Abstract: A solution is proposed for imaging a body-part (103) of a patient (106) with an endoscopic system (100). A corresponding method (500) comprises acquiring (509-515) two sequences of images with different probes (127n,127b), of corresponding endoscopic units (115m,115b), that are movable therebetween. Corresponding images of each pair in the two sequences are registered (518-584), for example, according to corresponding motions of their probes (127n,127b) that are estimated independently each according to the corresponding images. A method (800) is also proposed for training a neural network (439) that may be used to register the images. Corresponding computer programs (400;700) and computer program products for operating the endoscopic system (100) and for training the neural network (439) are proposed.

Abstract: A solution is proposed for imaging an object containing a luminescence substance. A corresponding method (500) is based on a refining loop. At each iteration of the refining loop, different spatial patterns are determined (516-518, 524;536-540, 546), partial illuminations corresponding to the spatial patterns are applied to the object (520,526;542,548), component images are acquired in response to the partial illuminations (522,528;544,550) and the component images are combined (530;552) into a combined image. A corresponding system (100) is also proposed. Moreover, a computer program (400) and a corresponding computer program product are proposed. A diagnostic method, a surgical method and a therapeutic method based on the same solution are further proposed.

Abstract: A solution for imaging one or more body-parts (109) of a patient (106) in a medical application is proposed. A corresponding method (500) comprises determining (533-536) a mapping function that maps a global range of the values of a plurality of luminescence images of the body-parts (109) to a (common) dynamic range of a displayer (169). The luminescence images are mapped (539-545) by converting their values according to the mapping function. The resulting mapped luminescence images are then displayed (584) together on the displayer (169). In addition or in alternative, the method (500) comprises providing (557) at least one (common) segmentation threshold for starting images equal to the luminescence images or to the mapped luminescence images. The starting images are segmented (560-569) each according to a comparison of the values of the starting image with the segmentation threshold. A computer program (400) and a corresponding computer program product for implementing the method (500) are also proposed.

Abstract: A solution is proposed for imaging a field of view (103) comprising a target (115) containing a luminescence substance. A corresponding method (500) comprises setting (512-552) an analysis region (225;260) to a portion of a luminescence image 5(205;205F) surrounding a suspected representation of the target (115) and segmenting (554-556) the analysis region (225;260) into a detection segment (230d;265d) and a non-detection segment (230n;265n) of the luminescence substance; the luminescence image (205;205F) is then displayed (558-586) with the detection segment (230d;265d) that is highlighted according to a verification indicator based on a quality of the 0segmentation. A computer program (400) and a corresponding computer program product for implementing the method (500) are also proposed. Moreover, a corresponding system (100) is proposed. A surgical method, a diagnostic method and a therapeutic method based on the same solution are further proposed.

Abstract: A solution is proposed for testing a luminescence imaging apparatus (105). A corresponding testing device (110) comprises one or more seats (320) and one or more containers (325), each filled with a liquid comprising at least one luminescence substance and accommodated in a corresponding seat (320); the seats (320) have corresponding windows (330) for imaging the luminescence substance of the containers (325) accommodated therein. The seats (320) are slanted with respect to a resting surface (310) of the testing device (110). A holder (305) for use in the testing device (100) is further provided. A luminescence imaging apparatus (105) for use with the testing device (110) is also proposed. Moreover, a system (100) comprising a luminescence imaging apparatus (105) and this testing device (110) is proposed.

Abstract: A solution is proposed for testing a luminescence imaging apparatus (105). A corresponding method (700) comprises acquiring (706) a photograph image and finding (708) a position of the testing device (110) in the photograph image. The 5method further comprises acquiring (706) a luminescence image and determining (734-736) a representation of sites of the testing device (110), each comprising at least one luminescence substance, in the luminescence image according to the position of the testing device (110) in the photograph image. The luminescence imaging apparatus (105) is then tested (754-772) according to the representation of the sites (330) in the 0luminescence image. A corresponding computer program (600) and a computer program product for implementing the method (700) are also proposed. Moreover, a testing device (110) for use in the method (700) is proposed.

Abstract: A solution is proposed for imaging an object containing a luminescence substance. A corresponding method (500) is based on a refining loop. At each iteration of the refining loop, different spatial patterns are determined (516-518, 524;536-540, 546), partial illuminations corresponding to the spatial patterns are applied to the object (520,526;542,548), component images are acquired in response to the partial illuminations (522,528;544,550) and the component images are combined (530;552) into a combined image. A corresponding system (100) is also proposed. Moreover, a computer program (400) and a corresponding computer program product are proposed. A diagnostic method, a surgical method and a therapeutic method based on the same solution are further proposed.

Abstract: The invention relates to a system for endoscopic imaging comprising a light source configured to generate light and an, in particular rigid, insertion portion configured to be inserted into an object and comprising a distal end, a proximal end and at least one light guiding path. The system further comprises a first imaging device mounted at the proximal end of the insertion portion and optically coupled to the light guiding path, the first imaging device comprising a plurality of first detecting elements exhibiting a first sensitivity to light. A flexible guiding portion comprising a distal end and a proximal end is provided to guide a second part of the light emanating from the medium from the distal end of the guiding portion to the proximal end of the guiding portion.

Abstract: The invention relates to a system for endoscopic imaging comprising a light source configured to generate light and an, in particular rigid, insertion portion configured to be inserted into an object and comprising a distal end, a proximal end and at least one light guiding path. The system further comprises a first imaging device mounted at the proximal end of the insertion portion and optically coupled to the light guiding path, the first imaging device comprising a plurality of first detecting elements exhibiting a first sensitivity to light. A flexible guiding portion comprising a distal end and a proximal end is provided to guide a second part of the light emanating from the medium from the distal end of the guiding portion to the proximal end of the guiding portion.