Abstract: A bio-hazardous waste compactor is described which provides a negative air pressure and venting system while allowing for the filtration of the air and control of sound. The compactor contains a sealed chamber which includes a sump area in the bottom of the chamber for fluid control. Waste is weighed so that the operator knows when to remove the waste. Ultraviolet light is provided to prevent the growth of vegetative pathogenic organisms. Finally, a disposable bag to be used in connection with such a bio-hazardous waste compactor is described which has an inner porous layer, an intermediate, biocide-containing, super-absorbent polymer layer and an outer non-porous layer.