Patents by Inventor Max Shtein

Max Shtein has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 12208227
    Abstract: A solid film structure formed of multiple solid film insert layers each having different functionality is provided. The solid film structure forms a bio-chemotronic structure having an actuator thin film layer with one or more low molecular weight organic active agents that may be activated, a sensor thin film layer that includes one or more sensors for measuring a direct or indirect response from a target to the one or more active agents, and a control thin film layer configured to individually control activation of the active agents in the actuator layer, e.g., according to a protocol.
    Type: Grant
    Filed: August 24, 2018
    Date of Patent: January 28, 2025
    Assignee: THE REGENTS OF THE UNIVERSITY OF MICHIGAN
    Inventors: Max Shtein, Olga Shalev, Y. Eugene Shteyn
  • Publication number: 20240425966
    Abstract: Disclosed herein are solvent-free vapor deposition methods comprising: vaporizing a bulk cocrystalline material to form a vapor, entraining the vapor into a carrier gas, and depositing a film comprising the cocrystalline material on one or more discrete regions of a substrate. Also provided are solid films and articles comprising a surface of a solid substrate having one or more discrete regions patterned with a deposited solid film of a cocrystalline material, produced by the solvent-free vapor deposition methods disclosed herein.
    Type: Application
    Filed: September 9, 2022
    Publication date: December 26, 2024
    Inventors: Max Shtein, Shea Sanvordenker
  • Patent number: 12152910
    Abstract: A sensor device includes a substrate having a plurality of cuts through the substrate to define a set of substrate sections, the substrate being flexible, and a plurality of sensor structures supported by the substrate, each sensor structure of the plurality of sensor structures being disposed at a respective substrate section of the set of substrate sections. Deformation of the substrate deforms each respective substrate section of the set of substrate sections such that each respective substrate section is deformed to a respective extent. Each sensor structure of the plurality of sensor structures is configured to provide an indication of the respective extent of the deformation.
    Type: Grant
    Filed: November 14, 2019
    Date of Patent: November 26, 2024
    Assignee: THE REGENTS OF THE UNIVERSITY OF MICHIGAN
    Inventors: Erin Evke, Eugene Shteyn, Max Shtein
  • Publication number: 20240331827
    Abstract: Disclosed herein are systems for tracking patient medication protocol adherence, the system comprising a computing device for tracking the amount of an active pharmaceutical ingredient (Al) to be administered to the subject using an augmented utensil comprising a layered Al delivery structure formed. Also disclosed are methods of customizing drug delivery, and augmented utensils and methods of making the same.
    Type: Application
    Filed: October 29, 2021
    Publication date: October 3, 2024
    Inventors: Max Shtein, Y. Eugene Shteyn, Mohsen Moayer
  • Publication number: 20240297611
    Abstract: A device includes a support structure having a plurality of concentric cuts through the support structure that define a set of structure sections. The device also includes an insert assembly supported by the support structure at an inner structure section of the set of structure sections. The inner structure section is configured to tilt the insert assembly at a tilt angle in accordance with a displacement of a first outer structure section of the set of structure sections.
    Type: Application
    Filed: October 27, 2023
    Publication date: September 5, 2024
    Inventors: Max Shtein, Erin Evke, Michael Arwashan, Chao Huang
  • Patent number: 12036793
    Abstract: A method of fabricating a thin film structure includes printing, using an electrohydrodynamic jet (e-jet) printing apparatus, a first layer comprising a first liquid ink, such that the first layer is supported by a substrate, curing the first layer; printing, using the e-jet printing apparatus, a second layer comprising a second liquid ink, such that the second layer is supported by the first layer, and curing the second layer.
    Type: Grant
    Filed: June 14, 2023
    Date of Patent: July 16, 2024
    Assignee: The Regents of the University of Michigan
    Inventors: Brian Iezzi, Max Shtein, Zahra Afkhami Kheirabadi, Kira Barton
  • Patent number: 11831272
    Abstract: A device includes a support structure having a plurality of concentric cuts through the support structure that define a set of structure sections. The device also includes an insert assembly supported by the support structure at an inner structure section of the set of structure sections. The inner structure section is configured to tilt the insert assembly at a tilt angle in accordance with a displacement of a first outer structure section of the set of structure sections.
    Type: Grant
    Filed: August 6, 2021
    Date of Patent: November 28, 2023
    Assignee: The Regents of the University of Michigan
    Inventors: Max Shtein, Erin Evke, Michael Arwashan, Chao Huang
  • Publication number: 20230321977
    Abstract: A method of fabricating a thin film structure includes printing, using an electrohydrodynamic jet (e-jet) printing apparatus, a first layer comprising a first liquid ink, such that the first layer is supported by a substrate, curing the first layer; printing, using the e-jet printing apparatus, a second layer comprising a second liquid ink, such that the second layer is supported by the first layer, and curing the second layer.
    Type: Application
    Filed: June 14, 2023
    Publication date: October 12, 2023
    Inventors: Brian Iezzi, Max Shtein, Zahra Afkhami Kheirabadi, Kira Barton
  • Patent number: 11712889
    Abstract: A method of fabricating a thin film structure includes printing, using an electrohydrodynamic jet (e-jet) printing apparatus, a first layer comprising a first liquid ink, such that the first layer is supported by a substrate, curing the first layer; printing, using the e-jet printing apparatus, a second layer comprising a second liquid ink, such that the second layer is supported by the first layer, and curing the second layer.
    Type: Grant
    Filed: August 6, 2021
    Date of Patent: August 1, 2023
    Assignee: The Regents of the University of Michigan
    Inventors: Brian Iezzi, Max Shtein, Zahra Afkhami Kheirabadi, Kira Barton
  • Publication number: 20230044649
    Abstract: Solid films and articles having a surface with discrete regions patterned with a deposited low molecular weight organic compound, such as pharmaceutical actives and new chemical entities, are provided. The organic compound may be present at ? about 99 mass % in the one or more discrete regions and may be crystalline or amorphous. The deposited organic compound may be deposited as a film having high surface area. The deposited organic compound exhibits enhanced solubility and bioavailability, by way of non-limiting example. Methods of organic vapor jet printing deposition method of such a low molecular weight organic compound in an inert gas stream are also provided.
    Type: Application
    Filed: June 14, 2022
    Publication date: February 9, 2023
    Inventors: Olga Shalev, Max Shtein, Shreya Raghavan, Geeta Mehta
  • Publication number: 20220355289
    Abstract: Disclosed herein is are methods and apparatuses for synthesizing deposited films of compounds (e.g., organic compounds such as a pharmaceutical active ingredient or a new chemical entity) on or in a variety of substrates, where such deposited compounds the desired stability under storage conditions, ease of handling, and yet enhanced dissolution properties when used in various assays. The disclosure further relates to methods of coating substrates, such as medical or diagnostic devices, with deposited films of organic compounds, as well as film-coated substrates.
    Type: Application
    Filed: April 20, 2020
    Publication date: November 10, 2022
    Inventors: Max Shtein, Y. Eugene Shteyn, Steven Morris, Brian lezzi, Siddharth Borsadia, Joanna Ciatti, Katie Wei
  • Publication number: 20220048911
    Abstract: Disclosed herein is a method and apparatus for synthesizing co-crystals from the vapor phase without the need for liquid solvent. Also disclosed herein are co-crystals formed from the vapor phase, substrates coated with said co-crystals, pharmaceutical compositions thereof and apparatuses for producing said co-crystals.
    Type: Application
    Filed: December 11, 2019
    Publication date: February 17, 2022
    Inventors: Max Shtein, Siddharth Borsadia, Eugene Shteyn
  • Publication number: 20220045644
    Abstract: A device includes a support structure having a plurality of concentric cuts through the support structure that define a set of structure sections. The device also includes an insert assembly supported by the support structure at an inner structure section of the set of structure sections. The inner structure section is configured to tilt the insert assembly at a tilt angle in accordance with a displacement of a first outer structure section of the set of structure sections.
    Type: Application
    Filed: August 6, 2021
    Publication date: February 10, 2022
    Inventors: Max Shtein, Erin Evke, Michael Arwashan, Chao Huang
  • Publication number: 20220040976
    Abstract: A method of fabricating a thin film structure includes printing, using an electrohydrodynamic jet (e-jet) printing apparatus, a first layer comprising a first liquid ink, such that the first layer is supported by a substrate, curing the first layer; printing, using the e-jet printing apparatus, a second layer comprising a second liquid ink, such that the second layer is supported by the first layer, and curing the second layer.
    Type: Application
    Filed: August 6, 2021
    Publication date: February 10, 2022
    Inventors: Brian Iezzi, Max Shtein, Zahra Afkhami Kheirabadi, Kira Barton
  • Publication number: 20220003577
    Abstract: A sensor device includes a substrate having a plurality of cuts through the substrate to define a set of substrate sections, the substrate being flexible, and a plurality of sensor structures supported by the substrate, each sensor structure of the plurality of sensor structures being disposed at a respective substrate section of the set of substrate sections. Deformation of the substrate deforms each respective substrate section of the set of substrate sections such that each respective substrate section is deformed to a respective extent. Each sensor structure of the plurality of sensor structures is configured to provide an indication of the respective extent of the deformation.
    Type: Application
    Filed: November 14, 2019
    Publication date: January 6, 2022
    Inventors: Erin Evke, Eugene Shteyn, Max Shtein
  • Publication number: 20210145335
    Abstract: A solid film structure formed of multiple solid film insert layers each having different functionality is provided. The solid film structure forms a bio-chemotronic structure having an actuator thin film layer with one or more low molecular weight organic active agents that may be activated, a sensor thin film layer that includes one or more sensors for measuring a direct or indirect response from a target to the one or more active agents, and a control thin film layer configured to individually control activation of the active agents in the actuator layer, e.g., according to a protocol.
    Type: Application
    Filed: August 24, 2018
    Publication date: May 20, 2021
    Inventors: Max Shtein, Olga Shalev, Y. Eugene Shteyn
  • Patent number: 10637391
    Abstract: There is disclosed Kirigami-inspired structures for use in solar tracking applications. When coupled with thin-film active materials, the disclosed microstructures can track solar position and maximize solar power generation. In one embodiment, there is disclosed a photovoltaic system comprising a single-axis, or multi-axis solar tracking structure comprising a support structure made of a flexible material having a defined unit cell structure, and a flexible photovoltaic cell disposed on the support structure. There is also disclosed methods of making such structures in which the photovoltaic cell is mounted to the support structure by a direct-attachment bonding processes such as cold-welding.
    Type: Grant
    Filed: November 28, 2014
    Date of Patent: April 28, 2020
    Assignee: The Regents of the University of Michigan
    Inventors: Stephen R. Forrest, Kyusang Lee, Matthew Shlian, Chih-Wei Chien, Peicheng Ku, Aaron Lamoreux, Max Shtein
  • Publication number: 20180296494
    Abstract: Solid films and articles having a surface with discrete regions patterned with a deposited low molecular weight organic compound, such as pharmaceutical actives and new chemical entities, are provided. The organic compound may be present at ?about 99 mass % in the one or more discrete regions and may be crystalline or amorphous. The deposited organic compound may be deposited as a film having high surface area. The deposited organic compound exhibits enhanced solubility and bioavailability, by way of non-limiting example. Methods of organic vapor jet printing deposition method of such a low molecular weight organic compound in an inert gas stream are also provided.
    Type: Application
    Filed: June 6, 2016
    Publication date: October 18, 2018
    Applicant: THE REGENTS OF THE UNIVERSITY OF MICHIGAN
    Inventors: Olga Shalev, Max Shtein, Shreya Raghavan, Geeta Mehta
  • Publication number: 20160285410
    Abstract: There is disclosed Kirigami-inspired structures for use in solar tracking applications. When coupled with thin-film active materials, the disclosed microstructures can track solar position and maximize solar power generation. In one embodiment, there is disclosed a photovoltaic system comprising a single-axis, or multi-axis solar tracking structure comprising a support structure made of a flexible material having a defined unit cell structure, and a flexible photovoltaic cell disposed on the support structure. There is also disclosed methods of making such structures in which the photovoltaic cell is mounted to the support structure by a direct-attachment bonding processes such as cold-welding.
    Type: Application
    Filed: November 28, 2014
    Publication date: September 29, 2016
    Inventors: Stephen R. Forrest, Kyusang Lee, Matthew Shlian, Chih-Wei Chien, Peicheng Ku, Aaron Lamoreux, Max Shtein
  • Patent number: 9114981
    Abstract: An electrically pumped light emitting device emits a light when powered by a power source. The light emitting device includes a first electrode, a second electrode including an outer surface, and at least one active organic semiconductor disposed between the first and second electrodes. The device also includes a dye adjacent the outer surface of the second electrode such that the second electrode is disposed between the dye and the active organic semiconductor. A voltage applied by the power source across the first and second electrodes causes energy to couple from decaying dipoles into surface plasmon polariton modes, which then evanescently couple to the dye to cause the light to be emitted.
    Type: Grant
    Filed: November 24, 2010
    Date of Patent: August 25, 2015
    Assignee: The Regents of The University of Michigan
    Inventors: Kwang Hyup An, Max Shtein, Kevin P. Pipe