Patents by Inventor Max Werner Scheiwe
Max Werner Scheiwe has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20160367502Abstract: The invention relates to film coated pellets comprising an active ingredient having a high solubility in water. The invention also relates to methods of preparing said pellets and to cores comprising the active ingredient having a high solubility in water and to pharmaceutical compositions comprising the film coated pellets.Type: ApplicationFiled: December 19, 2013Publication date: December 22, 2016Inventors: Max-Werner SCHEIWE, Dieter SWATSCHEK, Isabel STEINHAUSER
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Patent number: 9301959Abstract: The invention relates to a process for the preparation of a pharmaceutical intermediate, comprising the steps of (i) mixing (a-i) sildenafil base, (b-i) wicking agent, (c-i) disintegrant, (d-i) optionally glidant; (ii) compacting the mixture; and (iii) milling the compacted material; and to an intermediate obtainable by that process. In addition, the invention relates to a process for the preparation of an orally dispersible tablet (hereinafter also referred to as an “orodispersible tablet”) comprising the intermediate of the invention, and to orodispersible tablets obtainable by that process.Type: GrantFiled: August 5, 2014Date of Patent: April 5, 2016Assignee: ratiopharm GmbHInventors: Sven Winter, Max-Werner Scheiwe, Dieter Swatschek
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Publication number: 20150133489Abstract: The invention relates to a process for the preparation of tablets containing moxifloxacin, comprising the steps of (i) providing moxifloxacin, pharmaceutically acceptable salts, solvates or hydrates thereof, optionally mixed with one or more pharmaceutical excipients; (ii) compacting it into a slug; (iii) granulating the slug; and (iv) compressing the resulting granules into tablets; and also tablets, granules and compacted material containing compacted moxifloxacin.Type: ApplicationFiled: November 14, 2014Publication date: May 14, 2015Inventors: Dieter Swatschek, Max Werner Scheiwe
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Patent number: 8933081Abstract: The invention relates to an orodispersible tablet comprising the components pharmaceutically acceptable sildenafil salt (a), polymeric adsorbent (b), in particular cation exchanger resin, sweetener (c), and flavoring (d) and, preferably, mucilage (e) and glidant (f). The invention furthermore relates to a process for the preparation of orodispersible tablets comprising a pharmaceutically acceptable sildenafil salt and to the use of a combination of cation exchanger resin and mucilage for masking the flavor of medicaments for treating erectile dysfunction.Type: GrantFiled: March 31, 2010Date of Patent: January 13, 2015Assignee: ratiopharm GmbHInventors: Sven Winter, Max-Werner Scheiwe
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Publication number: 20140343072Abstract: The invention relates to a process for the preparation of a pharmaceutical intermediate, comprising the steps of (i) mixing (a-i) sildenafil base, (b-i) wicking agent, (c-i) disintegrant, (d-i) optionally glidant; (ii) compacting the mixture; and (iii) milling the compacted material; and to an intermediate obtainable by that process. In addition, the invention relates to a process for the preparation of an orally dispersible tablet (hereinafter also referred to as an “orodispersible tablet”) comprising the intermediate of the invention, and to orodispersible tablets obtainable by that process.Type: ApplicationFiled: August 5, 2014Publication date: November 20, 2014Inventors: Sven Winter, Max-Werner Scheiwe, Dieter Swatschek
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Patent number: 8808739Abstract: The invention relates to a process for the preparation of a pharmaceutical intermediate, comprising the steps of (i) mixing (a-i) sildenafil base, (b-i) wicking agent, (c-i) disintegrant, (d-i) optionally glidant; (ii) compacting the mixture; and (iii) milling the compacted material; and to an intermediate obtainable by that process. In addition, the invention relates to a process for the preparation of an orally dispersible tablet (hereinafter also referred to as an “orodispersible tablet”) comprising the intermediate of the invention, and to orodispersible tablets obtainable by that process.Type: GrantFiled: December 22, 2010Date of Patent: August 19, 2014Assignee: ratiopharm GmbHInventors: Sven Winter, Max-Werner Scheiwe, Dieter Swatschek
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Publication number: 20140088107Abstract: The present invention relates to an aqueous ophthalmic preparation comprising a PGF2? analogue and at least one polyvinyl alcohol and the use thereof for the treatment of glaucoma and ocular hypertension.Type: ApplicationFiled: November 25, 2013Publication date: March 27, 2014Applicant: RATIOPHARM GMBHInventors: Dieter Swatscheck, Max-Werner Scheiwe, Michael Florenski
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Publication number: 20120295916Abstract: The invention relates to a process for the preparation of a pharmaceutical intermediate, comprising the steps of (i) mixing (a-i) sildenafil base, (b-i) wicking agent, (c-i) disintegrant, (d-i) optionally glidant; (ii) compacting the mixture; and (iii) milling the compacted material; and to an intermediate obtainable by that process. In addition, the invention relates to a process for the preparation of an orally dispersible tablet (hereinafter also referred to as an “orodispersible tablet”) comprising the intermediate of the invention, and to orodispersible tablets obtainable by that process.Type: ApplicationFiled: December 22, 2010Publication date: November 22, 2012Applicant: ratiopharm GmbHInventors: Sven Winter, Max-Werner Scheiwe, Dieter Swatschek
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Publication number: 20120071488Abstract: The invention relates to an orodispersible tablet comprising the components pharmaceutically acceptable sildenafil salt (a), polymeric adsorbent (b), in particular cation exchanger resin, sweetener (c), and flavoring (d) and, preferably, mucilage (e) and glidant (f).Type: ApplicationFiled: March 31, 2010Publication date: March 22, 2012Applicant: ratiopharm GmbHInventors: Sven Winter, Max-Werner Scheiwe
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Publication number: 20110293717Abstract: The invention relates to a process for the preparation of tablets containing moxifloxacin, comprising the steps of (i) providing moxifloxacin, pharmaceutically acceptable salts, solvates or hydrates thereof, optionally mixed with one or more pharmaceutical excipients; (ii) compacting it into a slug; (iii) granulating the slug; and (iv) compressing the resulting granules into tablets; and also tablets, granules and compacted material containing compacted moxifloxacin.Type: ApplicationFiled: December 4, 2009Publication date: December 1, 2011Applicant: ratiopharm GmbHInventors: Dieter Swatschek, Max Werner Scheiwe
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Publication number: 20110281912Abstract: The present invention relates to an oral dispersible tablet comprising at least one filler selected from sugars and sugar alcohols, and microcrystalline cellulose.Type: ApplicationFiled: December 18, 2009Publication date: November 17, 2011Applicant: RATIOPHARM GMBHInventors: Sven Winter, Max-Werner Scheiwe
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Publication number: 20110189121Abstract: The invention relates to a method for producing tablets comprising a polyallylamine polymer, comprising the steps (i) preparation of a polyallylamine polymer or pharmaceutically compatible salts thereof, optionally in a mixture with one or more pharmaceutical excipients; (ii) compaction to give a slug; (iii) granulation of the slug; and (iv) compression of the resulting granules to give tablets; and also to tablets, sachets and slugs comprising a compacted polyallylamine polymer. In addition, the invention relates to tablets comprising a polyallylamine polymer, in particular Sevelamer, with a bimodal pore size distribution.Type: ApplicationFiled: March 20, 2009Publication date: August 4, 2011Applicant: ratiopharm GmbHInventors: Maria Genth, Max-Werner Scheiwe
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Patent number: 6492395Abstract: A pharmaceutically acceptable topical formulation for the treatment and/or prevention of skin ailments, more particularly of fibriotic nature such as fibriotic lesional tissues, contiguous warts, contact dermatitis, and keloids, and to assist the healing of burns after surgery, comprising as active ingredient a substituted pyridone of the formula: n-(R1)-R2-2-(1H)pyridone or a pharmaceutically acceptable salt or ester thereof, where R1 is selected from methyl, ethyl, propyl, carboxyl and a carboxymethyl or carboxyethyl ester group, R2 is selected from phenyl, methylphenyl, ethylphenyl, propylphenyl, and a carboxyphenyl or carboxyethylphenyl ester group, and n is 3, 4 or 5, together with an excipient, characterized in that the excipient comprises, one or more plasticisers, one or more antioxidants, one or more gel-forming agents and sufficient pH adjusting agent to bring the pH of the formulation to a value from 4 to 8. The preferred active ingredient is 5-methyl-1-phenyl-2-(1H)pyridone (Pirfenidone).Type: GrantFiled: May 23, 2001Date of Patent: December 10, 2002Assignee: Mepha AGInventors: Max Werner Scheiwe, Shitotomo Yamauchi
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Patent number: 6306896Abstract: The invention relates to a pharmaceutically active composition containing a substance which is active against malaria parasites and shows a high level of activity against multiresistant lines of Plasmodium falciparum. The inventive composition is characterized in that it contains the active agent artemisinine and/or a derivative of artemisinine in a carrier material which is inert with the active agent, in a pharmaceutically active quantity and in that the carrier material is essentially free of compounds with a hydrophilic-lipophilic balance between 7 and 9.9.Type: GrantFiled: June 12, 2000Date of Patent: October 23, 2001Assignee: Mepha AGInventor: Max Werner Scheiwe
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Patent number: 6149942Abstract: A pharmaceutical pellet formulation having a core containing omeprazole as an active ingredient, and also having an outer, enteric coating encasing the core. Titanium dioxide is added to the core, and optionally, to the enteric coating in order to retard decomposition of the omeprazole resulting from the action of penetrating moisture and solvents, thus greatly improving the storage stability of the omeprazole formulation.Type: GrantFiled: January 9, 1998Date of Patent: November 21, 2000Assignee: Melpha AGInventors: Max Werner Scheiwe, Thomas Villiger
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Patent number: 4473739Abstract: There is provided an apparatus for warming aqueous suspensions or solutions of living cell substances contained in frozen form in a substantially flat plastic bag comprising two heater plates selectively movable against each other, which serve to receive the plastic bag containing the frozen sample, the temperature of these heater plates being programmable and the heater plates being supported by a holding device which is movable over a fixed base plate, this holding device being capable of being caused to swivel rhythmically in an elliptic direction by means of a swivelling device attached to it.Type: GrantFiled: June 16, 1982Date of Patent: September 25, 1984Assignee: Helmholtz-Institut fur Biomedizinische TechnikInventors: Max-Werner Scheiwe, Gunter Rau