Abstract: An article includes an identifier fiber. The identifier fiber includes a photonic structure that, upon illumination, produces an optical response having an optical parameter value. The optical parameter value, at least in part, identifies a particular article characteristic. The inclusion of the identifier fiber in the article indicates, at least in part, that the article has the particular article characteristic.

Abstract: A sensor device includes a substrate having a plurality of cuts through the substrate to define a set of substrate sections, the substrate being flexible, and a plurality of sensor structures supported by the substrate, each sensor structure of the plurality of sensor structures being disposed at a respective substrate section of the set of substrate sections. Deformation of the substrate deforms each respective substrate section of the set of substrate sections such that each respective substrate section is deformed to a respective extent. Each sensor structure of the plurality of sensor structures is configured to provide an indication of the respective extent of the deformation.

Abstract: The following relates generally to administering and delivering medications to patients. In some embodiments, an in-home appliance may place an ingestible ingredient (e.g., an active pharmaceutical ingredient (API) of a medication) on a physical substrate to create a distributable/retrievable object, which is distributed to a subject. The subject may then consume at least a portion of the ingestible ingredient, and then return at least a portion of the distributable/retrievable object to the appliance. The appliance, upon receiving the object, can subsequently trigger secondary actions, including logging the consumption of the dose: authorizing the next dose to override security measures which would otherwise block access to additional doses: analyzing the returned object for biometrics or remaining amount of ingestible ingredients, etc.

Abstract: Systems and methods for fabricating an adjustable width kirigami structure for tissue fabrication and testing are disclosed. An example method includes forming, by a laser cutting device, at least two kirigami structure substrates that include a plurality of bendable pillars. The example method further includes bending each of the plurality of bendable pillars to an erected position for each of the at least two kirigami structure substrates. The example method further includes layering a first kirigami structure substrate of the at least two kirigami structure substrates over a second kirigami structure substrate of the at least two kirigami structure substrates, such that the first kirigami structure substrate is antiparallel relative to the second kirigami structure substrate, to generate an adjustable width kirigami structure.

Abstract: Disclosed herein is a method and apparatus for synthesizing co-crystals from the vapor phase without the need for liquid solvent. Also disclosed herein are co-crystals formed from the vapor phase, substrates coated with said co-crystals, pharmaceutical compositions thereof and apparatuses for producing said co-crystals.

Abstract: A solid film structure formed of multiple solid film insert layers each having different functionality is provided. The solid film structure forms a bio-chemotronic structure having an actuator thin film layer with one or more low molecular weight organic active agents that may be activated, a sensor thin film layer that includes one or more sensors for measuring a direct or indirect response from a target to the one or more active agents, and a control thin film layer configured to individually control activation of the active agents in the actuator layer, e.g., according to a protocol.

Abstract: Disclosed herein are solvent-free vapor deposition methods comprising: vaporizing a bulk cocrystalline material to form a vapor, entraining the vapor into a carrier gas, and depositing a film comprising the cocrystalline material on one or more discrete regions of a substrate. Also provided are solid films and articles comprising a surface of a solid substrate having one or more discrete regions patterned with a deposited solid film of a cocrystalline material, produced by the solvent-free vapor deposition methods disclosed herein.

Abstract: A sensor device includes a substrate having a plurality of cuts through the substrate to define a set of substrate sections, the substrate being flexible, and a plurality of sensor structures supported by the substrate, each sensor structure of the plurality of sensor structures being disposed at a respective substrate section of the set of substrate sections. Deformation of the substrate deforms each respective substrate section of the set of substrate sections such that each respective substrate section is deformed to a respective extent. Each sensor structure of the plurality of sensor structures is configured to provide an indication of the respective extent of the deformation.

Abstract: Disclosed herein are systems for tracking patient medication protocol adherence, the system comprising a computing device for tracking the amount of an active pharmaceutical ingredient (Al) to be administered to the subject using an augmented utensil comprising a layered Al delivery structure formed. Also disclosed are methods of customizing drug delivery, and augmented utensils and methods of making the same.

Abstract: A device includes a support structure having a plurality of concentric cuts through the support structure that define a set of structure sections. The device also includes an insert assembly supported by the support structure at an inner structure section of the set of structure sections. The inner structure section is configured to tilt the insert assembly at a tilt angle in accordance with a displacement of a first outer structure section of the set of structure sections.

Abstract: A method of fabricating a thin film structure includes printing, using an electrohydrodynamic jet (e-jet) printing apparatus, a first layer comprising a first liquid ink, such that the first layer is supported by a substrate, curing the first layer; printing, using the e-jet printing apparatus, a second layer comprising a second liquid ink, such that the second layer is supported by the first layer, and curing the second layer.

Abstract: A device includes a support structure having a plurality of concentric cuts through the support structure that define a set of structure sections. The device also includes an insert assembly supported by the support structure at an inner structure section of the set of structure sections. The inner structure section is configured to tilt the insert assembly at a tilt angle in accordance with a displacement of a first outer structure section of the set of structure sections.

Abstract: A method of fabricating a thin film structure includes printing, using an electrohydrodynamic jet (e-jet) printing apparatus, a first layer comprising a first liquid ink, such that the first layer is supported by a substrate, curing the first layer; printing, using the e-jet printing apparatus, a second layer comprising a second liquid ink, such that the second layer is supported by the first layer, and curing the second layer.

Abstract: A method of fabricating a thin film structure includes printing, using an electrohydrodynamic jet (e-jet) printing apparatus, a first layer comprising a first liquid ink, such that the first layer is supported by a substrate, curing the first layer; printing, using the e-jet printing apparatus, a second layer comprising a second liquid ink, such that the second layer is supported by the first layer, and curing the second layer.

Abstract: Solid films and articles having a surface with discrete regions patterned with a deposited low molecular weight organic compound, such as pharmaceutical actives and new chemical entities, are provided. The organic compound may be present at ? about 99 mass % in the one or more discrete regions and may be crystalline or amorphous. The deposited organic compound may be deposited as a film having high surface area. The deposited organic compound exhibits enhanced solubility and bioavailability, by way of non-limiting example. Methods of organic vapor jet printing deposition method of such a low molecular weight organic compound in an inert gas stream are also provided.

Abstract: Disclosed herein is are methods and apparatuses for synthesizing deposited films of compounds (e.g., organic compounds such as a pharmaceutical active ingredient or a new chemical entity) on or in a variety of substrates, where such deposited compounds the desired stability under storage conditions, ease of handling, and yet enhanced dissolution properties when used in various assays. The disclosure further relates to methods of coating substrates, such as medical or diagnostic devices, with deposited films of organic compounds, as well as film-coated substrates.

Abstract: Disclosed herein is a method and apparatus for synthesizing co-crystals from the vapor phase without the need for liquid solvent. Also disclosed herein are co-crystals formed from the vapor phase, substrates coated with said co-crystals, pharmaceutical compositions thereof and apparatuses for producing said co-crystals.

Abstract: A method of fabricating a thin film structure includes printing, using an electrohydrodynamic jet (e-jet) printing apparatus, a first layer comprising a first liquid ink, such that the first layer is supported by a substrate, curing the first layer; printing, using the e-jet printing apparatus, a second layer comprising a second liquid ink, such that the second layer is supported by the first layer, and curing the second layer.

Abstract: A device includes a support structure having a plurality of concentric cuts through the support structure that define a set of structure sections. The device also includes an insert assembly supported by the support structure at an inner structure section of the set of structure sections. The inner structure section is configured to tilt the insert assembly at a tilt angle in accordance with a displacement of a first outer structure section of the set of structure sections.

Abstract: A sensor device includes a substrate having a plurality of cuts through the substrate to define a set of substrate sections, the substrate being flexible, and a plurality of sensor structures supported by the substrate, each sensor structure of the plurality of sensor structures being disposed at a respective substrate section of the set of substrate sections. Deformation of the substrate deforms each respective substrate section of the set of substrate sections such that each respective substrate section is deformed to a respective extent. Each sensor structure of the plurality of sensor structures is configured to provide an indication of the respective extent of the deformation.