Patents by Inventor MAXIME FEYEUX

MAXIME FEYEUX has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20250059504
    Abstract: The invention relates to a cellular microcompartment comprising successively, organized around a lumen, at least one layer of pluripotent cells, an extracellular matrix layer and an outer hydrogel layer. The invention also relates to processes for preparing such cellular microcompartments.
    Type: Application
    Filed: October 15, 2024
    Publication date: February 20, 2025
    Inventors: MAXIME FEYEUX, KEVIN ALESSANDRI, PIERRE NASSOY, LAURENT COGNET, GAËLLE RECHER, ERWAN BEZARD
  • Publication number: 20240018469
    Abstract: The invention relates to a cellular microcompartment comprising successively, organized around a lumen, at least one layer of pluripotent cells, an extracellular matrix layer and an outer hydrogel layer. The invention also relates to processes for preparing such cellular microcompartments.
    Type: Application
    Filed: September 29, 2023
    Publication date: January 18, 2024
    Inventors: MAXIME FEYEUX, KEVIN ALESSANDRI, PIERRE NASSOY, LAURENT COGNET, GAELLE RECHER, ERWAN BEZARD
  • Publication number: 20230257699
    Abstract: The invention relates to a neural tissue unit for use in implantation into the nervous system of a human or non-human mammal, wherein said neural tissue unit contains differentiated post-mitotic neuronal cells in an extracellular matrix, said unit being obtained from a cellular microcompartment comprising a hydrogel capsule surrounding the neural tissue unit, and said hydrogel capsule being at least partially removed before use of the neural tissue unit. The invention also relates to a process for preparing such a neural tissue unit.
    Type: Application
    Filed: March 22, 2023
    Publication date: August 17, 2023
    Inventors: MAXIME FEYEUX, KEVIN ALLESSANDRI, PIERRE NASSOY, LAURENT COGNET, ABDELHAMID BENAZZOUZ, ERWAN BEZARD
  • Publication number: 20230117999
    Abstract: The invention relates to a cellular microcompartment comprising successively, organized around a lumen, at least one layer of pluripotent cells, an extracellular matrix layer and an outer hydrogel layer. The invention also relates to processes for preparing such cellular microcompartments.
    Type: Application
    Filed: December 19, 2022
    Publication date: April 20, 2023
    Inventors: MAXIME FEYEUX, KEVIN ALESSANDRI, PIERRE NASSOY, LAURENT COGNET, GAELLE RECHER, ERWAN BEZARD
  • Publication number: 20220356445
    Abstract: The present invention relates to a method for in-vitro production of mammalian neurons expressing the 6 isoforms of the Tau protein (2N4R, 1N4R, 0N4R, 2N3R, 1N3R, 0N3R), comprising a step of neuronal differentiation, in which cellular microcompartments are cultivated for a period of 5 weeks to 100 weeks, each one comprising a hollow hydro gel capsule surrounding post-mitotic neuronal cells and an extracellular matrix, the neuronal differentiation step being carried out in a bioreactor, the cellular microcompartments being kept in suspension in an enclosure of the bioreactor containing a neuronal differentiation medium.
    Type: Application
    Filed: July 3, 2020
    Publication date: November 10, 2022
    Inventors: MAXIME FEYEUX, KEVIN ALESSANDRI, MAGALIE LECOURTOIS, LAETITIA MIGUEL, PIERRE NASSOY, ANNE ROVELET LECRUX
  • Publication number: 20210123013
    Abstract: The invention relates to a bioreactor cell culture system comprising a closed chamber containing a plurality of suspended cell microcompartments, wherein the microcompartments each comprise an outer hydrogel layer providing a cavity containing a set of self-organized cells and extracellular matrix or an extracellular matrix substitute. The invention further relates to the use of such bioreactors to produce cells and/or organoids, and/or molecules and/or complex molecular assemblies.
    Type: Application
    Filed: May 20, 2019
    Publication date: April 29, 2021
    Inventors: MAXIME FEYEUX, KEVIN ALESSANDRI, PIERRE NASSOY
  • Publication number: 20200360888
    Abstract: The invention relates to a process for producing a plurality of capsules, each comprising an external shell of crosslinked hydrogel surrounding a central core, according to which a hydrogel solution and a composition of interest, intended to form the central core, are concentrically co-extruded so as to form mixed drops, each comprising a layer of hydrogel solution surrounding a drop of liquid composition of interest, characterized in that the co-extrusion step is carried out above a crosslinking aerosol so that the mixed drops pass through said crosslinking aerosol, such that the layer of hydrogel solution at least partially crosslinks around the drop of liquid composition of interest on contact with said aerosol.
    Type: Application
    Filed: November 20, 2018
    Publication date: November 19, 2020
    Inventors: MAXIME FEYEUX, KEVIN ALESSANDRI, PIERRE NASSOY
  • Publication number: 20200063099
    Abstract: The invention relates to a neural tissue unit for use in implantation into the nervous system of a human or non-human mammal, wherein said neural tissue unit contains differentiated post-mitotic neuronal cells in an extracellular matrix, said unit being obtained from a cellular microcompartment comprising a hydrogel capsule surrounding the neural tissue unit, and said hydrogel capsule being at least partially removed before use of the neural tissue unit. The invention also relates to a process for preparing such a neural tissue unit.
    Type: Application
    Filed: November 23, 2017
    Publication date: February 27, 2020
    Inventors: MAXIME FEYEUX, KEVIN ALESSANDRI, PIERRE NASSOY, LAURENT COGNET, ABDELHAMID BENAZZOUZ, ERWAN BEZARD
  • Publication number: 20200002681
    Abstract: The invention relates to a hollow cell microfibre comprising successively, organized around a lumen, at least one endothelial cell layer, at least one smooth muscle cell layer, an extracellular matrix layer, and optionally an outer hydrogel layer. The invention also relates to a process for fabricating such a hollow cell microfibre.
    Type: Application
    Filed: March 8, 2018
    Publication date: January 2, 2020
    Inventors: LAETITIA ANDRIQUE, GAËLLE RECHER, KEVIN ALESSANDRI, MAXIME FEYEUX, PIERRE NASSOY, ANDRÉAS BIKFALVI
  • Publication number: 20190330589
    Abstract: The invention relates to a cellular microcompartment comprising successively, organized around a lumen, at least one layer of pluripotent cells, an extracellular matrix layer and an outer hydrogel layer. The invention also relates to processes for preparing such cellular microcompartments.
    Type: Application
    Filed: November 23, 2017
    Publication date: October 31, 2019
    Inventors: MAXIME FEYEUX, KEVIN ALESSANDRI, PIERRE NASSOY, LAURENT COGNET, GAËLLE RECHER, ERWAN BEZARD