Patents by Inventor Maximilian C.R. Buff

Maximilian C.R. Buff has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • INHIBITION OF VIRAL GENE EXPRESSION
    Publication number: 20140350080
    Abstract: This invention relates to modified short interfering RNA (siRNA) nucleic acid molecules, particularly siRNA's which have been modified by the addition of a 2-0-guanidinopropyl (GP) modified nucleoside. In particular the invention relates to modified siRNAs which are capable of silencing target sequences, methods of treating and preventing infection by using the siRNAs, medicaments containing the siRNAs and use of the siRNAs.
    Type: Application
    Filed: October 26, 2012
    Publication date: November 27, 2014
    Applicant: UNIVERSITY OF THE WITWATERSRAND, JOHANNESBURG
    Inventors: Patrick Arbuthnot, Justin Hean, Abdullah Ely, Musa Marimani, Jolanta Brzezinska, Jennifer D'Onofrio, Maximilian C.R. Buff, Joachim W. Engels, Stefan Bernhardt