosis and survival among those developing the pulmonary disease.
    Type: Application
    Filed: April 25, 2023
    Publication date: October 5, 2023
    Inventors: David A. Schwartz, Max Seibold
  • Methods and compositions for risk prediction, diagnosis, prognosis, and treatment of pulmonary disorders
    Patent number: 11649503
    Abstract: The invention provides diagnostic and therapeutic targets for pulmonary disease, in particular, fibrotic lung disease. The inventors have found that a genetic variant MUC5B gene is associated with increased expression of the gene, increased risk of developing a pulmonary disease, and an improved prognosis and survival among those developing the pulmonary disease.
    Type: Grant
    Filed: November 6, 2020
    Date of Patent: May 16, 2023
    Assignee: National Jewish Health
    Inventors: David A. Schwartz, Max Seibold
  • METHODS OF MAKING PLURIPOTENT STEM CELLS AND USES THEREOF
    Publication number: 20230138022
    Abstract: Disclosed herein are methods to reliably and robustly generate a pure population of airway basal cells that are capable of producing a normal mucociliary epithelium. Such basal cells may be used to treat chronic respiratory diseases, such as cystic fibrosis, chronic obstructive pulmonary disease, and asthma.
    Type: Application
    Filed: April 1, 2021
    Publication date: May 4, 2023
    Inventors: Max A. SEIBOLD, Yingchun LI
  • METHODS OF DETECTING AND TREATING AIRWAY INFLAMMATORY DISEASES
    Publication number: 20210333289
    Abstract: The present invention is related to novel methods for identifying and/or diagnosing and/or treating a population of subjects that are at risk for developing and/or have an inflammatory disease of the airways, including type 2 cytokine-driven airway inflammation.
    Type: Application
    Filed: February 11, 2021
    Publication date: October 28, 2021
    Inventors: Max SEIBOLD, Jamie EVERMAN
  • METHODS AND COMPOSITIONS FOR RISK PREDICTION, DIAGNOSIS, PROGNOSIS, AND TREATMENT OF PULMONARY DISORDERS
    Publication number: 20210198738
    Abstract: The invention provides diagnostic and therapeutic targets for pulmonary disease, in particular, fibrotic lung disease. The inventors have found that a genetic variant MUC5B gene is associated with increased expression of the gene, increased risk of developing a pulmonary disease, and an improved prognosis and survival among those developing the pulmonary disease.
    Type: Application
    Filed: November 6, 2020
    Publication date: July 1, 2021
    Inventors: David A. Schwartz, Max Seibold
  • Methods and compositions for risk prediction, diagnosis, prognosis, and treatment of pulmonary disorders
    Patent number: 10858707
    Abstract: The invention provides diagnostic and therapeutic targets for pulmonary disease, in particular, fibrotic lung disease. The inventors have found that a genetic variant MUC5B gene is associated with increased expression of the gene, increased risk of developing a pulmonary disease, and an improved prognosis and survival among those developing the pulmonary disease.
    Type: Grant
    Filed: November 2, 2017
    Date of Patent: December 8, 2020
    Assignee: NATIONAL JEWISH HEALTH
    Inventors: David A. Schwartz, Max Seibold
  • Methods of Identifying and Treating Subjects having Inflammatory Subphenotypes of Asthma
    Publication number: 20190161800
    Abstract: The present invention is directed toward novel methods to identify and treat subjects having inflammatory asthma subphenotypes.
    Type: Application
    Filed: September 11, 2018
    Publication date: May 30, 2019
    Inventors: Max A. Seibold, Esteban Burchard
  • METHODS OF DETECTING AND TREATING AIRWAY INFLAMMATORY DISEASES
    Publication number: 20190064185
    Abstract: The present invention is related to novel methods for identifying and/or diagnosing and/or treating a population of subjects that are at risk for developing and/or have an inflammatory disease of the airways, including type 2 cytokine-driven airway inflammation.
    Type: Application
    Filed: February 24, 2017
    Publication date: February 28, 2019
    Applicant: National Jewish Health
    Inventors: Max SEIBOLD, Jamie EVERMAN
  • METHODS AND COMPOSITIONS FOR RISK PREDICTION, DIAGNOSIS, PROGNOSIS, AND TREATMENT OF PULMONARY DISORDERS
    Publication number: 20190040467
    Abstract: The invention provides diagnostic and therapeutic targets for pulmonary disease, in particular, fibrotic lung disease. The inventors have found that a genetic variant MUC5B gene is associated with increased expression of the gene, increased risk of developing a pulmonary disease, and an improved prognosis and survival among those developing the pulmonary disease.
    Type: Application
    Filed: November 2, 2017
    Publication date: February 7, 2019
    Inventors: David A. Schwartz, Max Seibold
  • METHODS AND COMPOSITIONS FOR RISK PREDICTION, DIAGNOSIS, PROGNOSIS, AND TREATMENT OF PULMONARY DISORDERS
    Publication number: 20170183730
    Abstract: The invention provides diagnostic and therapeutic targets for pulmonary disease, in particular, fibrotic lung disease. The inventors have found that a genetic variant MUC5B gene is associated with increased expression of the gene, increased risk of developing a pulmonary disease, and an improved prognosis and survival among those developing the pulmonary disease.
    Type: Application
    Filed: July 22, 2016
    Publication date: June 29, 2017
    Inventors: David A. Schwartz, Max Seibold
  • METHODS AND COMPOSITIONS FOR RISK PREDICTION, DIAGNOSIS, PROGNOSIS, AND TREATMENT OF PULMONARY DISORDERS
    Publication number: 20140220570
    Abstract: The invention provides diagnostic and therapeutic targets for pulmonary disease, in particular, fibrotic lung disease. The inventors have found that a genetic variant MUC5B gene is associated with increased expression of the gene, increased risk of developing a pulmonary disease, and an improved prognosis and survival among those developing the pulmonary disease.
    Type: Application
    Filed: February 3, 2014
    Publication date: August 7, 2014
    Applicant: National Jewish Health
    Inventors: David A. Schwartz, Max Seibold
  • Methods and compositions for risk prediction, diagnosis, prognosis, and treatment of pulmonary disorders
    Patent number: 8673565
    Abstract: The invention provides diagnostic and therapeutic targets for pulmonary disease, in particular, fibrotic lung disease. The inventors have found that a genetic variant MUC5B gene is associated with increased expression of the gene, increased risk of developing a pulmonary disease, and an improved prognosis and survival among those developing the pulmonary disease.
    Type: Grant
    Filed: January 26, 2011
    Date of Patent: March 18, 2014
    Assignee: National Jewish Health
    Inventors: David A. Schwartz, Max Seibold
  • METHODS AND COMPOSITIONS FOR RISK PREDICTION, DIAGNOSIS, PROGNOSIS, AND TREATMENT OF PULMONARY DISORDERS
    Publication number: 20110217315
    Abstract: The invention provides diagnostic and therapeutic targets for pulmonary disease, in particular, fibrotic lung disease. The inventors have found that a genetic variant MUC5B gene is associated with increased expression of the gene, increased risk of developing a pulmonary disease, and an improved prognosis and survival among those developing the pulmonary disease.
    Type: Application
    Filed: January 26, 2011
    Publication date: September 8, 2011
    Inventors: David A. Schwartz, Max Seibold