Patents by Inventor Maximilian A. Horlbeck

Maximilian A. Horlbeck has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • CONTROL OF MAMMALIAN GENE DOSAGE USING CRISPR
    Publication number: 20220259593
    Abstract: The present disclosure provides methods and compositions for precisely controlling the expression levels of mammalian genes using CRISPRi or CRISPRa and one or more modified sgRNAs. The methods and compositions are useful for, inter alia, titrating the expression of a gene of interest, identifying drug targets and mechanisms of drug resistance, and enabling the analysis of and control over metabolic and signaling pathway fluxes.
    Type: Application
    Filed: January 25, 2022
    Publication date: August 18, 2022
    Applicant: The Regents of the University of California
    Inventors: Jonathan Weissman, Marco Jost, Maximilian A. Horlbeck, Daniel Santos, Reuben Saunders
  • COMPOSITIONS AND METHODS FOR CRISPR-BASED SCREENING
    Publication number: 20190300868
    Abstract: Provided herein are compositions and methods for CRISPR-based screening.
    Type: Application
    Filed: December 15, 2017
    Publication date: October 3, 2019
    Inventors: Luke Gilbert, Maximilian A. Horlbeck, Marco Jost, Jonathan Weissman