Abstract: An audio monitoring and mixing system comprising a portable monitoring circuit, a breakout box, and a distribution circuit. The portable monitoring circuit includes a mixer for mixing audio signals to provide a mixed audio signal to an individual musician and a feedthrough for patching out an instrument effects signal. The breakout box includes a feedthrough circuit for distributing the first plurality of audio signals to the portable monitoring circuit and a second feedthrough for patching through the instrument effects signal from the portable monitoring circuit and providing the signal to an instrument effects processor. The distribution circuit receives audio signals and providing selected ones of the audio signals to the portable monitoring system. The system also includes a single, multi-signal cable connecting the monitoring circuit to the breakout box and a single, multi-signal cable connecting the breakout box to the distribution circuit.